DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel and ImpL2

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_728961.2	Gene:	ImpL2 / 38513	FlyBaseID:	FBgn0001257	Length:	267	Species:	Drosophila melanogaster

Alignment Length:	257	Identity:	53/257 - (20%)
Similarity:	88/257 - (34%)	Gaps:	76/257 - (29%)

- Green bases have known domain annotations that are detailed below.

Mouse   241 NGKETSIELDVHHPPTVTLSIE-------PQTVL---EGERVIFTCQATANPEILGYRWAKGGFL 295
            |..:.|||.:...|.......:       |.|.|   :|..:...|:...: ::...:|..|
  Fly    35 NDVDNSIEAEEEKPRNRAFEADWLKFTKTPPTKLQQADGATIEIVCEMMGS-QVPSIQWVVG--- 95

Mouse   296 IEDAHESRYE-----------------TNVDYSFFTEPVSCE--VYNKVGSTN-----VSTLVNV 336
                |..|.|                 ..|..|...:.|..|  .|..||.|.     .||:|:.
  Fly    96 ----HLPRSELDDLDSNQVAEEAPSAIVRVRSSHIIDHVLSEARTYTCVGRTGSKTIYASTVVHP 156

Mouse   337 HFAPRI-------------VVYPKPTTTDI-GSDVTLTCVWVGNPPLTLTWTKKDSN---MGPRL 384
            ..:.|:             ::|.:.|..|: ||::.|.|.....|...:||...::.   .|.|
  Fly   157 PRSSRLTPEKTYPGAQKPRIIYTEKTHLDLMGSNIQLPCRVHARPRAEITWLNNENKEIVQGHR- 220

Mouse   385 PGSPPEANLSAQVLSNSNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSE 446
                      .:||:|.: ||:..:...|.|.|.|   :.|..|.:.....:|.  |:::.|
  Fly   221 ----------HRVLANGD-LLISEIKWEDMGNYKC---IARNVVGKDTADTFVY--PVLNEE 266

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229
		Ig2_KIRREL3-like	170..251	CDD:143236	4/9 (44%)
		Ig	255..336	CDD:386229	21/114 (18%)
		Ig_3	340..421	CDD:372822	22/97 (23%)
		Ig5_KIRREL3	439..536	CDD:143306	2/8 (25%)
ImpL2	NP_728961.2	IGc2	187..251	CDD:197706	19/78 (24%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.900