DRSC/TRiP Functional Genomics Resources

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Protein Alignment Lrpap1 and CG8507

DIOPT Version :9

Sequence 1:NP_038615.2 Gene:Lrpap1 / 16976 MGIID:96829 Length:360 Species:Mus musculus
Sequence 2:NP_649950.1 Gene:CG8507 / 41205 FlyBaseID:FBgn0037756 Length:379 Species:Drosophila melanogaster


Alignment Length:368 Identity:109/368 - (29%)
Similarity:183/368 - (49%) Gaps:63/368 - (17%)


- Green bases have known domain annotations that are detailed below.


Mouse    37 KYSREKNEPE-MAAKRESGE--------EFRMEKLNQLWEKAKRLHLSPVRLAELHSDLKIQERD 92
            |||:|.|:|. ...|:|..:        .|||.|||.:|.||:. .|:..:|..|:.:|||.:::
  Fly    31 KYSKEANDPHFQQVKQEKYDPDFKSIQRPFRMAKLNLVWAKAQN-RLTEPKLKSLYMELKIHDKE 94

Mouse    93 ELNWKKLKVEGLDKDGEKEAKLIHNLNVILARYGL----DGRKDAQMVHSNALNEDTQDE----- 148
            |:.||:|..:..||||.|..:|...|..|::.|.|    |..:|.:.:.......|.::.     
  Fly    95 EIAWKQLNSQHKDKDGLKADELRRKLIGIMSSYDLLEHFDDTQDTEKLKPYKKFHDAEERHRNKS 159

Mouse   149 -LGDPRLEKLWHKAKTSGKFSSEELDKLWREFLHYKEKIQEYNVLLDTLSRAE-EGYENLLSPSD 211
             ..|.:|.:||.||:.|| |::|||..|.:||.|:::|:..|..||:.:...: :.:||.::..|
  Fly   160 LFKDKKLNRLWEKAEISG-FTAEELKSLKQEFDHHQDKVDVYYSLLENIGTVDTDKHENAINTED 223

Mouse   212 M-------------------AHIKS-----DTLISKHSELKDRLRSINQGLDRLRKVSHQGYGST 252
            :                   .::||     :||...|:.:||.       .|||.::...|..| 
  Fly   224 LDTYNLISNDVNENDIKTHAQNVKSFENDLNTLRGHHTGIKDH-------YDRLERLVSSGPHS- 280

Mouse   253 TEFEEPRVIDLWDLAQSANFTEKELESFREELKHFEAKIEKHNHYQKQLEISHQKLKHVESIGDP 317
            .:|.||:|..||.:||::|||.|||||.:.||.|||:::.|..|...:..:..:|.|       .
  Fly   281 QDFIEPKVQGLWRVAQASNFTVKELESIKTELHHFESRLLKLRHLHAEHALQKEKYK-------G 338

Mouse   318 EHISRNKEKYVLLEEKTKELGYKVKKHLQDLSSRVSRARHNEL 360
            |.:.....::..:|::.|:...||:|..:::...:  .:|.||
  Fly   339 EKVKDKSSRFEEMEDQLKKQTRKVEKLQENIEKTI--FKHTEL 379

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Lrpap1NP_038615.2 Alpha-2-MRAP_N 31..134 CDD:283943 39/109 (36%)
3-helical coiled coil 61..70 CDD:269813 5/8 (63%)
3-helical coiled coil 78..99 CDD:269813 8/20 (40%)
3-helical coiled coil 110..123 CDD:269813 4/12 (33%)
Alpha-2-MRAP_C 149..360 CDD:283944 67/235 (29%)
RAP_D2 149..246 CDD:269814 33/121 (27%)
3-helical coiled coil 153..162 CDD:269814 4/8 (50%)
3-helical coiled coil 170..198 CDD:269814 11/27 (41%)
3-helical coiled coil 223..246 CDD:269814 6/22 (27%)
RAP_D3 255..360 CDD:269815 32/104 (31%)
3-helical coiled coil 262..269 CDD:269815 3/6 (50%)
3-helical coiled coil 276..309 CDD:269815 12/32 (38%)
3-helical coiled coil 324..353 CDD:269815 5/28 (18%)
CG8507NP_649950.1 Alpha-2-MRAP_N 15..140 CDD:399416 39/109 (36%)
Alpha-2-MRAP_C 161..379 CDD:399417 67/235 (29%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C167849507
Domainoid 1 1.000 95 1.000 Domainoid score I7412
eggNOG 1 0.900 - - E1_KOG3956
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H37612
Inparanoid 1 1.050 143 1.000 Inparanoid score I4439
Isobase 1 0.950 - 0 Normalized mean entropy S5708
OMA 1 1.010 - - QHG49282
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 1 1.000 - - FOG0007150
OrthoInspector 1 1.000 - - oto93144
orthoMCL 1 0.900 - - OOG6_107561
Panther 1 1.100 - - LDO PTHR16560
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R6462
SonicParanoid 1 1.000 - - X6028
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 1 0.960 - -
1615.740

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