DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Lama5 and LanA

DIOPT Version :9

Sequence 1:	XP_006500638.1	Gene:	Lama5 / 16776	MGIID:	105382	Length:	3745	Species:	Mus musculus
Sequence 2:	NP_476617.1	Gene:	LanA / 38723	FlyBaseID:	FBgn0002526	Length:	3712	Species:	Drosophila melanogaster

Alignment Length:	3984	Identity:	1253/3984 - (31%)
Similarity:	1864/3984 - (46%)	Gaps:	613/3984 - (15%)

- Green bases have known domain annotations that are detailed below.

Mouse    50 LHPPYFNLAEGARITASATCGEEAPTRSVSRPTEDLYCKLVGGPVAGGDPN-QTIQGQYCDICTA 113
            |.|||||||.|.:|.|:||||::.       ...:|||||||........: ..||||.||.|..
  Fly    24 LTPPYFNLATGRKIYATATCGQDT-------DGPELYCKLVGANTEHDHIDYSVIQGQVCDYCDP 81

Mouse   114 ANSNKAHPVSNAIDGTERWWQSPPLSRGLEYNEVNVTLDLGQVFHVAYVLIKFANSPRPDLWVLE 178
            ....:.||..|||||||.||||||||||:::||||:|::..|.|||||:.|:..|||||.||.||
  Fly    82 TVPERNHPPENAIDGTEAWWQSPPLSRGMKFNEVNLTINFEQEFHVAYLFIRMGNSPRPGLWTLE 146

Mouse   179 RSTDFGHTYQPWQFFASSKRDCLERFGPRTLERITQDDDVICTTEYSRIVPLENGEIVVSLVNGR 243
            :|||:|.|:.|||.|:.:..||...||..|.:.||:|||||||||||:|||||||||.|.|:|.|
  Fly   147 KSTDYGKTWTPWQHFSDTPADCETYFGKDTYKPITRDDDVICTTEYSKIVPLENGEIPVMLLNER 211

Mouse   244 PGALNFSYSPLLRDFTKATNIRLRFLRTNTLLGHLMGKALRDPTVTRRYYYSIKDISIGGRCVCH 308
            |.:.|:..|.:|:::|:|||:|:|.|||..||||||..|.:||||||||:||||||||||||:|:
  Fly   212 PSSTNYFNSTVLQEWTRATNVRIRLLRTKNLLGHLMSVARQDPTVTRRYFYSIKDISIGGRCMCN 276

Mouse   309 GHADVCDAKDPLDPFR-LQCACQHNTCGGSCDRCCPGFNQQPWKPATTDSANECQSCNCHGHAYD 372
            ||||.||.|||..|.| |.|.|||:|||..|:.|||||.|:.|:..|......|:.||||||:.:
  Fly   277 GHADTCDVKDPKSPVRILACRCQHHTCGIQCNECCPGFEQKKWRQNTNARPFNCEPCNCHGHSNE 341

Mouse   373 CYYDPEVDRRNASQNQDNVYQGGGVCLDCQHHTTGINCERCLPGFFRAPDQPLDSPHVCRPCDCE 437
            |.||.||:|:..|.:....|.|||||.:|||:|.||||.:|.|.::|...:..:...||.||.|:
  Fly   342 CKYDEEVNRKGLSLDIHGHYDGGGVCQNCQHNTVGINCNKCKPKYYRPKGKHWNETDVCSPCQCD 406

Mouse   438 SDFTDGTCEDLTGRCYCRPNFTGELCAACAEGYTDFPHCYPLPSFPHNDTREQVLPAGQIVNCDC 502
            ..|:.|.||:.||.|.||..|....|.:||.||..:|:|           ||          |:|
  Fly   407 YFFSTGHCEEETGNCECRAAFQPPSCDSCAYGYYGYPNC-----------RE----------CEC 450

Mouse   503 NAAGTQGNACRKDPRLGRCVCKPNFRGAHCELCAPGFHG-PSCHPCQCSSPGVANSLCDPESGQC 566
            |..||.|..|..:.. .:|.||.||.||:|:.||.|::| |.|..|:|:..|...:.|:..:|:|
  Fly   451 NLNGTNGYHCEAESG-QQCPCKINFAGAYCKQCAEGYYGFPECKACECNKIGSITNDCNVTTGEC 514

