DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment RNF133 and Rnf133

DIOPT Version :9

Sequence 1:NP_631914.1 Gene:RNF133 / 168433 HGNCID:21154 Length:376 Species:Homo sapiens
Sequence 2:NP_937894.1 Gene:Rnf133 / 386611 MGIID:2677436 Length:339 Species:Mus musculus


Alignment Length:376 Identity:246/376 - (65%)
Similarity:277/376 - (73%) Gaps:44/376 - (11%)


- Green bases have known domain annotations that are detailed below.


Human     1 MHLLKVGTWRNNTASSWLMKFSVLWLVSQNCCRASVVWMAYMNISFHVGNHVLSELGETGVFGRS 65
            |:.|:..||:|...|.||::||.:|||||.||.||.||.|||||||||||.:|||||||||||||
Mouse     1 MNPLQTSTWQNQAPSFWLLRFSFIWLVSQKCCTASAVWTAYMNISFHVGNRMLSELGETGVFGRS 65

Human    66 STLKRVAGVIVPPEGKIQNACNPNTIFSRSKYSETWLALIERGGCTFTQKIKVATEKGASGVIIY 130
            |.|||||||:|||||||||||:|||.|...:..|.|:||||||||.||||||||:|.||.|||||
Mouse    66 SILKRVAGVVVPPEGKIQNACDPNTTFILPRNKEPWIALIERGGCAFTQKIKVASEHGARGVIIY 130

Human   131 NVPGTGNQVFPMFHQAFEDVVVVMIGNLKGTEIFHLIKKGVLITAVVEVGRKHIIWMNHYLVSFV 195
            |.||||||||||.||||||:|||||||:|                                    
Mouse   131 NFPGTGNQVFPMSHQAFEDIVVVMIGNIK------------------------------------ 159

Human   196 IVTTATLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGDSCVICF 260
                   |||.||||.||.:|||:||||:|||.:|:..|||||:||:||||||:|||.|||||||
Mouse   160 -------AYFTFYHIRRLWVARIENRRWKRLTRELKKAFGQLQVRVLKEGDEEVNPNADSCVICF 217

Human   261 ERYKPNDIVRILTCKHFFHKNCIDPWILPHGTCPICKCDILKVLGIQVVVENGTEPLQVLMSNEL 325
            |.||||:|||||||||||||||||||||.|||||:|||||||.||||:.:|:||:.|||||||||
Mouse   218 EAYKPNEIVRILTCKHFFHKNCIDPWILAHGTCPMCKCDILKALGIQMDIEDGTDSLQVLMSNEL 282

Human   326 PETLSPSEEETNNEVSPAGTSDKVIHVEENPTSQ-NNDIQPHSVVEDVHPS 375
            |.||||.|||||.|:.||.||.||.||:|:|||. |...||....|..|||
Mouse   283 PGTLSPVEEETNYELPPARTSSKVTHVQEHPTSSANAGSQPPEAEETSHPS 333

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
RNF133NP_631914.1 PA_GRAIL_like 43..177 CDD:239037 95/133 (71%)
RING_Ubox 254..302 CDD:327409 43/47 (91%)
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite 327..376 29/50 (58%)
Rnf133NP_937894.1 PA_GRAIL_like 43..159 CDD:239037 94/115 (82%)
zf-RING_2 211..254 CDD:290367 38/42 (90%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 1 0.930 - - C83953519
Domainoid 1 1.000 150 1.000 Domainoid score I34097
eggNOG 1 0.900 - - E1_KOG4628
HGNC 1 1.500 - -
Hieranoid 1 1.000 - -
Homologene 1 1.000 - - H44549
Inparanoid 1 1.050 587 1.000 Inparanoid score I10778
Isobase 00.000 Not matched by this tool.
NCBI 1 1.000 - -
OMA 1 1.010 - - QHG46333
OrthoDB 1 1.010 - - D1487241at2759
OrthoFinder 1 1.000 - - FOG0016015
OrthoInspector 1 1.000 - - oto120034
orthoMCL 1 0.900 - - OOG6_138581
Panther 1 1.100 - - LDO PTHR22765
Phylome 1 0.910 - -
RoundUp 1 1.030 - avgDist Average_Evolutionary_Distance R13345
SonicParanoid 1 1.000 - - X295
SwiftOrtho 1 1.000 - -
TreeFam 1 0.960 - -
1919.300

Return to query results.
Submit another query.