DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Kirrel and dpr8

DIOPT Version :9

Sequence 1:	XP_011238330.1	Gene:	Kirrel / 170643	MGIID:	1891396	Length:	805	Species:	Mus musculus
Sequence 2:	NP_001285239.1	Gene:	dpr8 / 32387	FlyBaseID:	FBgn0052600	Length:	344	Species:	Drosophila melanogaster

Alignment Length:	281	Identity:	68/281 - (24%)
Similarity:	105/281 - (37%)	Gaps:	48/281 - (17%)

- Green bases have known domain annotations that are detailed below.

Mouse    33 HLVVAYLIFVTLALALPGTQTRFSQE------------PADQTVV-------AGQRAVLPCVLLN 78
            |.::...|...||....|...||..:            |...|.:       .|:...|.|.:.|
  Fly     4 HWIIFLGILCLLAGCTDGASKRFFTDFLQDLPTPGTGGPTFDTTIGTNITGLVGKTVKLTCRVKN 68

Mouse    79 YSG-IVQWT--KDGLALGMGQ-GLKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAAL 139
            ... .|.|.  :|...|.:|: ...:..|:..:.|..|..:.|.|..|:..|...||||.:....
  Fly    69 LGNRTVSWVRHRDIHLLTVGRYTYTSDQRFEAMHSPHAEDWTLRIRYAQRKDSGIYECQISTTPP 133

Mouse   140 RSRRAKLTVLIPPEETRIDGGPVILLQAGTPYNLTCRA-FNAKPAATIIWFRD------GTQQEG 197
            ......|.::.|  .|.|.|||.:.:..|:..||||.. |..:|..|:||..:      .:.:.|
  Fly   134 IGHSVYLNIVEP--VTDIIGGPELHINRGSTINLTCIVKFAPEPPPTVIWSHNREIINFDSPRGG 196

Mouse   198 AVTSTELLKDGKRETTISQLLIEPTDLDIGRVFTCRSMNEAIPNGKETSIELDVHHPPTV----- 257
            ....||     |...|.|:||::........::||...| |.|......| :|..||..:
  Fly   197 ISLVTE-----KGVLTTSRLLVQKAITQDSGLYTCTPSN-ANPTSVRVHI-VDGEHPAAMHTGNN 254

Mouse   258 --TLSIEPQTVLEGERVIFTC 276
              :.:.:|..:|  ..|:.||
  Fly   255 GNSTASQPPVLL--PLVLLTC 273

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Kirrel	XP_011238330.1	Ig	54..148	CDD:386229	25/116 (22%)
		Ig2_KIRREL3-like	170..251	CDD:143236	23/87 (26%)
		Ig	255..336	CDD:386229	5/29 (17%)
		Ig_3	340..421	CDD:372822
		Ig5_KIRREL3	439..536	CDD:143306
dpr8	NP_001285239.1	IG_like	51..131	CDD:214653	20/79 (25%)
		V-set	52..143	CDD:284989	21/90 (23%)
		IG_like	153..238	CDD:214653	24/90 (27%)
		ig	153..232	CDD:278476	22/84 (26%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810