DRSC/TRiP Functional Genomics Resources

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Protein Alignment Kirrel and Dscam4

DIOPT Version :9

Sequence 1:XP_011238330.1 Gene:Kirrel / 170643 MGIID:1891396 Length:805 Species:Mus musculus
Sequence 2:NP_001261571.1 Gene:Dscam4 / 2769008 FlyBaseID:FBgn0263219 Length:1935 Species:Drosophila melanogaster


Alignment Length:578 Identity:144/578 - (24%)
Similarity:229/578 - (39%) Gaps:104/578 - (17%)


- Green bases have known domain annotations that are detailed below.


Mouse    17 LLPEKPRFLSQKMWA--PHLVVAYLIFV---------TLALALPGTQTRFSQEPADQTVVAGQRA 70
            :|.:.||.:.:|:..  |.:   |..||         |..|.|...........::||:..|...
  Fly   378 ILTDPPRLIIKKVQKEDPGM---YQCFVSNEWEQIQSTAELQLGDASPELLYWFSEQTLQPGPTV 439

Mouse    71 VLPCVLL-NYSGIVQWTKDGLALGMGQGLKAWPRYRVVGSADAGQY---------NLEITDAELS 125
            .|.||.. |......|:.||..:....      |:.|      |||         ::.|::.:..
  Fly   440 SLKCVATGNPLPQFTWSLDGFPIPDSS------RFLV------GQYVTIHDDVISHVNISNVKEE 492

Mouse   126 DDASYECQATEAALR-SRRAKLTVL-IP-----PEETRIDGGPVILLQAGTPYNLTCRAFNAKPA 183
            |...|.|.|..|..: |..||:.:. :|     |:.|.|.|..:|:......|          |.
  Fly   493 DGGEYTCTAQNAIGKVSHSAKVNIYGLPYIREMPKITGISGSDLIVKCPVAGY----------PI 547

Mouse   184 ATIIWFRDGTQQEGAVTSTELLKDGKRETTISQ--LLIEPTD-LDIGRVFTCRSMNEAIPNGKET 245
            ..|.|.|||          :.|...:|:...:.  |:||... |:....:||.:.|:.    |:|
  Fly   548 DKIHWERDG----------QTLPINRRQRAYNNGTLIIEQLQRLEDAGTYTCMAQNKQ----KQT 598

Mouse   246 S---IELDVHHPPTVTLSIEPQT--VLEGERVIFTCQATANPEILGYRWAKGGF-LIEDAHE-SR 303
            |   :|:.|..||.: :.|:..|  :.||.|...:||.......:.:||.:.|. ||...:| .|
  Fly   599 SRRNVEIQVLVPPKI-MPIQAMTNMLREGMRAAISCQILEGDLPVSFRWERNGKPLIGTGNEVFR 662

Mouse   304 YETNVDYSFFTEPVS--------CEVYNKVGSTNVSTLVNVHFAPRIVVYPKPTTTDIGSDVTLT 360
            .......|...|.:|        |...|..|:...:..:.|:..|:.::.||.::...|:||.|.
  Fly   663 RLDEYSASLVIEHISSDHSGNYTCIASNVAGTERFTVPLTVNVPPKWILEPKDSSAQAGADVLLH 727

Mouse   361 CVWVGNPPLTLTWTKKDSNMGPRLPGSPPE--ANLSAQVLSNSNQLLLKSVTQADAGTYTCRAIV 423
            |...|.|..|:||.|.   :|| .||...:  ...:.|:..|.. :..|.:::...|.:.|.| .
  Fly   728 CQSSGYPTPTITWKKA---IGP-TPGEYKDFLYEPTVQLFPNGT-IFFKKISKESQGHFLCEA-K 786

Mouse   424 PRIGV-AEREVPLYVNGPPIISSEAVQFAV-RGDGGKVECFIGSTPPPDRIAWAWK----ENFLE 482
            ..||. ..:.:.|.||.|....::..|.:| :|....|:|.:....|.|   :.||    :.:|:
  Fly   787 NNIGSGVSKVIFLKVNVPAHFQTKTKQISVAKGKQVHVQCNVQGDNPID---FKWKIQATQQYLD 848

Mouse   483 VGTLERYTVERTNSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEEREV 540
            .....|||:.......|::|.|.|::....|... |.|.|.|:||.....|||..:||
  Fly   849 ESLDSRYTIRDQVLDDGMVSELGISHTYRQDTGI-YICQASNAFGQDEMSIQLIVQEV 905

