Protein Alignment GLIS3 and iec1

DIOPT Version :9

• Sequence 1: NP_001035878.1
• Gene: GLIS3 / 169792
• HGNCID: 28510
• Length: 930
• Species: Homo sapiens
• Sequence 2: NP_594663.1
• Gene: iec1 / 2542854
• PomBaseID: SPAC144.02
• Length: 249
• Species: Schizosaccharomyces pombe
• Alignment Length: 212
• Identity: 53/212 - (25%)
• Similarity: 80/212 - (37%)
• Gaps: 73/212 - (34%)

Human   481 ALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVRHIEK----------------VHIDQR 529
            ::|.:.:|.:.|.:.|     |.|..|.......:.||.||..                .||..|
pombe    10 SVPGSPIDLEPESETI-----CHWQSCEQDLLTLDNLVHHIHNGTTSNLRLISNINSILDHIGNR 69

Human   530 KGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENLKIHLRSHTGE 594
            :.: :||.|..|||:.....:|:.|:                              .||||||||
pombe    70 RPK-YTCEWDDCPRKGMVQTSRFALV------------------------------AHLRSHTGE 103

Human   595 KPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVKAHSSKEQ--- 656
            ||::|..|.|.::|:.|...|||.||..:..         |.|.:||..     |||....|
pombe   104 KPFICSVPECDRSFTRSDALAKHMRTVHEAD---------TLRPSDPIP-----KAHPMHPQNVA 154

Human   657 ----QARKKLRSSTELH 669
                |:.::.|:..::|
pombe   155 NAMVQSAREARAQQQMH 171

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLIS3	NP_001035878.1	zf-H2C2_2	554..580	CDD:290200	1/25 (4%)
		C2H2 Zn finger	569..591	CDD:275368	3/21 (14%)
		zf-H2C2_2	583..610	CDD:290200	14/26 (54%)
		C2H2 Zn finger	599..621	CDD:275368	9/21 (43%)
		C2H2 Zn finger	629..651	CDD:275368	5/21 (24%)
iec1	NP_594663.1	COG5048	1..>249	CDD:227381	53/212 (25%)
		zf-H2C2_2	92..119	CDD:290200	15/56 (27%)
		C2H2 Zn finger	108..129	CDD:275368	8/20 (40%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R588
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	1.030