DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BHLHA15 and tx

DIOPT Version :9

Sequence 1:	NP_803238.1	Gene:	BHLHA15 / 168620	HGNCID:	22265	Length:	189	Species:	Homo sapiens
Sequence 2:	NP_001287543.1	Gene:	tx / 43190	FlyBaseID:	FBgn0263118	Length:	384	Species:	Drosophila melanogaster

Alignment Length:	158	Identity:	45/158 - (28%)
Similarity:	63/158 - (39%)	Gaps:	50/158 - (31%)

- Green bases have known domain annotations that are detailed below.

Human     3 TKNRPPRRRAPVQDTEATPGE------------GTPDGSLPN---------PGPEPA-KGLRSRP 45
            |.::..|:|    .|.:..||            ...||...|         |..||| |..::.|
  Fly    21 TDSKDSRKR----KTASARGEKYSLRQKRQKRGSNEDGESANLADFQLELDPIAEPASKSRKNAP 81

Human    46 ARAAARAPGEGRRRRPGPSGPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPH------ 104
            .::..:||                 ..|..||..:|.|||.||.::|.||:.||..:|.
  Fly    82 TKSKTKAP-----------------PLSKYRRKTANARERTRMREINTAFETLRHCVPEAIKGED 129

Human   105 -VRADKKLSKIETLTLAKNYIKSLTATI 131
             ...::||:||.||.||..||..||.:|
  Fly   130 AANTNEKLTKITTLRLAMKYITMLTDSI 157

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BHLHA15	NP_803238.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..85		22/103 (21%)
		HLH	81..127	CDD:197674	22/52 (42%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..189
tx	NP_001287543.1	HLH	95..154	CDD:278439	24/58 (41%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0005380
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19290
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	3	3.010