Mouse   567 MCRTGFEGDRCDHCALGYFHFPLCQLCGCSPAGTLPEGCD-EAGRCQCRPGFDGPHCDRCLPGYH 630
            .|.|.|.||.|:.|..|||::|.|..|.|...||..|.|: ::|:|.||.||.||.||:||||::
  Fly   515 KCLTNFGGDNCERCKHGYFNYPTCSYCDCDNQGTESEICNKQSGQCICREGFGGPRCDQCLPGFY 579

Mouse   631 GYPDCHACACDPRGALDQQCGVGGLCHCRPGYTGATCQECSPGFYGFPSCIPCHCSADGSLHTTC 695
            .||||..|.|...|:....|...|.|:|...:.|..|..|:.|:|.:|.|:||||.:.||...:|
  Fly   580 NYPDCKPCNCSSTGSSAITCDNTGKCNCLNNFAGKQCTLCTAGYYSYPDCLPCHCDSHGSQGVSC 644

Mouse   696 DPTTGQCRCRPRVTGLHCDMCVPGAYNFPYCEAGSCHPAGLA---PANPALPETQAPCMCRAHVE 757
            : :.|||.|:|...|..||.|..|.||||.||..:|.|||:.   ....::|..:. |.|:..|.
  Fly   645 N-SDGQCLCQPNFDGRQCDSCKEGFYNFPSCEDCNCDPAGVIDKFAGCGSVPVGEL-CKCKERVT 707

Mouse   758 GPSCDRCKPGYWGLSASNPEGCTRCSCDPRGTLGGVTECQG-NGQCFCKAHVCGKTCAACKDGFF 821
            |..|:.|||.||.|:.||.|||..|.|...||:..:..|.. :|||.||.|..|:.|..|:||.|
  Fly   708 GRICNECKPLYWNLNISNTEGCEICDCWTDGTISALDTCTSKSGQCPCKPHTQGRRCQECRDGTF 772

Mouse   822 GLDYADYFGCRSCRCDVGGALGQGCEPKTGACRCRPNTQGPTCSEPAKDHYLPDLHHMRLELEEA 886
            .||.|..|||:.|.|||||:....|:..:|.|:|.|...|..|::|...|:.|.||..:.|.|:.
  Fly   773 DLDSASLFGCKDCSCDVGGSWQSVCDKISGQCKCHPRITGLACTQPLTTHFFPTLHQFQYEYEDG 837

Mouse   887 ATPEGHAVRFGFNPLEFENFSWRGYAHMMAIQPRIVARLNVTSPDLFRLVFRYVNRGSTSVNGQI 951
            :.|.|..||:.::...|..||.:||....|||..:...:||....|:|:|.||||..:.:|...|
  Fly   838 SLPSGTQVRYDYDEAAFPGFSSKGYVVFNAIQNDVRNEVNVFKSSLYRIVLRYVNPNAENVTATI 902

Mouse   952 SVREEGKLSSCTNCTEQSQPVAFPPSTEPAFVTV--PQRGFGEPFVLNPGIWALLVEA-EGVLLD 1013
            ||..:..|.     .:|...|...|::||.||||  |........||:||.:....:| :.|:||
  Fly   903 SVTSDNPLE-----VDQHVKVLLQPTSEPQFVTVAGPLGVKPSAIVLDPGRYVFTTKANKNVMLD 962

Mouse  1014 YVVLLPSTYYEAALLQHRVTEACTYRPSALHSTENCLVYAHLPLDGFPSAAGTEALCRHDNSLPR 1078
            |.||||:.||||.:|...::..|     .|.:.|.|..|.:..::.|..||....:  .:||.|.
  Fly   963 YFVLLPAAYYEAGILTRHISNPC-----ELGNMELCRHYKYASVEVFSPAATPFVI--GENSKPT 1020

Mouse  1079 PCPTEQLSPSH----------PPLATCFGSDVDIQLEMAVPQPGQYVLVVEYVGE----DSHQEM 1129
            ........|.|          |.|:   ||..::...:.||:.|:|:.|::|:.:    ||:.
  Fly  1021 NPVETYTDPEHLQIVSHVGDIPVLS---GSQNELHYIVDVPRSGRYIFVIDYISDRNFPDSYY-- 1080

Mouse  1130 GVAVHTPQRAPQQGVLNLHPCPYSSLCRSPARDTQHHLAIFYLDSE--ASIRLTA---EQAHFFL 1189
             :.:........:..:.|:||.||::||:...:.....: ||::.|  ..:.::|   :.:.|.:
  Fly  1081 -INLKLKDNPDSETSVLLYPCLYSTICRTSVNEDGMEKS-FYINKEDLQPVIISADIEDGSRFPI 1143

