DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment BHLHA15 and ac

DIOPT Version :9

Sequence 1:	NP_803238.1	Gene:	BHLHA15 / 168620	HGNCID:	22265	Length:	189	Species:	Homo sapiens
Sequence 2:	NP_476824.1	Gene:	ac / 30981	FlyBaseID:	FBgn0000022	Length:	201	Species:	Drosophila melanogaster

Alignment Length:	112	Identity:	38/112 - (33%)
Similarity:	51/112 - (45%)	Gaps:	31/112 - (27%)

- Green bases have known domain annotations that are detailed below.

Human    64 SGPGGRRDSSIQRRLESNERERQRMHKLNNAFQALREVIPHV--------------RADKKLSKI 114
            :||      |:.||   |.|||.|:.::||.|..||:.||..              .|:|||||:
  Fly    22 NGP------SVIRR---NARERNRVKQVNNGFSQLRQHIPAAVIADLSNGRRGIGPGANKKLSKV 77

Human   115 ETLTLAKNYIKSLTATILTMSSSRLPGLEGPGPKLYQ---HYQQQQQ 158
            .||.:|..||:.|...:......:...|.     |.|   |:|||||
  Fly    78 STLKMAVEYIRRLQKVLHENDQQKQKQLH-----LQQQHLHFQQQQQ 119

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
BHLHA15	NP_803238.1	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	1..85		7/20 (35%)
		HLH	81..127	CDD:197674	23/59 (39%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	167..189
ac	NP_476824.1	HLH	30..96	CDD:197674	24/65 (37%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910