DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lyl1 and Fer1

DIOPT Version :9

Sequence 1:	NP_032561.2	Gene:	Lyl1 / 17095	MGIID:	96891	Length:	278	Species:	Mus musculus
Sequence 2:	NP_001262334.1	Gene:	Fer1 / 2768661	FlyBaseID:	FBgn0037475	Length:	256	Species:	Drosophila melanogaster

Alignment Length:	153	Identity:	44/153 - (28%)
Similarity:	65/153 - (42%)	Gaps:	26/153 - (16%)

- Green bases have known domain annotations that are detailed below.

Mouse   143 HQP-------QKVARRVFTNSRERWRQQHVNGAFAELRKLLPTHPPDRKLSKNEVLRLAMKYIGF 200
            |:|       |...:|...|.|||.|.|.:|.||..||..:||.|.:::|||.:.|:||:.||.|
  Fly    73 HKPRRLKCASQMAQQRQAANLRERRRMQSINEAFEGLRTHIPTLPYEKRLSKVDTLKLAISYITF 137

Mouse   201 LVRLLRDQTAVLTSGPSAPG------SRKPPARRGVEGSARFGAGHRVEAARSQPVLPGD----- 254
            |..:::..     ...:.||      .:|.|.::.:......|..|.:...|.....||.
  Fly   138 LSEMVKKD-----KNGNEPGLSLQRNYQKEPPKKIILKDRTGGVAHSLSWYRKGDRYPGSKLYAR 197

Mouse   255 --CDGDPNG-SVRPIKLEQTSLS 274
              ...||.| ..:|:.|...|.|
  Fly   198 TWTPEDPRGPHSQPLPLYNNSNS 220

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lyl1	NP_032561.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..46
		bHLH_TS_LYL1	145..209	CDD:381548	27/70 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	212..278		16/77 (21%)
Fer1	NP_001262334.1	HLH	92..144	CDD:197674	24/51 (47%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG4029
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810