DRSC/TRiP Functional Genomics Resources

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Protein Alignment Cd180 and Tehao

DIOPT Version :9

Sequence 1:NP_032559.2 Gene:Cd180 / 17079 MGIID:1194924 Length:661 Species:Mus musculus
Sequence 2:NP_001285901.1 Gene:Tehao / 34761 FlyBaseID:FBgn0026760 Length:795 Species:Drosophila melanogaster


Alignment Length:621 Identity:128/621 - (20%)
Similarity:235/621 - (37%) Gaps:177/621 - (28%)


- Green bases have known domain annotations that are detailed below.


Mouse   171 PTEKLKVLDF-QNNAIHYLSKEDMSSLQQATNLSLNLNGNDIAGIELGAFDSAVFQSLNFGGTQN 234
            |.|...:|:. :..|..|:|....:.||.....::    :.:..||   ||:.:|....|     
  Fly    52 PDEYAMLLEVSEPGASLYMSYYASTELQWLPRFNI----SSLVKIE---FDAYIFWPEKF----- 104

Mouse   235 LLVIFKGLKNSTIQSLWL--GTFEDMDDEDISPAVFEGLCEMS-VESI---------NLQKHYFF 287
            |..:.|.|...|::::..  .|.|.:...|:..: ..|..|.| .|:|         .|:|..||
  Fly   105 LSDLLKTLGVQTVKTIIFRDRTLETVVTRDVLNS-GNGYMETSQPENITTWHFGSVPGLKKFKFF 168

Mouse   288 N----ISSNTFHCFSGLQELDLTATHLSELPSGLVGL--STLKKLVLSA--------------NK 332
            :    :..:.||.|..|::|.| :.:::.||..::..  .|||.|.:.:              .:
  Fly   169 SHVPELQESIFHGFDTLRDLHL-SVNVTTLPGNMLSTVNGTLKTLTIESPGIVSFGNPLLRELQQ 232

Mouse   333 FENLC------------QISASNFPSLTHLS---------------IKGNTKRLELGTGCLENLE 370
            ..||.            |:....|.|:|:|.               .|| |.:|:|..  :...:
  Fly   233 LRNLSLALIHPFHERDKQLQPHFFGSMTNLEEVRLASATSSVNRSMFKG-TNKLQLIK--MNGND 294

Mouse   371 NLREL--DLSHDDIETSDCCNLQLRNLSHLQSLNLSYNEPLSLKTEAFKECPQLELLDLAFTRLK 433
            :|.||  ::..|.:              :|::|:||.|..::|..:.||....|.||||:..|| 
  Fly   295 DLMELPGEIFLDQV--------------NLKTLDLSCNAIVTLHEDVFKGLGNLTLLDLSKNRL- 344

Mouse   434 VKDAQSPFQNLHLLKVLNLSHSLLDISSEQLFDGLPALQHLNLQGNHF----------------- 481
            ...:.:.|..|..|.||.|:.:.|...|..:|..:.:|.::.:....|                 
  Fly   345 TNLSSTIFAPLTSLNVLRLNKNSLTAMSPSVFQDVVSLNYIEMVNTQFYGATLLMNYEAVVCTND 409

Mouse   482 -------------PK------------------------GNIQKTNSLQTLGRLEILVLSFCDLS 509
                         |:                        .::.:|..|.|:  |::...|...|.
  Fly   410 EACQYKSAEWQCDPRCICWVQRSVGSLIVDCRGTSLEELPDLPRTTLLSTV--LKVGNNSLTSLP 472

Mouse   510 SIDQHAFTSLKMMNHVDLSHNRLTSSSI-----EALSHLKGIYLNLASNRISIILPSLLPILSQQ 569
            ::.:|  :....::.:.||.|.|||...     :.|:|     |::..|:|..:....|..|.:.
  Fly   473 TVSEH--SGYANVSGLFLSDNNLTSLGSGDQLPDNLTH-----LDVRGNQIQSLSDEFLLFLQEP 530

Mouse   570 R---TINLRQNPLDCTCSNIYFLEWYKENMQKLEDTEDTLC----ENPPLLRGVRLSD---VTLS 624
            .   |::|..||:.|.|.::..|.:.:.|.|::.|..|.:|    ::...:....|..   :.:|
  Fly   531 NNTMTLSLSGNPITCGCESLSLLFFVRTNPQRVRDIADIVCTKQKKSFQQMEAFELCPSYVLLIS 595

