DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrrc23 and Cep97

DIOPT Version :9

Sequence 1:XP_006505721.1 Gene:Lrrc23 / 16977 MGIID:1315192 Length:370 Species:Mus musculus
Sequence 2:NP_608811.2 Gene:Cep97 / 33610 FlyBaseID:FBgn0031575 Length:806 Species:Drosophila melanogaster


Alignment Length:288 Identity:74/288 - (25%)
Similarity:117/288 - (40%) Gaps:61/288 - (21%)


- Green bases have known domain annotations that are detailed below.


Mouse    95 AHAYIKLEAKDRDLTDISLLRSYIHLRYVDISENHITDISPLNSLTHLLWLKADGNQLRSARMNE 159
            ||:..:|...:.:|..|..:.||:.:..:.::.|.:                     ||...:..
  Fly    29 AHSIRQLILDENELQKIDNIDSYLKIETLSLARNQL---------------------LRMYGVCR 72

Mouse   160 LPYLQIASFSYNQIIDTEGI---FHPRLGSLDLKGNRIHQVTGLDPERLSSLHTLELRGNQLEST 221
            |..|:..:.|:|.|:..||:   .|.|:  |:|:||.|..:..|:..  .:|..|.|..|.:.|.
  Fly    73 LHCLRELNLSFNGILSIEGLKECIHLRV--LNLEGNNIKTIEHLNTN--VNLECLNLADNSIGSI 133

Mouse   222 KGI-YLPKLKNLYLAQNLLKKVEGLENLSNLTTLHLR--DNQIETLNGFSQEMKSLQYLNLRSNM 283
            ..: ||..||.|||..|.|              .|||  |..:.|         ||:.|.|..|.
  Fly   134 SDMSYLRNLKELYLHGNRL--------------THLRQCDKCLPT---------SLETLTLAKNS 175

Mouse   284 ISDLAELAKLRDLPKLRALVLLDNPCA------DETDYRQEALVQMAHLERLDKEFYEDDDRAEA 342
            |:||.|:..|..|..|.::.:.||||.      |..|||...|.....|:.:|....:..:..:|
  Fly   176 INDLNEICTLSHLSNLLSISIADNPCVTMINSLDGFDYRPFVLNWCMSLKYIDGFVVDPIESLKA 240

Mouse   343 EEIRQRLKEEQDQDLDPDQDMEPYLPPV 370
            |.:..:.:..|.: :...|.:..||..|
  Fly   241 EWLYSQGRGRQFR-VGEQQGLAKYLSSV 267

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lrrc23XP_006505721.1 leucine-rich repeat 100..119 CDD:275380 5/18 (28%)
internalin_A 105..>311 CDD:380193 57/217 (26%)
leucine-rich repeat 120..141 CDD:275380 1/20 (5%)
leucine-rich repeat 142..162 CDD:275380 3/19 (16%)
leucine-rich repeat 163..183 CDD:275380 7/22 (32%)
leucine-rich repeat 184..207 CDD:275380 6/22 (27%)
leucine-rich repeat 208..228 CDD:275380 7/20 (35%)
leucine-rich repeat 229..250 CDD:275380 7/20 (35%)
leucine-rich repeat 251..273 CDD:275380 5/23 (22%)
leucine-rich repeat 274..298 CDD:275380 10/23 (43%)
Cep97NP_608811.2 leucine-rich repeat 11..31 CDD:275380 1/1 (100%)
leucine-rich repeat 32..53 CDD:275380 5/20 (25%)
LRR_RI <49..189 CDD:238064 49/187 (26%)
LRR_4 76..115 CDD:289563 13/40 (33%)
leucine-rich repeat 76..97 CDD:275380 6/20 (30%)
LRR_8 97..152 CDD:290566 21/58 (36%)
LRR_4 97..137 CDD:289563 13/43 (30%)
leucine-rich repeat 98..119 CDD:275380 7/24 (29%)
leucine-rich repeat 120..141 CDD:275380 7/20 (35%)
LRR_8 140..200 CDD:290566 25/82 (30%)
leucine-rich repeat 142..165 CDD:275380 12/45 (27%)
leucine-rich repeat 166..190 CDD:275380 10/23 (43%)
IQ 581..599 CDD:197470
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
10.910

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