DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Lipg and CG6295

DIOPT Version :9

Sequence 1:	NP_034850.3	Gene:	Lipg / 16891	MGIID:	1341803	Length:	500	Species:	Mus musculus
Sequence 2:	NP_651521.1	Gene:	CG6295 / 43247	FlyBaseID:	FBgn0039471	Length:	338	Species:	Drosophila melanogaster

Alignment Length:	313	Identity:	94/313 - (30%)
Similarity:	149/313 - (47%)	Gaps:	59/313 - (18%)

- Green bases have known domain annotations that are detailed below.

Mouse    49 VAFNIRTSKD---PEQ-EGCNLSLGDSKLLENCGFNMTAKTFFIIHGWTMS-------GMFESWL 102
            |.|.:.|:.:   |:: :..:.|:..|.      ||....|.|.||||:.|       |:.::|
  Fly    64 VTFYLYTNSNRNSPQEIKATSASISGSH------FNPNHPTRFTIHGWSSSKDEFINYGVRDAW- 121

Mouse   103 HKLVSALQMREKDANVVVVDWLPLAHQLYTDAVNNTRVVGQRVAGMLDWLQEKEEFSLGNVHLIG 167
                    ....|.|::.|||.......|..:|.....||::||.::::::.....:|.|..:||
  Fly   122 --------FTHGDMNMIAVDWGRARSVDYASSVLAVPGVGEQVATLINFMRSNHGLNLDNTMVIG 178

Mouse   168 YSLGAHVAGYAGNFVK-GTVGRITGLDPAGPMFEGVDINRRLSPDDADFVDVLHTYTLSFGLSIG 231
            :||||||:||||..|| |.:..|.|||||.|:|.....|:|||..||.:|:.:.|.    |.::|
  Fly   179 HSLGAHVSGYAGKNVKNGQLHTIIGLDPALPLFSYDSPNKRLSSTDAYYVESIQTN----GGTLG 239

Mouse   232 IRMPVGHIDIYPNGGDFQPGCGFNDVIGSFAYGTISEMVKCEHERAVHLFVDSLVNQDKPSFAFQ 296
            ...|:|....|||||..|||||. |:.||           |.|.|:|..:.:|:...:.|:  .:
  Fly   240 FLKPIGKGAFYPNGGKSQPGCGV-DLTGS-----------CAHSRSVIYYAESVTENNFPT--MR 290

Mouse   297 CTDSSRFKRGICLSCRKNRCNNIGYNAKKMRKKRNSKM-----YLKTRAGMPF 344
            |.|   ::..:...|..:      |::.:|....|:.|     |:..|:..|:
  Fly   291 CGD---YEEAVAKECGSS------YSSVRMGATTNAYMVAGDYYVPVRSDAPY 334

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lipg	NP_034850.3	Pancreat_lipase_like	49..340	CDD:238363	92/307 (30%)
		lipo_lipase	51..485	CDD:132274	93/311 (30%)
		Heparin-binding. /evidence=ECO:0000250	325..337		4/16 (25%)
		PLAT_LPL	347..483	CDD:238856
CG6295	NP_651521.1	Pancreat_lipase_like	64..330	CDD:238363	92/307 (30%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167835328
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11610
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.940