Mouse   625 CSMAAVGIFFLIVFLLVFAILLIFAVKYFLRWKYQH 660
            |.:.  |:..:|..|.||.::....:|.   |.|.:
  Fly   596 CVVG--GLVIVICLLTVFYLMFQQELKI---WLYNN 626

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Cd180NP_032559.2 leucine-rich repeat 38..57 CDD:275380
LRR 1 54..75
leucine-rich repeat 58..78 CDD:275380
LRR 2 78..99
leucine-rich repeat 79..102 CDD:275380
LRR 3 102..123
leucine-rich repeat 103..126 CDD:275380
LRR 4 126..147
leucine-rich repeat 127..150 CDD:275380
LRR 5 150..171 128/621 (21%)
leucine-rich repeat 151..174 CDD:275380 1/2 (50%)
LRR 6 174..195 4/21 (19%)
leucine-rich repeat 175..201 CDD:275380 6/26 (23%)
LRR 7 201..221 3/19 (16%)
leucine-rich repeat 224..275 CDD:275380 11/52 (21%)
LRR 8 275..296 8/34 (24%)
leucine-rich repeat 276..299 CDD:275380 9/35 (26%)
LRR 9 299..321 5/23 (22%)
leucine-rich repeat 300..322 CDD:275380 5/23 (22%)
LRR_8 321..382 CDD:290566 20/103 (19%)
LRR 10 322..343 7/46 (15%)
leucine-rich repeat 323..346 CDD:275380 7/48 (15%)
LRR_RI 345..>541 CDD:238064 52/271 (19%)
LRR 11 346..366 8/34 (24%)
leucine-rich repeat 347..371 CDD:275380 7/38 (18%)
LRR_8 371..432 CDD:290566 17/62 (27%)
LRR 12 371..391 4/21 (19%)
leucine-rich repeat 372..397 CDD:275380 4/26 (15%)
LRR 13 397..418 7/20 (35%)
leucine-rich repeat 398..421 CDD:275380 8/22 (36%)
LRR_8 420..481 CDD:290566 17/60 (28%)
LRR 14 421..442 7/20 (35%)
leucine-rich repeat 422..446 CDD:275380 9/23 (39%)
LRR 15 446..466 6/19 (32%)
leucine-rich repeat 447..470 CDD:275380 7/22 (32%)
LRR 16 470..493 4/76 (5%)
leucine-rich repeat 471..497 CDD:275380 6/79 (8%)
LRR_8 497..555 CDD:290566 14/62 (23%)
LRR 17 497..518 4/20 (20%)
leucine-rich repeat 498..521 CDD:275380 4/22 (18%)
LRR 18 521..544 8/27 (30%)
leucine-rich repeat 522..545 CDD:275380 8/27 (30%)
LRR 19 546..566 4/19 (21%)
LRRCT 577..626 CDD:214507 12/55 (22%)
TehaoNP_001285901.1 leucine-rich repeat 185..207 CDD:275380 5/22 (23%)
leucine-rich repeat 209..232 CDD:275380 3/22 (14%)
leucine-rich repeat 233..261 CDD:275380 5/27 (19%)
LRR_RI <261..370 CDD:238064 32/126 (25%)
leucine-rich repeat 262..284 CDD:275380 4/22 (18%)
leucine-rich repeat 285..309 CDD:275380 6/39 (15%)
LRR_8 309..368 CDD:290566 21/59 (36%)
leucine-rich repeat 310..333 CDD:275380 8/22 (36%)
leucine-rich repeat 334..357 CDD:275380 9/23 (39%)
leucine-rich repeat 358..381 CDD:275380 7/22 (32%)
leucine-rich repeat 445..482 CDD:275380 7/40 (18%)
LRR_8 459..516 CDD:290566 15/65 (23%)
leucine-rich repeat 483..505 CDD:275380 6/21 (29%)
LRR_4 486..521 CDD:289563 11/39 (28%)
TIR 643..779 CDD:214587
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E2759_KOG4641
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 1 1.010 - - D147327at33208
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.820

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