DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Mageb1 and MAGE

DIOPT Version :9

Sequence 1:	NP_034889.1	Gene:	Mageb1 / 17145	MGIID:	105118	Length:	380	Species:	Mus musculus
Sequence 2:	NP_649702.2	Gene:	MAGE / 40860	FlyBaseID:	FBgn0037481	Length:	232	Species:	Drosophila melanogaster

Alignment Length:	207	Identity:	52/207 - (25%)
Similarity:	101/207 - (48%)	Gaps:	11/207 - (5%)

- Green bases have known domain annotations that are detailed below.

Mouse   150 DPIMRKASVLIEFLLDKFKMKEAVTRSEMLAVVNKK--YKEQFPEILRRTSARLELVFGLELKEI 212
            |.:..|...::.::||....|..:...:::||...|  .|::.|.:   |:...| .||:.|..:
  Fly    24 DVVDAKVRAILNYILDHTAQKIPIKDKDLIAVAGDKSELKKRLPLV---TNLLAE-TFGIILTPL 84

Mouse   213 DPSTHSYLLVGKLGLSTEGSLSSNWGLPRTGLLMSVLGVIFMKGNRATEQEVWQFLHGVGVYAGK 277
            |.:|.:::...:..:::...|:.. ..|:..||..:|..||::|||..:.:::..|..:.:|..:
  Fly    85 DATTKTFICTAEEPVASIHELTPA-QRPQFTLLYIILMYIFLRGNRIEDSKLYVMLEMLNIYPDE 148

Mouse   278 KHLIFGE--PEEFIRDVVRENYL--EYRQVPGSDPPSYEFLWGPRAHAETTKMKVLEVLAKVNGT 338
            :|..||.  .::.....|::.||  |..|:...|.....|||||||.||.|..::::..:|:...
  Fly   149 EHGYFGPNLRKQIEETFVKQQYLKRERSQLSAYDDSKTFFLWGPRAKAEFTFEQMVQFASKLLNQ 213

Mouse   339 VPSAFPNLYQLA 350
            .|..|.:...:|
  Fly   214 HPKVFGHHLSMA 225

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Mageb1	NP_034889.1	MAGE_N	55..125	CDD:289225
Mageb1	NP_034889.1	MAGE	173..326	CDD:279759	43/158 (27%)
MAGE	NP_649702.2	MAGE	36..201	CDD:279759	46/169 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167842094
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4562
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1195799at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	4	3.800