DRSC/TRiP Functional Genomics Resources

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Protein Alignment Il1rl1 and Dscam2

DIOPT Version :9

Sequence 1:NP_001020773.1 Gene:Il1rl1 / 17082 MGIID:98427 Length:567 Species:Mus musculus
Sequence 2:NP_001261500.1 Gene:Dscam2 / 38788 FlyBaseID:FBgn0265296 Length:2101 Species:Drosophila melanogaster


Alignment Length:424 Identity:88/424 - (20%)
Similarity:143/424 - (33%) Gaps:133/424 - (31%)


- Green bases have known domain annotations that are detailed below.


Mouse     6 RMGLWALAILTLPMYLTVTEGSKSSWGLENEALIVRCPQRGRSTYPV-EWYYSDTNESIPTQKRN 69
            |:.::.|..:.|...:|...|         |.|.::||..|   ||: |.::......:|...|.
  Fly   514 RLNIYGLPYIRLIPKVTAVSG---------ETLNLKCPVAG---YPIEEIHWERGGRELPDDIRQ 566

Mouse    70 RIFVSRD-RLKFLPA-RVEDSGIYACVIRSP---NLNKTGYLNVTIHKK--PPSCNIPDYLMYST 127
            |  |..| .|...|. :..|||:|.|..|:.   :..::|.:.|.:..|  |...||....|   
  Fly   567 R--VQPDGSLTISPVQKNSDSGVYTCWARNKQGHSARRSGEVTVIVPPKLSPFQTNILQLNM--- 626

Mouse   128 VRGSDKNFKITCPTI--DLYNWTAPVQWFKNCKALQEPRFRA------HRSYLFIDNVTHDDEGD 184
               .|: ..:||..:  ||   ...:.|.|:.:.:...:..:      :.|.|.|:|:..|..|:
  Fly   627 ---GDR-ASLTCSVVKGDL---PLTINWRKDGRPIDPTQHMSVKQVDQYNSILVIENLGSDHTGN 684

Mouse   185 YTC----QFTHAENGTNYIVTATRSFTVEEKGFSMFPVITNPPYN-----HTMEVEIGKPASIAC 240
            |:|    .....||....:|.....:.||       ||..|...|     |.....:..|:.:..
  Fly   685 YSCVVRNSAAEVENSQALLVNVPPRWIVE-------PVDANVERNRHIMLHCQAQGVPTPSIVWK 742

Mouse   241 SA------------------CFGKGSHFLADV--------LWQINK---TVVGNFGEARIQE--- 273
            .|                  ..|.||..|..|        |.|.|.   |.:|...:.::..   
  Fly   743 KATGSKSGEYEEVRERPFTKLLGNGSLLLQHVKEDREGFYLCQANNGIGTGIGKVIQLKVNSSPY 807

Mouse   274 ---------------------------------EEGRN--ESSSN---------DMDCLTSVLRI 294
                                             ..|:|  ..|:|         ..|.:::.|:|
  Fly   808 FSSTSRSVMVKKGDTALLQCAVSGDKPINIVWMRSGKNTLNPSTNYKISVKQEATPDGVSAELQI 872

Mouse   295 TGVTEKDLSLEYDCLALNLHGMIRHTIRLRRKQP 328
            ..|...| |..|.|.|.||:|..:..::|:.::|
  Fly   873 RTVDATD-SGPYFCRASNLYGNDQQLVQLQVQEP 905

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Il1rl1NP_001020773.1 Ig 33..97 CDD:416386 20/66 (30%)
Ig strand B 37..42 CDD:409353 1/4 (25%)
Ig strand C 51..55 CDD:409353 2/4 (50%)
Ig strand C' 60..62 CDD:409353 0/1 (0%)
Ig strand D 70..74 CDD:409353 1/3 (33%)
Ig strand E 76..80 CDD:409353 2/4 (50%)
Ig strand F 89..97 CDD:409353 3/7 (43%)
Ig2_IL1R-like 124..210 CDD:409415 20/97 (21%)
Ig strand B 135..139 CDD:409415 0/3 (0%)
Ig strand C 150..154 CDD:409415 0/3 (0%)
Ig strand E 170..174 CDD:409415 2/3 (67%)
Ig strand F 184..189 CDD:409415 2/8 (25%)
Ig strand G 201..204 CDD:409415 0/2 (0%)
Flexible linker. /evidence=ECO:0000250 204..216 2/11 (18%)
Ig <291..324 CDD:416386 11/32 (34%)
Ig strand E 291..294 CDD:409353 1/2 (50%)
Ig strand F 305..310 CDD:409353 2/4 (50%)
Ig strand G 318..321 CDD:409353 0/2 (0%)
TIR 385..540 CDD:396246
Dscam2NP_001261500.1 Ig 51..127 CDD:299845
Ig 138..>203 CDD:299845
I-set 238..327 CDD:254352
Ig 247..327 CDD:299845
I-set 332..418 CDD:254352
IGc2 344..407 CDD:197706
IG_like 432..517 CDD:214653 1/2 (50%)
IGc2 436..507 CDD:197706
I-set 521..610 CDD:254352 26/102 (25%)
IGc2 533..597 CDD:197706 22/77 (29%)
Ig 630..699 CDD:143165 15/71 (21%)
IG_like 714..802 CDD:214653 17/87 (20%)
Ig 725..802 CDD:299845 13/76 (17%)
Ig 823..894 CDD:143165 16/71 (23%)
FN3 906..1006 CDD:238020 88/424 (21%)
FN3 1013..1111 CDD:238020
FN3 1119..1209 CDD:238020
FN3 1219..1313 CDD:238020
Ig 1336..1402 CDD:143165
FN3 1409..1498 CDD:238020
FN3 1515..1588 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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