Protein Alignment Man2a1 and LManIII

DIOPT Version :9

• Sequence 1: NP_032575.2
• Gene: Man2a1 / 17158
• MGIID: 104669
• Length: 1150
• Species: Mus musculus
• Sequence 2: NP_001285762.1
• Gene: LManIII / 34203
• FlyBaseID: FBgn0032066
• Length: 1003
• Species: Drosophila melanogaster
• Alignment Length: 1102
• Identity: 273/1102 - (24%)
• Similarity: 454/1102 - (41%)
• Gaps: 236/1102 - (21%)

Mouse   155 YEA-DEWDHEPLQVFVVPHSHNDPGWLKTFNDYFRDK--------TQYIFNNMVLKLKEDSSRKF 210
            ||: .|.....:.:.:|||||:|.|||||.:.|:...        .||||:.:|.:|.:||.|:|
  Fly    26 YESCPETKSNMINIHLVPHSHDDLGWLKTVDQYYYGNKHNIQHAGVQYIFDTVVAELSKDSRRRF 90

Mouse   211 MWSEISYLAKWWDIIDIPKKEAVKSLLQNGQLEIVTGGWVMPDEATPHYFALIDQLIEGHQWLEK 275
            :..|..:.||||:.....||:.||:|:..|:||...|.|.|.|||..:|.::|||...|.::|..
  Fly    91 IQVETGFFAKWWEDQSETKKKLVKTLVNEGRLEFTGGAWSMNDEAAVNYQSVIDQFAVGLKFLND 155

Mouse   276 NLGV--KPRSGWAIDPFGHSPTMAYLLKRAGFSHMLIQRVHYAIKKHFSLHKTLEFFWRQNWDLG 338
            |.||  :||.||.||.||||...|.:..:..|......|:....|.....:..||..|
  Fly   156 NFGVCGRPRVGWQIDAFGHSREQASMFAQMAFDGQFFARMDQNDKNKRVDNLGLEMVW------- 213

Mouse   339 SATDILCHMMPFYSYDIPHTCGPDPKIC----CQFDFKRLPGGRYGCPWGVPPEAISPGNVQSRA 399
            .|::.|..|..|......|...| |..|    || |...:.|..|            ..||:||.
  Fly   214 DASETLEEMDFFTGMLYNHYSAP-PGFCFDSLCQ-DDPIIDGKSY------------DNNVKSRV 264

Mouse   400 QMLLDQYRKKSKLFRTKVLLAPLGDDFRFSEYTEWDLQCRNYEQLFSYMNSQ--PHLKVKIQFGT 462
            ...|:.....:..:|:..::.|:||||   :|....:..:|.::|..|:|.:  ...|..|.:.|
  Fly   265 DDFLNYASNLAGYYRSNHIMVPMGDDF---QYENAYMNYKNMDKLIKYVNERQASGSKYNIFYST 326

Mouse   463 LSDYFDALEKAVAAEKKSSQSVFPALSGDFFTYADRDDHYWSGYFTSRPFYKRMDRIMESRIRAA 527
            ...|.::|.|::.:        ||..:.||..::.....:|:|:|||||..||.:|.....::.|
  Fly   327 AGCYLNSLHKSLQS--------FPNKTQDFLPHSHEAKSFWTGFFTSRPTQKRFERDGNHILQVA 383

Mouse   528 EILYQLA-LKQAQKYKINKFLSSPHYTTLTEARRNLGLFQHHDAITGTAKDWVVVDYGTRLFQSL 591
            :.|..|| |...:::|...:|           |:.:.:.|||||||||.|..|..||...|:.::
  Fly   384 KQLSVLADLSGEEQHKDLDYL-----------RQIMAVMQHHDAITGTEKQEVSNDYDRLLYDAI 437

Mouse   592 NSLEKIIGDSAFLLILKDKKLYQSDPSKAFLEMD------TKQSSQDSLPQKIIIQLSAQEPRYL 650
            ........|:..:|..:....:||     .|:::      ||:::.|.:               :
  Fly   438 LGGANTARDALRVLTNQPNGEFQS-----CLKLNISECAFTKENADDFM---------------V 482

