DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel and dpr19

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_001260336.1	Gene:	dpr19 / 34408	FlyBaseID:	FBgn0032233	Length:	385	Species:	Drosophila melanogaster

Alignment Length:	185	Identity:	44/185 - (23%)
Similarity:	74/185 - (40%)	Gaps:	21/185 - (11%)

- Green bases have known domain annotations that are detailed below.

Mouse    25 LSQKMWAPHLVVAYLIFVTLALA----LPGTQTRFSQEPADQ-------TVVA--GQRAVLPCVL 76
            :..|.|..|| ..:|:.::...:    :..:|..|......|       .|:|  |..|:||||:
  Fly     1 MEPKRWHLHL-SCFLLLLSSTFSDVGKITSSQNHFGNTLQSQFNTKNNTRVIAQKGGLAILPCVV 64

Mouse    77 -LNYSGIVQW--TKDGLALGMGQGL-KAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEA 137
             :|....|.|  .||...|.:|... .:..|:.|..:...|.::|.|......|...||||.:..
  Fly    65 KVNSPATVSWIRRKDFQLLTVGLSTHSSDKRFLVEHTRHMGHWSLRIKAVREEDRGFYECQLSIY 129

Mouse   138 ALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRAFNA-KPAATIIWFRD 191
            ..:|...:|.::....|  |...|.:.:...:...|.|:...| :..|.:.|:.|
  Fly   130 PTQSIVIELKIVEAVAE--ISSAPELHIDETSTLRLECKLKRATENPAFVFWYHD 182

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	29/106 (27%)
		Ig2_KIRREL3-like	170..251	CDD:143236	6/23 (26%)
		Ig	255..336	CDD:386229
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
dpr19	NP_001260336.1	IG_like	50..127	CDD:214653	25/76 (33%)
dpr19	NP_001260336.1	IGc2	55..125	CDD:197706	21/69 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810