Protein Alignment GLIS3 and Glis3

DIOPT Version :10

• Sequence 1: NP_001035878.1
• Gene: GLIS3 / 169792
• HGNCID: 28510
• Length: 930
• Species: Homo sapiens
• Sequence 2: NP_780668.3
• Gene: Glis3 / 226075
• MGIID: 2444289
• Length: 935
• Species: Mus musculus
• Alignment Length: 937
• Identity: 785/937 - (83%)
• Similarity: 831/937 - (88%)
• Gaps: 9/937 - (0%)

Human     1 MNGRSCSMSLHRTSGTPQGPRMVSGHHIPAIRAHSGTPGPSPCGSTSSPTMASLANNLHLKMPSG 65
            ||||||.|:|||||.|||||.::.|.|||.||||:|||..|.|.||.||::.||||:|||||.||
Mouse     1 MNGRSCGMNLHRTSRTPQGPGLLGGQHIPPIRAHAGTPCSSSCASTPSPSIGSLANSLHLKMSSG 65

Human    66 GGMAPQNNVAESRIHLPALSPRRQMLTNGKPRFQVTQAGGMSGSHTLKPKQQEFGSPFPPNPGKG 130
            .|||||:|:|.|.|||||||||||:|.||||:||||.||.|:..||:||||||||.||.|||.||
Mouse    66 AGMAPQSNMAASPIHLPALSPRRQLLANGKPQFQVTPAGVMAAPHTIKPKQQEFGDPFSPNPEKG 130

Human   131 ALGFGPQCKSIGKGSCNNLVVTSSPMMVQRLGLISPPASQVSTACNQISPSLQRAMNAANLNIPP 195
            ||||||||||||||||||||||||||||||||.||||||||||||.||||||.||:||||||.||
Mouse   131 ALGFGPQCKSIGKGSCNNLVVTSSPMMVQRLGPISPPASQVSTACKQISPSLPRAVNAANLNRPP 195

Human   196 SDTRSLISRESLASTTLSLTESQSASSMKQEWSQGYRALPSL-SNHGSQNGLDLGDLLSLPPGTS 259
            |||||:|.:|||.||||||||||||.|:||||||.|||.||| |:|.||||.||||||||||||.
Mouse   196 SDTRSVILQESLVSTTLSLTESQSALSVKQEWSQSYRAFPSLSSSHSSQNGTDLGDLLSLPPGTP 260

Human   260 MSSNSVSNSLPSYLFGTESSHSPYPSPRHSSTRSHSARSKKRALSLSPLSDGIGIDFNTIIRTSP 324
            :|.||||||||.||||.|:|||||||||||:||:||.||||||||||||||||||||||||||||
Mouse   261 VSGNSVSNSLPPYLFGMENSHSPYPSPRHSATRAHSTRSKKRALSLSPLSDGIGIDFNTIIRTSP 325

Human   325 TSLVAYINGSRASPANLSPQPEVYGHFLGVRGSCIPQPRPVPGSQKGVLVAPGGLALPAYGEDGA 389
            |||||||||.||||||||||.||||||||||||||||...|...|||:|||.||..||.|||||.
Mouse   326 TSLVAYINGPRASPANLSPQSEVYGHFLGVRGSCIPQSCAVASGQKGILVASGGHTLPGYGEDGT 390

Human   390 LEHERMQQLEHGGLQPGLVNHMVVQHGLPGPDSQSAGLFKTERLEEFPGSTVDLPPAPPLPPLPP 454
            ||:||||||||||||||.||:||:|.||||.|.|:|.:.|||||||||.|.:|||.|.|| ||||
Mouse   391 LEYERMQQLEHGGLQPGPVNNMVLQPGLPGQDGQTANMLKTERLEEFPASALDLPSALPL-PLPP 454

Human   455 PPGPPPPYHAHAHLHHPELGPHAQQLALPQATLDDDGEMDGIGGKHCCRWIDCSALYDQQEELVR 519
            |.|||||||||.|||||||.||.|.|:|.|..|::||||:..|||||||||||||||||||||||
Mouse   455 PQGPPPPYHAHPHLHHPELLPHTQSLSLAQTGLEEDGEMEDSGGKHCCRWIDCSALYDQQEELVR 519

Human   520 HIEKVHIDQRKGEDFTCFWAGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCEKAFSRLENL 584
            |||||||||||||||||||.|||||||||||||||||||||||||||||||||||:|||||||||
Mouse   520 HIEKVHIDQRKGEDFTCFWTGCPRRYKPFNARYKLLIHMRVHSGEKPNKCTFEGCKKAFSRLENL 584

Human   585 KIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVK 649
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   585 KIHLRSHTGEKPYLCQHPGCQKAFSNSSDRAKHQRTHLDTKPYACQIPGCTKRYTDPSSLRKHVK 649

Human   650 AHSSKEQQARKKLRSSTELHPDLLTDCLTVQSLQPATSPRDAAAEGTVGRSPGPGP------DLY 708
            ||||:|||||||||||||||||||||||.||.|||||||.| ||:.|||.||||||      :||
Mouse   650 AHSSREQQARKKLRSSTELHPDLLTDCLAVQPLQPATSPGD-AADHTVGHSPGPGPGPGPGAELY 713

Human   709 SAPIFSSNYSSRSGTAAGAVPPPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPSAPS 773
            |||||:||:|:||||||||.|||||||||||||||||||||||||||||||||||||||||..||
Mouse   714 SAPIFASNHSTRSGTAAGAGPPPHPVSHPSPGHNVQGSPHNPSSQLPPLTAVDAGAERFAPPTPS 778

Human   774 PHHISPRRVPAPSSILQRTQPPYTQQPSGSHLKSYQPETNSSFQPNGIHVHGFYGQLQKFCPPHY 838
            ||||||.|||||.|:|||.|.|::|||.||.||.||||||||||||||||||||||||.||||||
Mouse   779 PHHISPGRVPAPPSLLQRAQAPHSQQPPGSLLKPYQPETNSSFQPNGIHVHGFYGQLQTFCPPHY 843

Human   839 PDSQRIVPPVSSCSVVPSFEDCLVPTSMGQASFDVFHRAFSTHSGITVYDLPSSSSSLFGESLRS 903
            |||||.|||..|||:||||||||||||||||.|||||||||||||||||||||:|||||||||||
Mouse   844 PDSQRTVPPSGSCSMVPSFEDCLVPTSMGQAGFDVFHRAFSTHSGITVYDLPSASSSLFGESLRS 908

Human   904 GAEDATFLQISTVDRCPSQLSSVYTEG 930
            |.||.||||:|.|||||||||||||||
Mouse   909 GPEDPTFLQLSAVDRCPSQLSSVYTEG 935

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
GLIS3	NP_001035878.1	SFP1	<558..652	CDD:227516	92/93 (99%)
		C2H2 Zn finger	569..591	CDD:275368	20/21 (95%)
		C2H2 Zn finger	599..621	CDD:275368	21/21 (100%)
		C2H2 Zn finger	629..651	CDD:275368	21/21 (100%)
Glis3	NP_780668.3	C2H2 Zn finger	506..525	CDD:275368	18/18 (100%)
		C2H2 Zn finger	536..561	CDD:275368	23/24 (96%)
		SFP1	<558..652	CDD:227516	92/93 (99%)
		C2H2 Zn finger	569..591	CDD:275368	20/21 (95%)
		C2H2 Zn finger	599..621	CDD:275368	21/21 (100%)
		PHA03247	<612..861	CDD:223021	213/249 (86%)
		C2H2 Zn finger	629..651	CDD:275368	21/21 (100%)