DRSC/TRiP Functional Genomics Resources

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Protein Alignment QSOX2 and Qsox2

DIOPT Version :10

Sequence 1:NP_859052.3 Gene:QSOX2 / 169714 HGNCID:30249 Length:698 Species:Homo sapiens
Sequence 2:NP_650998.1 Gene:Qsox2 / 42583 FlyBaseID:FBgn0038919 Length:552 Species:Drosophila melanogaster


Alignment Length:563 Identity:169/563 - (30%)
Similarity:273/563 - (48%) Gaps:65/563 - (11%)


- Green bases have known domain annotations that are detailed below.


Human    36 LLVLLAAAAVG----PGAGGAARLYRAGEDAVWVLDSGSVRGATANSSAAWLVQFYSSWCGHCIG 96
            ||::..|..:|    ..:...|.|| :..|.|.:||..|:|.| .|...:.||||.:|:||.|..
  Fly    12 LLLISPADVLGRLNARKSANEASLY-SDTDNVIMLDIESLRPA-LNLKNSKLVQFLNSFCGDCHR 74

Human    97 YAPTWRALAGDVRDWASAIRVAALDCMEEKNQAVCHDYDIHFYPTFRYFKAFTK--EFTTGENFK 159
            :||.::.|:.|:..|...:|:.|:||.:|:|..:|.:::|...|:.|:|....:  :...|....
  Fly    75 FAPVFKTLSRDLYKWRRILRIYAVDCAQERNAQLCREFNIRQTPSLRFFGPDMRKNDDVLGAVIP 139

Human   160 GPDRELRTVRQTMIDFLQNHTEGSRPPACPRLDPIQPSDVLSLLDNRGS---HYVAIVFESNSSY 221
            |.|.|.  :..|:.:.:..:..|   |..|...|::.:|.....|..|.   .:||:|.:..:|.
  Fly   140 GQDPEF--ISSTLAELVSQNDYG---PGQPNFRPLKATDYEIFQDQDGETPIQFVALVLQPKNSK 199

Human   222 LGREVILDLIPYESIVVTRALDGDKAFLE--------KLGVSSVPSCYLIYPNGSHGLINVVKPL 278
            :||:.:|:|:|::.:.| |.::..:.|.|        ||.:..           .:|....:.|.
  Fly   200 IGRDTLLELLPFKELSV-RIIEDSQIFNEFGLGPDDQKLAIVD-----------RNGTAQYLTPS 252

Human   279 RAFFSSYLKSLPDVRKK-------SLPLPEKPH-----KEENSEIVVWREFDKSKLYTVDLESGL 331
            .....:|..::.|..|.       .||:...|:     ..:|..|:........::|..|||..:
  Fly   253 SDSSEAYASTIGDFLKNRNIQPDPPLPIAVAPNFTEFLDHQNQAILTKVLTPPLQVYRADLEQAI 317

Human   332 HYLLRVELAAHKSLAGAELKTLKDFVTVLAKLFPGRPPVKKLLEMLQEWLAS-LPLDRIPYNAVL 395
            ..||.:||.....|.|..|..||:.:.:...|.|.....|.||..|...|:| ..:....:..::
  Fly   318 DKLLHIELRKWVLLEGNSLNALKNIIKIFRYLNPLNKDGKLLLTDLDNSLSSKQSIKGADFGDLV 382

Human   396 DLVNNKMRISGIFLTNHIKWVGCQGSRSELRGYPCSLWKLFHTLTVEASTHPDALVGTGFEDDPQ 460
            |.:.|..|   :|...  ::|||.|||..||.:.||:|.|||.|||||:..|:..       :..
  Fly   383 DSLENGRR---VFKAR--RYVGCIGSRPLLRSFTCSMWTLFHHLTVEAAKPPNYF-------EAG 435

Human   461 AVLQTMRRYVHTFFGCKECGEHFEEMA-KESMDSVKTPDQAILWLWKKHNMVNGRLAGHLSEDPR 524
            ::|:|...:...||||.:|.|||::|| :.::.||||.|:.|||||..||.||.|:||..:|||:
  Fly   436 SILKTFHGFAKYFFGCTDCSEHFQQMAIRRNLTSVKTHDEEILWLWAAHNEVNARIAGDSTEDPK 500

Human   525 FPKLQWPTPDLCPACHEEIKGLASWDEGHVLTFLKQHYGRDNL 567
            |||:|:|:.:.||.|....   :.|....||.:|||.|..:|:
  Fly   501 FPKIQFPSAENCPTCRSND---SEWRTDEVLKYLKQLYDINNV 540

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
QSOX2NP_859052.3 PDI_a_QSOX 61..174 CDD:239290 37/114 (32%)
QSOX_Trx1 185..292 CDD:465653 24/117 (21%)
FAD_SOX 318..421 CDD:465728 28/103 (27%)
Evr1_Alr 430..531 CDD:461423 48/101 (48%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 570..624
Qsox2NP_650998.1 PDI_a_QSOX 40..152 CDD:239290 37/114 (32%)
FAD_SOX 307..403 CDD:465728 28/100 (28%)
Evr1_Alr 412..507 CDD:461423 48/101 (48%)
Blue background indicates that the domain is not in the aligned region.

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