DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Kirrel and dpr4

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_001014616.2	Gene:	dpr4 / 3346160	FlyBaseID:	FBgn0053512	Length:	323	Species:	Drosophila melanogaster

Alignment Length:	238	Identity:	59/238 - (24%)
Similarity:	98/238 - (41%)	Gaps:	64/238 - (26%)

- Green bases have known domain annotations that are detailed below.

Mouse    52 QTRFSQEPADQ------TVVAGQRAVLPCVLLNYS-----------------GIVQWTKDGLALG 93
            :|.:||...|.      |...||.|:|.|.:.|..                 ||:.:|.|
  Fly    39 ETPYSQPYFDNSSRREVTATVGQAALLHCRVRNLGDRAVSWIRKRDLHILTVGILTYTND----- 98

Mouse    94 MGQGLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEETRID 158
                    .|::.:.|..:.::.|.|:..:..|..:||||.:.....|:..:|.|::  ...:|.
  Fly    99 --------QRFQSLHSEGSDEWTLRISSPQPRDSGTYECQVSTEPKISQGFRLNVVV--SRAKIL 153

Mouse   159 GGPVILLQAGTPYNLTCRAFNAK-PAATIIWFR-----DGTQQEGAVTSTELLKDGKRETTISQL 217
            |...:.:::|:..||||.|..:. |.:.|.|::     :.:|:.|....||      |.|..|:|
  Fly   154 GNAELFIKSGSDINLTCLAMQSPVPPSFIYWYKGKRVMNYSQRGGINVITE------RSTRTSKL 212

Mouse   218 LI-EPTDLDIGRVFTCRSMNEAIPNGKETSIELDVH-----HP 254
            || :.|..|.|. :||.      |:..: |..:.||     ||
  Fly   213 LIAKATPADSGN-YTCS------PSSSD-SASVVVHVINGEHP 247

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	25/116 (22%)
		Ig2_KIRREL3-like	170..251	CDD:143236	25/87 (29%)
		Ig	255..336	CDD:386229	59/238 (25%)
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
dpr4	NP_001014616.2	V-set	53..146	CDD:284989	22/105 (21%)
		IG_like	53..145	CDD:214653	22/104 (21%)
		ig	153..227	CDD:278476	23/80 (29%)
		IG_like	161..>227	CDD:214653	22/72 (31%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810