Mouse  1190 HSVTLVPVEEFSTEFVEPRVFCVSSHGTFNPSSAACLASRFPKPPQPIILKDCQVLPLPPDLPLT 1254
            .|||.:||:::|.:::.|...||.       ....|...:|...|      |.:.:....|
  Fly  1144 ISVTAIPVDQWSIDYINPSPVCVI-------HDQQCATPKFRSVP------DSKKIEFETD---- 1191

Mouse  1255 QSQELSPGAPPEGPQPRPPTAVDPNAEPTLLRH----PQGTVVFTTQV----PTLGRYAFLLHGY 1311
            ....::...||.       .::|   |...|.|    .:.|:|..::|    |.|  :..|:..|
  Fly  1192 HEDRIATNKPPY-------ASLD---ERVKLVHLDSQNEATIVIESKVDATKPNL--FVILVKYY 1244

Mouse  1312 QPVHPSFPVEVLINGGR-IWQGHANASFCPHGYGCRTLVLCEGQTMLDVTDNELTVTVRVPEGRW 1375
            ||.||.:.|...:..|: .:.|..:...||...|||.::...|:...:: |:|...|:.....:.
  Fly  1245 QPSHPKYQVYYTLTAGKNQYDGKFDIQHCPSSSGCRGVIRPAGEGSFEI-DDEFKFTITTDRSQS 1308

Mouse  1376 LWLDYVLIVPEDAYSSSYLQEEPLDKSYDFISHCATQGYHISPSSSSPFCRNAATSLSLFYNNGA 1440
            :||||:::||...|:...|.||..|::.:||.:|....:||: .::|.||:.:..||:..||:||
  Fly  1309 VWLDYLVVVPLKQYNDDLLVEETFDQTKEFIQNCGHDHFHIT-HNASDFCKKSVFSLTADYNSGA 1372

Mouse  1441 LPCGCHEVGAVSPTCEPFGGQCPCRGHVIGRDCSRCATGYWGFPNCRPCDC-GARLCDELTGQCI 1504
            |||.|...|:.|..|.||||||.|:.:||.|.|..|.:.|:|||:|:||.| .:.:|:..||:|:
  Fly  1373 LPCNCDYAGSTSFECHPFGGQCQCKPNVIERTCGACRSRYYGFPDCKPCKCPNSAMCEPTTGECM 1437

Mouse  1505 CPPRTVPPDCLVCQPQSFGCHPLVGCEECNCSGPGVQELTDPTCDMDSGQCRCRPNVAGRRCDTC 1569
            |||..:...|..|.|.::|.|.::|||||.|:..|:.. .:..||:.:|.|.||.|:.||.||.|
  Fly  1438 CPPNVIGDLCEKCAPNTYGFHQVIGCEECACNPMGIAN-GNSQCDLFNGTCECRQNIEGRACDVC 1501

Mouse  1570 APGFYGYPSCRPCDCHEAGTMASVCDPLTGQCHCKENVQGSRCDQCRVGTFSLDAANPKGCTRCF 1634
            :.|::.:|.|..|.||:.||...|||.:.|.|.||:||.|..||||..||::|..:||.|||.||
  Fly  1502 SNGYFNFPHCEQCSCHKPGTELEVCDKIDGACFCKKNVVGRDCDQCVDGTYNLQESNPDGCTTCF 1566

Mouse  1635 CFGATERCG-------NSNLARH------EFVDMEGWVLLSSDRQVVPHEHRPEIEL----LHAD 1682
            |||.|.||.       |.:|.:|      ||.:..    :..|...||.:   ||.|    |.||
  Fly  1567 CFGKTSRCDSAYLRVYNVSLLKHVSITTPEFHEES----IKFDMWPVPAD---EILLNETTLKAD 1624

Mouse  1683 --LRSVADTFSELYWQAPPSYLG---------DRVSSYGGTLHYELHSETQRGDIFIPYESRPDV 1736
              ||.|.|        ..|:|.|         :.:|:|||.|.|.||..:.....:|   ..|||
  Fly  1625 FTLREVND--------ERPAYFGVLDYLLNQNNHISAYGGDLAYTLHFTSGFDGKYI---VAPDV 1678