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KirrelXP_011238330.1 Ig 54..148 CDD:386229 24/104 (23%)
Ig2_KIRREL3-like 170..251 CDD:143236 20/86 (23%)
Ig 255..336 CDD:386229 21/92 (23%)
Ig_3 340..421 CDD:372822 23/82 (28%)
Ig5_KIRREL3 439..536 CDD:143306 27/101 (27%)
Dscam4NP_001261571.1 Ig 31..124 CDD:416386
Ig strand A 32..35 CDD:409353
Ig strand A' 41..45 CDD:409353
Ig strand B 48..57 CDD:409353
Ig strand D 75..78 CDD:409353
Ig strand E 83..88 CDD:409353
Ig strand F 101..109 CDD:409353
Ig strand G 112..124 CDD:409353
Ig 235..326 CDD:416386
Ig strand A 235..238 CDD:409353
Ig strand A' 244..248 CDD:409353
Ig strand B 251..258 CDD:409353
Ig strand C 266..271 CDD:409353
Ig strand C' 276..279 CDD:409353
Ig strand D 285..289 CDD:409353
Ig strand E 292..298 CDD:409353
Ig strand F 305..313 CDD:409353
Ig strand G 316..326 CDD:409353
IgC2_3_Dscam 329..417 CDD:409549 10/41 (24%)
Ig strand B 347..351 CDD:409549
Ig strand C 360..364 CDD:409549
Ig strand E 383..387 CDD:409549 2/3 (67%)
Ig strand F 397..402 CDD:409549 1/7 (14%)
Ig strand G 410..413 CDD:409549 0/2 (0%)
IgI_4_Dscam 422..516 CDD:409548 24/105 (23%)
Ig strand B 439..443 CDD:409548 1/3 (33%)
Ig strand C 452..456 CDD:409548 0/3 (0%)
Ig strand E 482..486 CDD:409548 0/3 (0%)
Ig strand F 496..501 CDD:409548 2/4 (50%)
Ig strand G 509..512 CDD:409548 1/2 (50%)
IgI_5_Dscam 520..607 CDD:409550 26/110 (24%)
Ig strand B 536..540 CDD:409550 1/3 (33%)
Ig strand C 549..553 CDD:409550 1/3 (33%)
Ig strand E 571..575 CDD:409550 1/3 (33%)
Ig strand F 586..591 CDD:409550 2/4 (50%)
Ig strand G 600..603 CDD:409550 0/2 (0%)
Ig 610..703 CDD:416386 22/93 (24%)
Ig strand A 611..613 CDD:409353 1/1 (100%)
Ig strand A' 620..624 CDD:409353 1/3 (33%)
Ig strand B 627..636 CDD:409353 3/8 (38%)
Ig strand C 641..648 CDD:409353 2/6 (33%)
Ig strand C' 650..652 CDD:409353 1/1 (100%)
Ig strand D 659..664 CDD:409353 2/4 (50%)
Ig strand E 668..675 CDD:409353 1/6 (17%)
Ig strand F 682..690 CDD:409353 1/7 (14%)
Ig strand G 693..702 CDD:409353 1/8 (13%)
IgI_7_Dscam 706..801 CDD:409546 27/100 (27%)
Ig strand B 724..728 CDD:409546 2/3 (67%)
Ig strand C 737..741 CDD:409546 2/3 (67%)
Ig strand E 766..770 CDD:409546 0/4 (0%)
Ig strand F 780..785 CDD:409546 1/4 (25%)
Ig strand G 794..797 CDD:409546 0/2 (0%)
Ig 818..904 CDD:416386 25/89 (28%)
putative Ig strand B 820..827 CDD:409353 1/6 (17%)
putative Ig strand C 835..841 CDD:409353 3/8 (38%)
putative Ig strand C' 853..856 CDD:409353 1/2 (50%)
putative Ig strand D 862..866 CDD:409353 0/3 (0%)
putative Ig strand E 868..874 CDD:409353 3/5 (60%)
putative Ig strand F 881..889 CDD:409353 3/8 (38%)
putative Ig strand G 892..902 CDD:409353 4/9 (44%)
FN3 906..999 CDD:238020 144/578 (25%)
FN3 1006..1110 CDD:238020
fn3 1117..1203 CDD:394996
FN3 1215..1307 CDD:238020
Ig <1334..1401 CDD:416386
Ig strand C 1345..1349 CDD:409353
Ig strand D 1363..1366 CDD:409353
Ig strand E 1367..1372 CDD:409353
Ig strand F 1380..1388 CDD:409353
Ig strand G 1394..1401 CDD:409353
FN3 1405..1494 CDD:238020
FN3 1499..1580 CDD:238020
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 1 1.000 54 1.000 Domainoid score I11159
eggNOG 1 0.900 - - E1_KOG3510
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
32.810

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