DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel and CG7166

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_001262181.1	Gene:	CG7166 / 40401	FlyBaseID:	FBgn0037107	Length:	467	Species:	Drosophila melanogaster

Alignment Length:	369	Identity:	90/369 - (24%)
Similarity:	140/369 - (37%)	Gaps:	53/369 - (14%)

- Green bases have known domain annotations that are detailed below.

Mouse    26 SQKMWAPHLVVAYLIFVTLALA----------LPGTQTRFSQEPADQTVVAGQRAVLPCVLLNY- 79
            ::|.|.   :|.||...:|:|.          .|.|..:|........|:.|:...|||.:.|.
  Fly     5 TRKYWT---LVLYLFSFSLSLIGGSFILPENDPPTTAPKFLSRGHLYKVIVGETIELPCKVQNLG 66

Mouse    80 SGIVQWTKDGLALGMGQGLKAW--PRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSR 142
            |.::.|.|....|..|. ||..  .|:::|     |.|||:|...:..|...|.||..:...|.:
  Fly    67 SFVLLWRKGSSVLTAGH-LKITRDQRFKIV-----GDYNLQINGVKTQDAGDYICQLGDQENRDQ 125

Mouse   143 RAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKD 207
            ...:.:|:||....:.....:..:.|:...|.|:| :..|..||.||:     :...:....|.|
  Fly   126 VHTVEILVPPTLRALPHNGQVTARKGSTVTLECKA-SGNPVPTIFWFK-----KDVFSGPTHLSD 184

Mouse   208 GKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERV 272
            .      |.|::|..|......:.| |.:..:.:.....|:|.:..||.:|:........||..|
  Fly   185 S------STLILENVDRHHAGTYQC-SADNGVKDRVSMDIQLTILSPPEITVEKSWVHASEGYDV 242

Mouse   273 IFTC--QATANPEILGYRWAKGGFLIEDAHESR--YETNVDYSFFT---EPV-----SCEVYNKV 325
            ...|  ....|.|:|   |.:..||: ||.:.|  |..:..||...   :|.     ||...|.:
  Fly   243 ELVCIVHGDVNSEML---WYQNSFLL-DATDRRSMYPRDDRYSLIIRNFQPTDFGNYSCVADNAL 303

Mouse   326 GSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLTCVWVGNPPL 369
            |.|  ...:.|...|....:..|..:.......||......|||
  Fly   304 GRT--KKYIEVSGRPGPADFISPALSGFLDHYNLTWTIESIPPL 345

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	26/96 (27%)
		Ig2_KIRREL3-like	170..251	CDD:143236	18/80 (23%)
		Ig	255..336	CDD:386229	24/92 (26%)
		Ig_3	340..421	CDD:372822	7/30 (23%)
		Ig5_KIRREL3	439..536	CDD:143306
CG7166	NP_001262181.1	IG_like	50..133	CDD:214653	25/88 (28%)
		Ig	56..116	CDD:143165	20/65 (31%)
		IG_like	144..221	CDD:214653	19/89 (21%)
		IGc2	151..209	CDD:197706	17/70 (24%)
		IG_like	232..313	CDD:214653	22/86 (26%)
		Ig	242..311	CDD:143165	20/74 (27%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900