Protein Alignment Lamc2 and NetA

DIOPT Version :10

• Sequence 1: NP_032511.3
• Gene: Lamc2 / 16782
• MGIID: 99913
• Length: 1193
• Species: Mus musculus
• Sequence 2: NP_511154.3
• Gene: NetA / 32398
• FlyBaseID: FBgn0015773
• Length: 726
• Species: Drosophila melanogaster
• Alignment Length: 410
• Identity: 106/410 - (25%)
• Similarity: 156/410 - (38%)
• Gaps: 100/410 - (24%)

Mouse    28 CDCNGKSRQCVFDQELHRQTGSGFRCLNCNDNTAGVHCERCREGFYRHRDR----------DRCL 82
            |.|||.:.:|..|       .||.....|:.||||..||||:.   .|.||          :.|.
  Fly   313 CKCNGHASKCSTD-------ASGQLNCECSHNTAGRDCERCKP---FHFDRPWARATAKEANECK 367

Mouse    83 PCNCHSKG----------SLSAGCDNSGQCR-CKPGVTGQRCDRCQPGFHMLTDAGCTRDQGQLD 136
            .|||:...          .||.|. :.|.|: |:...||:.|.:|:.||:  .||.......::.
  Fly   368 ECNCNKHARQCRFNMEIFRLSQGV-SGGVCQNCRHSTTGRNCHQCKEGFY--RDATKPLTHRKVC 429

Mouse   137 SKCDCDPAGISGP-CD--SGRCVCKPAVTGERCDRCRPGYYHLDRANPEGCTQCFCYGHSASCHA 198
            ..|||.|.|.||. |:  ||:|.||..|||..|:||..||..             ...|.|.|..
  Fly   430 KACDCHPIGSSGKICNSTSGQCPCKDGVTGLTCNRCARGYQQ-------------SRSHIAPCIK 481

Mouse   199 SADFSVHKI-TSTFSQDVDGWKAV-----QRNGAPAKLHWSQRHR-----------------DVF 240
            .....::.: |...:.:.|..::.     .||||......||.:|                 ::.
  Fly   482 QPPRMINMLDTQNTAPEPDEPESSPGSGGDRNGAAGMAAQSQYYRTEGGRECGKCRVSTKRLNLN 546

Mouse   241 SSARRSDPVYFVAPAKFLGNQQVSYGQSLSFDYRVDRGGRQPSAYDVILEGAGLQIRAPLMAPGK 305
            ...:|.    :...||.:|....|...|    ..|.|....|...|..::    |::     ||
  Fly   547 KFCKRD----YAIMAKVIGRDTSSEAVS----REVQRRAMDPDVADYEMD----QVQ-----PG- 593

Mouse   306 TLPCGITKTYTFRLNEHPSSHWSPQLSYFEYRRLLRNLTALLIRATYGEYSTGYIDNVTLVSARP 370
            :....||..|.|:..::|:.:.:|:.|  |..|....:.|:..|:..|| |:| ..||..:....
  Fly   594 SARSPITGVYEFQAADYPNPNPNPRGS--EMERFDLQIQAVFKRSRPGE-SSG-AGNVYGMPNTT 654

Mouse   371 VSGAPAPWV-----ERCVCP 385
            :...|..|:     ..|.||
  Fly   655 LKRGPMTWIIPTKDLECRCP 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Lamc2	NP_032511.3	Laminin_EGF	28..86	CDD:395007	22/67 (33%)
		EGF_Lam	83..127	CDD:238012	16/54 (30%)
		Laminin_EGF	139..184	CDD:395007	21/47 (45%)
		Laminin_B	250..380	CDD:459652	31/134 (23%)
		EGF_Lam	461..509	CDD:238012
		Laminin_EGF	517..564	CDD:395007
		EGF_Lam	572..>604	CDD:238012
		Cell attachment site. /evidence=ECO:0000255	586..588
		SMC_prok_B	<614..1181	CDD:274008
NetA	NP_511154.3	LamNT	44..280	CDD:214532
		EGF_Lam	312..357	CDD:238012	20/53 (38%)
		EGF_Lam	369..426	CDD:238012	17/59 (29%)
		EGF_Lam	431..479	CDD:238012	23/60 (38%)
		NTR_netrin-1_like	545..723	CDD:239634	35/152 (23%)