DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel and dpr18

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_573102.1	Gene:	dpr18 / 32572	FlyBaseID:	FBgn0030723	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	301	Identity:	59/301 - (19%)
Similarity:	102/301 - (33%)	Gaps:	97/301 - (32%)

- Green bases have known domain annotations that are detailed below.

Mouse   173 LTCRAFNAKPAATIIWFRDGTQQEGAVTSTELLKDGKRETTIS-------QLLIEPTDLDIGRVF 230
            |.||....|. .|::|.|...::...:|...:...|.....:.       :|||.||..:...|:
  Fly   244 LNCRVGMLKD-KTVMWVRRTAEKVSLLTVGNVTYSGDPRIRVKFQYPNNWRLLINPTQTEDAGVY 307

Mouse   231 TCRSMNEAIPNGKETSIELDVHHPPTVTLSIEPQTVLEGE-RVIFTCQATANPEILGYRWAKGGF 294
            .|               ::..|.|...|.::   ||||.. |:|     ..:...:|.|:.|.|.
  Fly   308 MC---------------QVSTHPPRVFTTNL---TVLEPPLRII-----DEHERDVGDRYYKSGS 349

Mouse   295 LIEDAHESRYETNVDYSFFTEPVSCEVYNKVGSTN--VSTLVNVHFAPRIVVYPKPTTTDIGSDV 357
            .::      .:..:..|||.:... .:.....|.|  |..|:|            .||:::.
  Fly   350 TVD------LQCQISRSFFQKERQ-TILKSTDSANDAVQKLIN------------ETTSELN--- 392

Mouse   358 TLTCVWVGNPPLT----------------LTWTKKDSNMGPRLPGSPPEANLSAQVLSNSNQLLL 406
                 .:||...|                :||.|.:.          |...::.:.||.|:..|.
  Fly   393 -----LIGNVNQTQHKFSGQDLEKYFTKFITWAKDEE----------PLQGMTNRRLSVSDVWLT 442

Mouse   407 KSVTQADA-----GTYTCR-----AIVPRIGVAEREVPLYV 437
            ..::..||     |.|:|.     .::.::.|...|:|..|
  Fly   443 SRISIGDAKLSDSGNYSCSLGRLFTVIVQVQVLTGELPAAV 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229
		Ig2_KIRREL3-like	170..251	CDD:143236	16/84 (19%)
		Ig	255..336	CDD:386229	18/83 (22%)
		Ig_3	340..421	CDD:372822	18/106 (17%)
		Ig5_KIRREL3	439..536	CDD:143306
dpr18	NP_573102.1	IG_like	242..325	CDD:214653	19/99 (19%)
		Ig	<258..326	CDD:299845	15/85 (18%)
		IGc2	<417..461	CDD:197706	12/53 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810