Protein Alignment RNF133 and rnf128a

DIOPT Version :9

• Sequence 1: NP_631914.1
• Gene: RNF133 / 168433
• HGNCID: 21154
• Length: 376
• Species: Homo sapiens
• Sequence 2: NP_997780.1
• Gene: rnf128a / 322325
• ZFINID: ZDB-GENE-030131-1044
• Length: 389
• Species: Danio rerio
• Alignment Length: 395
• Identity: 154/395 - (38%)
• Similarity: 225/395 - (56%)
• Gaps: 40/395 - (10%)

Human     6 VGTWRNNTASSWLMKFSVLWLVSQNCCRASVVWMAYMNISF--HVGNHVLSELGETGVFGRSSTL 68
            :|...:....|||:..|||.:.|.....||.:..||:|||:  ...|.......|.|::|:.|..
Zfish     1 MGPLASRDVFSWLLLASVLQVSSVRLAEASYLCTAYLNISYTNPENNRSTWFQEEMGLYGQDSPK 65

Human    69 KRVAGVIV---PPEGKIQNACNPNTIFSRSKYSETWLALIERG-GCTFTQKIKVATEKGASGVII 129
            ..|.|.:.   |..|     |:.:|.:.|...|:.|:|||:|| |||||:||.:|...||:..||
Zfish    66 AYVKGNVYLASPTYG-----CDDDTFYGRPNGSKGWIALIQRGNGCTFTEKINIAAMNGAAAAII 125

Human   130 YNVPGTGNQVFPMFHQAFEDVVVVMIGNLKGTEIFHLIKKGVLITAVVEVGRKHIIWMNHYLV-- 192
            :|..|:.|:|..|.|.. ..:|.:||||.:|.|:..|:.:||.:...:|||::|..||:||.|
Zfish   126 FNDFGSENRVIQMSHPG-TTIVAIMIGNYRGMELVQLLDQGVPVAIAIEVGKQHGPWMSHYSVFF 189

Human   193 ---SFVIVTTATLAYFIFYHIHRLCLARIQNRRWQRLTTDLQNTFGQLQLRVVKEGDEEINPNGD 254
               ||.|||.||:.|||||...||...|.|||..::|..:.:...||||:|.:::||:||.|:.|
Zfish   190 VSISFFIVTAATVGYFIFYSARRLNSLRQQNRSQKKLKAEAKKAIGQLQVRTLRQGDQEIGPDAD 254

Human   255 SCVICFERYKPNDIVRILTCKHFFHKNCIDPWILPHGTCPICKCDILKVLGIQVVVENGTEPLQV 319
            :|.:|.:.||..|::.||||.|||||:||:||:|.|.|||:|||||||.||:::.||   |..|:
Zfish   255 ACAVCIDSYKAGDVLSILTCNHFFHKSCIEPWLLEHRTCPMCKCDILKALGVELDVE---EQPQI 316

Human   320 LMSNELPETLSPSEE-------ETNNEVSPAGTSDKVIHVEEN---PTSQNNDIQ--PH----SV 368
            .:.:..|  .|.||:       .|::|.:.:|.:.  :|..|:   |...:|.:|  ||    :.
Zfish   317 SVPDFRP--FSTSEDLHSETASHTHSETASSGYAS--MHGNEHLAPPEGTHNGVQEEPHYDNLAF 377

Human   369 VEDVH 373
            ..|||
Zfish   378 ESDVH 382

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RNF133	NP_631914.1	PA_GRAIL_like	43..177	CDD:239037	50/139 (36%)
		RING_Ubox	254..302	CDD:327409	29/47 (62%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	327..376		16/63 (25%)
rnf128a	NP_997780.1	PA_GRAIL_like	38..172	CDD:239037	50/139 (36%)
		zf-RING_2	256..297	CDD:290367	23/40 (58%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I30986
eggNOG	1	0.900	-	-		E1_KOG4628
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	7	6.880