Mouse  1737 VLQGNQMSIAFLELAYPPPGQVHRGQLQLVEGNFRHLETHNPVSREELMMVLAGLEQLQIRALFS 1801
            :|.....::.......|...:....::.:||.||:.: :..||||.:.||||..|:.:.|||.:.
  Fly  1679 ILFSEHNALVHTSYEQPSRNEPFTNRVNIVESNFQTI-SGKPVSRADFMMVLRDLKVIFIRANYW 1742

Mouse  1802 QTSSSVSLRRVVLEVASEAGRGPPASN---VELCMCPANYRGDSCQECAPGYYRDTKGLFLGRCV 1863
            :.:....|..|.|.:|.|...|.....   ||.|.||..|.|.||::||||||||..|.:.|.|:
  Fly  1743 EQTLVTHLSDVYLTLADEDADGTGEYQFLAVERCSCPPGYSGHSCEDCAPGYYRDPSGPYGGYCI 1807

Mouse  1864 PCQCHGHSDRCLPGSGICVGCQHNTEGDQCERCRPGFVSSDPSNPASPCVSCPCPLAVPSNNFAD 1928
            ||:|:|||:.|...:|||..|||.||||.||||..|:..:..:.....|:.|.|||...|||||.
  Fly  1808 PCECNGHSETCDCATGICSKCQHGTEGDHCERCVSGYYGNATNGTPGDCMICACPLPFDSNNFAT 1872

Mouse  1929 GCVLRNGRTQ--CLCRPGYAGASCERCAPGFFGNPLVLGSSCQPCDCSGNGDPNMIFSDCDPLTG 1991
            .|.:.....|  |.|:|||.|..||.||.||:|.|..:|..|:||:||||.:|....| ||..||
  Fly  1873 SCEISESGDQIHCECKPGYTGPRCESCANGFYGEPESIGQVCKPCECSGNINPEDQGS-CDTRTG 1936

Mouse  1992 ACRGCLRHTTGPHCERCAPGFYGNALLPGNCTRCDCSPCGTETCDPQSGRCLCKAGVTGQRCDRC 2056
            .|..||.:|.|..|..|||||||:|:...||..|||...||:||||..|.|.|...|.|.|||||
  Fly  1937 ECLRCLNNTFGAACNLCAPGFYGDAIKLKNCQSCDCDDLGTQTCDPFVGVCTCHENVIGDRCDRC 2001

Mouse  2057 LEGYFGFEQCQGCRPCACGPAAKGSECHPQSGQCHCQPGTTGPQCLECAPGYWGLPEKGCRRCQC 2121
            ...::|||...|||.|.||.|:..::|.|.:|.|.|:.|.||.||..||..:|...:.||..|.|
  Fly  2002 KPDHYGFESGVGCRACDCGAASNSTQCDPHTGHCACKSGVTGRQCDRCAVDHWKYEKDGCTPCNC 2066

Mouse  2122 PRGH-----CDPHTGHCTCPPGLSGERCDTCSQQHQVPVPGKPGGHGIHCEVCDHCVVLLLDDLE 2181
            .:|:     |:|:||.|.|.||:.|:|||.|..:.   |..|..|    |:.|::|...|||..:
  Fly  2067 NQGYSRGFGCNPNTGKCQCLPGVIGDRCDACPNRW---VLIKDEG----CQECNNCHHALLDVTD 2124

Mouse  2182 RAGALLPAIREQLQGINASSAAWARLHRLN-----ASIADLQSKLRSPPGPRYQAAQQLQTLEQQ 2241
            |....:.::   |:..|:.:.|:....:||     |...:.:.||..|      .:..|...::.
  Fly  2125 RMRYQIDSV---LEDFNSVTLAFFTSQKLNYYDQLADELEPKVKLLDP------NSVDLSPSKKA 2180

Mouse  2242 SISLQQDTERLGSQATGVQGQAGQLLDTTESTLGRAQKLLESVRAVGRALNELASRMGQGSPGDA 2306
            :..|:.|.:....|.......|..:.:.:.:|||......                       |.
  Fly  2181 NSELESDAKSYAKQVNQTLANAFDIRERSSTTLGNITVAY-----------------------DE 2222

Mouse  2307 LVPSGEQLRWALAEVERLLWDMRTRDLGAQGAV-AEAELAEAQRLMARVQ-------------EQ 2357
            .|.|.:|.:.|:|.||.|     :::|.|..:. .:|.|.:||.::.::.             |:
  Fly  2223 AVKSADQAKEAIASVEAL-----SKNLEAAASTKIDAALEQAQHILGQINGTSIELTPNEQVLEK 2282

