DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lum and CG18095

DIOPT Version :9

Sequence 1:NP_032550.2 Gene:Lum / 17022 MGIID:109347 Length:338 Species:Mus musculus
Sequence 2:NP_001188805.1 Gene:CG18095 / 34823 FlyBaseID:FBgn0028872 Length:564 Species:Drosophila melanogaster


Alignment Length:238 Identity:77/238 - (32%)
Similarity:116/238 - (48%) Gaps:41/238 - (17%)


- Green bases have known domain annotations that are detailed below.


Mouse    68 IKYLYLRNNQIDHIDEKAFENVTDLQWLILDHNLLE---------NSKIKG-----KVFSKLKQL 118
            :|:|||..||:.|||...|..:..|..|.|.||.:|         |:.::.     .:.|.|:.|
  Fly   161 LKHLYLNGNQLAHIDGSFFRGLHRLSSLSLQHNRIEFIEMDSFESNTHLRSLRLDQNLLSSLQFL 225

Mouse   119 KK------LHINY-NNLTESVGPLPKS----LQDLQLTNNKISKLG--SFDGLVNLTFIYLQHNQ 170
            .:      :|:|. :||.:.:.|...|    ||||.|:.|.|:||.  :..||.:|..:.:.||.
  Fly   226 SQRGLARLVHLNLSSNLLQKLEPFVFSKNFELQDLDLSYNNITKLNKEALSGLDSLERLNISHNY 290

Mouse   171 LKEDAVSASLKGLKSLEYLDLSFNQMSKLPAGL---PTSLLTLYLDNNKISNIPDEYFKRFTGLQ 232
            : :.....||..|.:|..||:|||.::.||..|   .|.|..:.|.||||..|..:.......|:
  Fly   291 V-DKIYDESLDSLIALLQLDISFNLLTTLPDNLFHFNTQLEEIILANNKIEEISSQMMFNQNHLR 354

Mouse   233 YLRLSHNELADSGV-----PG-NSFNISSLLELDLSYNKLKSI 269
            |::||.|.::|:..     |. |.|.    |.:|||.|:|||:
  Fly   355 YIKLSGNAISDAAFLDRLSPSVNRFT----LYVDLSSNRLKSL 393

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
LumNP_032550.2 LRRNT 37..71 CDD:214470 1/2 (50%)
LRR_RI <66..267 CDD:238064 74/234 (32%)
LRR_8 66..128 CDD:290566 22/80 (28%)
LRR 1 67..88 10/19 (53%)
leucine-rich repeat 68..91 CDD:275380 10/22 (45%)
LRR 2 91..114 7/36 (19%)
leucine-rich repeat 92..117 CDD:275380 9/38 (24%)
LRR_8 116..171 CDD:290566 21/67 (31%)
LRR 3 117..137 6/26 (23%)
leucine-rich repeat 118..138 CDD:275380 6/26 (23%)
LRR 4 138..159 11/26 (42%)
leucine-rich repeat 139..160 CDD:275380 11/22 (50%)
LRR_8 160..217 CDD:290566 20/59 (34%)
LRR 5 160..181 4/20 (20%)
leucine-rich repeat 161..185 CDD:275380 6/23 (26%)
LRR 6 185..205 9/22 (41%)
leucine-rich repeat 186..206 CDD:275380 9/22 (41%)
LRR_8 205..266 CDD:290566 22/66 (33%)
LRR 7 206..227 7/20 (35%)
leucine-rich repeat 207..230 CDD:275380 7/22 (32%)
LRR 8 230..250 7/25 (28%)
leucine-rich repeat 231..255 CDD:275380 9/29 (31%)
LRR 9 255..276 8/15 (53%)
leucine-rich repeat 276..305 CDD:275380
LRR 10 277..296
LRR 11 305..326
leucine-rich repeat 306..329 CDD:275380
CG18095NP_001188805.1 leucine-rich repeat 41..64 CDD:275380
LRR_8 64..123 CDD:290566
leucine-rich repeat 65..88 CDD:275380
leucine-rich repeat 89..112 CDD:275380
leucine-rich repeat 113..136 CDD:275380
LRR_RI 115..384 CDD:238064 70/227 (31%)
LRR_8 135..195 CDD:290566 15/33 (45%)
leucine-rich repeat 137..160 CDD:275380
leucine-rich repeat 161..184 CDD:275380 10/22 (45%)
LRR_8 184..243 CDD:290566 13/58 (22%)
leucine-rich repeat 185..208 CDD:275380 7/22 (32%)
leucine-rich repeat 209..232 CDD:275380 3/22 (14%)
LRR_8 232..289 CDD:290566 18/56 (32%)
leucine-rich repeat 233..256 CDD:275380 6/22 (27%)
leucine-rich repeat 257..280 CDD:275380 11/22 (50%)
LRR_8 280..339 CDD:290566 20/59 (34%)
leucine-rich repeat 281..304 CDD:275380 6/23 (26%)
leucine-rich repeat 305..328 CDD:275380 9/22 (41%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45712
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
11.100

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