Mouse   651 VVYNPFEQERHSVVSIRVNSATVKVLSDSGKPVEVQVSAV-WN----DMRTISQAAYEVSFLAHI 710
            .:|||........|.:.|...:.:|..:.|..|..::..| |.    :.|. :...:|:.|.|.:
  Fly   483 TLYNPLAHTSTQYVRVPVKEDSYQVTDEKGGLVASELVPVPWEVLSLEFRN-NDTQHELVFKASV 546

Mouse   711 PPLGL----------------------------------KVFKILESQSSSSHLADYVLYNNDGL 741
            ..:..                                  |.||.:.|..:.....|    :.:.:
  Fly   547 NKIATYFIKKIDKTTEVDITVNTQTEQSVNEEESNVKVPKRFKKVHSLKTDLETLD----DQETI 607

Mouse   742 AENGIFHVKNMVD--AGDAITIENPFLAIWFDRSGLMEKVRRKEDSRQHELKVQFLWYGTTNKRD 804
            .:|.:  :|.::|  .|...|:|         .:|:.|           ::...|..|.|.
  Fly   608 VQNSL--IKLVIDNNTGRLKTVE---------MNGVSE-----------DIDQTFGMYKTA---- 646

Mouse   805 KSGAYLFLPDGQGQPYVSLRPPF-VRVTRGRIYSDVTCFL-EHVTHKVRLYNIQGIEGQSME-VS 866
            :|..|:|..|...:   .:...| ..|..|....:|...: |.::..:|:|  :|:.....| :.
  Fly   647 RSCHYIFRQDADLE---LVEDAFDFTVYDGESVKEVHQHVNEWISQVIRIY--EGVNRVEFEWLV 706

Mouse   867 NIVNIRNVHNREIVMRISSKINNQNRYYTDLNGYQIQPRR---------TMSKLPLQANVYPMCT 922
            ..|.|.:...:|||....|.|::...:|||.||.::..|.         .:|:.|:..|.||:.:
  Fly   707 GPVPIDDELGKEIVTIFKSGISSGGVFYTDSNGREMMRREKDKREDFSPDLSEQPVSGNYYPVTS 771

Mouse   923 MAYIQDAEHRLTLLSAQSLGASSMASGQIEVFMDRRLMQDDNRGLGQGVHDNKITANLF---RIL 984
            ...:||:..|:.||:.:|.|.:|:..|::|:.:.||.:..|..|..:.:::.:....|.   ::.
  Fly   772 RMALQDSSKRMVLLNDRSQGGASLEDGRLEMMLHRRHIFADGSGAAEAINEQQFGKGLIARGKLF 836

Mouse   985 L------EKRSAVNMEEEKKSPVSYPSLLSHMTSSFLNHPFLPMVLSGQLPSPAFELLSEFPLLQ 1043
            |      :..:|.....||:..:.:....|.               |..:.|...:.||:|
  Fly   837 LYLNAIEDGATASERVAEKEIHLPFWKFFSK---------------SNNIQSDVTKTLSDF---- 882

Mouse  1044 SSLPCDIHLVNLRTIQSKMGKGYS-DEAALILHR-----KGFDCQFSSR-------GIGLPCSTT 1095
            :.||..:||:.|        :.|| ||..|.|..     :|....||.|       |:.:..:|.
  Fly   883 NDLPQSVHLLTL--------EPYSKDEILLRLENFLDQTEGNVVSFSIRQIFDDLGGLEIRETTL 939

Mouse  1096 QGK-----MSVLKLFNKFAVES-LVPSSLSLMHSPPDA---QNMSE--VSLSPMEISTFRIR 1146
            .|.     |..||..:..:..| .||...:.:|.|..|   |:.||  |:|.||:|.||.|:
  Fly   940 DGNLPLSDMKRLKFHHDGSGPSHSVPEYFTSLHKPLAADKTQDASEFSVTLKPMQIRTFIIK 1001

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Man2a1	NP_032575.2	PLN02701	127..1148	CDD:178304	273/1102 (25%)
		GH38N_Man2A1	164..507	CDD:212131	108/358 (30%)
		Alpha-mann_mid	502..587	CDD:214875	31/85 (36%)
		Glyco_hydro_38C	757..1143	CDD:285047	98/430 (23%)
LManIII	NP_001285762.1	GH38N_AMII_LAM_like	37..311	CDD:212121	95/297 (32%)
		Alpha-mann_mid	358..433	CDD:286360	31/85 (36%)
		Glyco_hydro_38C	603..998	CDD:285047	102/452 (23%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG1959
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810