DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel and DIP-iota

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_001097100.1	Gene:	DIP-iota / 33925	FlyBaseID:	FBgn0031837	Length:	376	Species:	Drosophila melanogaster

Alignment Length:	317	Identity:	72/317 - (22%)
Similarity:	129/317 - (40%)	Gaps:	47/317 - (14%)

- Green bases have known domain annotations that are detailed below.

Mouse    48 LPGTQTRFSQEPADQTVVAGQRAVLPCV---LLNYSGIVQWTK-DGLALGMGQGLKAWPRYRV-V 107
            |..:..:||....:.||..|:.|:|.||   |:::.  |.|.: |...:...|.......:|: :
  Fly    26 LNNSDPKFSGPINNSTVPVGRDALLTCVVHDLVSFK--VAWLRVDTQTILSIQNHVITKNHRISI 88

Mouse   108 GSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRIDGGPVILLQAGTPYN 172
            ...:...:.|:|.|.:.||...|.||.....::|:...|.|::||:.........::...|....
  Fly    89 SHTEHRIWQLKIRDVQESDRGWYMCQINTDPMKSQMGYLDVVVPPDIVDYQTSQDVVRSTGQNVT 153

Mouse   173 LTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTISQLLIEPTDLDIGRV-------F 230
            |||.| ...|..||.|.|:      ..|...:..||.||.    ..:|..:|.:.:|       :
  Fly   154 LTCSA-TGVPMPTITWRRE------EATPILISDDGDREV----FSVEGQNLTLWQVQRSHMGAY 207

Mouse   231 TCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGERVIFTCQATANPEILGYRWAKGGFL 295
            .|.:.| .:|......:.|.|:..||:....:...|..|:::...|...:.|..:.: |.:...|
  Fly   208 LCIASN-GVPPTVSKRVMLVVNFAPTIWTRYDTIYVGLGQKLTLECITESQPASVNF-WLRDSQL 270

Mouse   296 IE-DAHESRYETNVDYSF------FTEPVS--------CEVYNKVGSTNVSTLVNVH 337
            :: .::||   .:||:.|      ...|::        |...|.:|.|:  .::.||
  Fly   271 LQGGSYES---VSVDHVFRIVMRITLRPITKRDFGEYICRAKNAMGQTD--RIITVH 322

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	25/98 (26%)
		Ig2_KIRREL3-like	170..251	CDD:143236	21/87 (24%)
		Ig	255..336	CDD:386229	18/95 (19%)
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
DIP-iota	NP_001097100.1	IG_like	39..125	CDD:214653	22/87 (25%)
		Ig	39..122	CDD:299845	21/84 (25%)
		Ig	132..213	CDD:299845	21/91 (23%)
		IG_like	141..227	CDD:214653	22/97 (23%)
		IG_like	239..322	CDD:214653	16/88 (18%)
		IGc2	245..313	CDD:197706	13/71 (18%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810