DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Kirrel and DIP-delta

DIOPT Version :9

Sequence 1:XP_011238330.1 Gene:Kirrel / 170643 MGIID:1891396 Length:805 Species:Mus musculus
Sequence 2:NP_001097508.2 Gene:DIP-delta / 5740816 FlyBaseID:FBgn0085420 Length:469 Species:Drosophila melanogaster


Alignment Length:538 Identity:116/538 - (21%)
Similarity:196/538 - (36%) Gaps:119/538 - (22%)


- Green bases have known domain annotations that are detailed below.


Mouse     9 RLMTCQSSLLPEKPRFLSQKMWAPHLVVAYLIFVT-LALALPGTQTRFSQEPADQTVVAGQRAVL 72
            :|:....::.|.  ||.:::       :.:||::| |...:...:.||:|...:.||..|:.|.|
  Fly     8 KLLLIALNIFPS--RFTNRR-------IMFLIYMTNLVTHVMMDEPRFAQPIPNVTVAVGRDANL 63

Mouse    73 PCVLLNYSGI-VQW---TKDGLALGMGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQ 133
            |||:.:..|. |.|   .:..:.......:...|||.:..:.:.  :.|.:..|...|...|.||
  Fly    64 PCVVEHLGGYKVAWIHIDRQMILTIHRHVISRIPRYSITYTDNT--WLLHVNQAHQDDRGYYMCQ 126

Mouse   134 ATEAALRSRRAKLTVLIPPEETRIDGGP-VILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEG 197
            .....:.|:...|.|::||....|:..| .:.::.....|:|||| :..||..|||.|    ::|
  Fly   127 VNTNPMISQVGYLQVVVPPNILDIESTPSSVAVRENQNINMTCRA-DGFPAPKIIWRR----EDG 186

Mouse   198 AVTSTELLKDGKRETTISQLLIEPTDL---------DIGRVFTCRSMNEAIPNGKETSIELDVHH 253
            ...:.|..|         ::|:...|:         ::| .:.|.:.| .:|......|.|||..
  Fly   187 EEIAVEKKK---------KVLVYDADVLPLTKVSRNEMG-AYLCIATN-GVPPSVSKRIILDVEF 240

Mouse   254 PPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFLI-------EDAHESRYET----- 306
            .|.:.:..:......|..|...|...|:|:.:.| |.....::       .|..|:.|..     
  Fly   241 SPMIWVPNQLVGAPSGTDVTIDCHTEAHPKAIIY-WVYNSVMVLPSKKYKTDYTENSYRAHMKLT 304

Mouse   307 --NVDYSFFTEPVSCEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPL 369
              |:.|..|.. ..|...|.:|.|..|.        |:...|.|:|                |..
  Fly   305 IRNLQYGDFGN-YRCISKNSLGETEGSI--------RVYEIPLPST----------------PSK 344

Mouse   370 TLTWTKKDSNMGPRLPGSPPEANLSAQV---LSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAER 431
            .:|.|..:|.....:|.|..:...|.|.   .:..|.|...|.:.:.:|..:..|          
  Fly   345 QVTHTTVESRENNIIPSSRNDTTKSLQTDVGYAMKNDLYPGSASSSSSGGSSSAA---------- 399

Mouse   432 EVPLYVNGPPIISSEAVQFAVRGD-----GGKVECFIGSTP-----PPDRIAWAWKENFLEVGTL 486
                  :....:.:.|:...|.|:     |.|....||.:.     ||:..|.:.....|    |
  Fly   400 ------SSSSSMQTSALPGGVAGNSLSSMGSKGSLAIGKSTFYTERPPNEYAASSVAGLL----L 454

Mouse   487 ERYTVERTNSGSGVLSTL 504
            .|..:    .|||:..||
  Fly   455 HRALL----FGSGIYLTL 468

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KirrelXP_011238330.1 Ig 54..148 CDD:386229 25/97 (26%)
Ig2_KIRREL3-like 170..251 CDD:143236 22/89 (25%)
Ig 255..336 CDD:386229 19/94 (20%)
Ig_3 340..421 CDD:372822 16/83 (19%)
Ig5_KIRREL3 439..536 CDD:143306 18/76 (24%)
DIP-deltaNP_001097508.2 IG 51..143 CDD:214652 23/93 (25%)
Ig 145..238 CDD:416386 25/108 (23%)
Ig strand A 145..149 CDD:409353 1/3 (33%)
Ig strand A' 154..159 CDD:409353 1/4 (25%)
Ig strand B 165..172 CDD:409353 5/7 (71%)
Ig strand C 178..183 CDD:409353 3/4 (75%)
Ig strand C' 185..187 CDD:409353 0/1 (0%)
Ig strand D 195..199 CDD:409353 1/12 (8%)
Ig strand E 203..209 CDD:409353 1/5 (20%)
Ig strand F 216..223 CDD:409353 2/7 (29%)
Ig strand G 230..238 CDD:409353 2/7 (29%)
Ig 242..333 CDD:416386 19/100 (19%)
Ig strand A' 250..253 CDD:409353 0/2 (0%)
Ig strand B 259..266 CDD:409353 2/6 (33%)
Ig strand C 272..277 CDD:409353 2/5 (40%)
Ig strand C' 281..283 CDD:409353 0/1 (0%)
Ig strand D 289..293 CDD:409353 1/3 (33%)
Ig strand E 295..305 CDD:409353 1/9 (11%)
Ig strand F 314..322 CDD:409353 1/8 (13%)
Ig strand G 325..334 CDD:409353 4/16 (25%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.900

Return to query results.
Submit another query.