Mouse  2358 LTSFWEENQSLATHIRDQ---LAQYESGLMDLREALNQAVNTTREAEELNSRNQERLKEALQWKQ 2419
            ....:||..:|...|:.|   |...::.:.:..:.|....|.: ||.:..|.:.||...|.|...
  Fly  2283 ARKLYEEVNTLVLPIKAQNKSLNALKNDIGEFSDHLEDLFNWS-EASQAKSADVERRNVANQKAF 2346

Mouse  2420 ELSQDNATLKATLQA-------------ASLILGHVSELLQGIDQAKEDLEHLAASLDGAWTPLL 2471
            :.|:.:...:..|||             ..|.|..:::.|..:..|..:|.....::|   ..|.
  Fly  2347 DNSKFDTVSEQKLQAEKNIKDAGNFLINGDLTLNQINQKLDNLRDALNELNSFNKNVD---EELP 2408

Mouse  2472 KRMQAFSPASSKVDLVEAAEAHAQKLNQLAINLSGIILG-INQDRFIQRAVEASNAYSSILQAVQ 2535
            .|......|.:..|..|      ||..:|||....:... .:.....:.|::|:.|||.|::||:
  Fly  2409 VREDQHKEADALTDQAE------QKAAELAIKAQDLAAQYTDMTASAEPAIKAATAYSGIVEAVE 2467

Mouse  2536 AAEDAAGQALRQASRTWEM---VVQRGLAA--GARQLLANS-SALEETILGHQGRLGLAQGRLQA 2594
            ||:..:..|:..|....:.   :.:|...|  |:..||..: .:|::.....:.||..:.|::|
  Fly  2468 AAQKLSQDAISAAGNATDKTDGIEERAHLADTGSTDLLQRARQSLQKVQDDLEPRLNASAGKVQ- 2531

Mouse  2595 AGIQLHNVWARKNQLAAQIQEAQAMLAMDTSETSEKI-AHAKAVAAEALSTATHVQSQLQGMQKN 2658
                  .:.|..|....|:::...::....:|:...: .::.|.|::||....:|...|:.:...
  Fly  2532 ------KISAVNNATEHQLKDINKLIDQLPAESQRDMWKNSNANASDALEILKNVLEILEPVSVQ 2590

Mouse  2659 VERWQSQLGG------LQGQDLSQVER---DASSSVSTLEKTLPQLLAKLSRLENRGVHNASLAL 2714
            ..:...:..|      |..:|:||..:   |...|||.|.    :|...:...::| |.:.|..|
  Fly  2591 TPKELEKAHGINRDLDLTNKDVSQANKQLDDVEGSVSKLS----ELAEDIEEQQHR-VGSQSRQL 2650

Mouse  2715 SANIGRVRKLIAQARSAASKVKVSMKFNGRSGVRLRTPRDLADLAAYTALKFHIQSPVPAPEPGK 2779
            ...|..::..:..||..|:.:||.:.|...:.:.|:||.....||..|.|..:.::..|:
  Fly  2651 GQEIENLKAQVEAARQLANSIKVGVNFKPSTILELKTPEKTKLLATRTNLSTYFRTTEPS----- 2710

Mouse  2780 NTGDHFVLYMG----SRQATGDYMGVSLRNQKVHWVYRLGKAGPTTLSIDENI--GEQFAAVSID 2838
                .|:||:|    :.|...|::.|.:.|........||. ||..::.|:.:  |..:.|| :|
  Fly  2711 ----GFLLYLGNDNKTAQKNNDFVAVEIVNGYPILTIDLGN-GPERITSDKYVADGRWYQAV-VD 2769

Mouse  2839 RTLQFG-HMSVTVEKQMVHEIKGDTVAPGSEGLLN-----LHPD-DFVFYVGGYP--SNFTPPEP 2894
            |   .| :..:|:.:::.:   ||.|.....|.|.     ||.| :...:|||||  |:|..|..
  Fly  2770 R---MGPNAKLTIREELPN---GDVVEHSKSGYLEGSQNILHVDKNSRLFVGGYPGISDFNAPPD 2828

Mouse  2895 LRFPGYLGCIEMETLNEEVVSLYNF-----------EQTFMLDTAVDKPCARSKATGDPWLTDGS 2948
            |....:.|.||...:.:|.|.|:||           |:..:|:........|.|..|...|...|
  Fly  2829 LTTNSFSGDIEDLKIGDESVGLWNFVYGDDNDQGARERDVLLEKKKPVTGLRFKGNGYVQLNATS 2893

Mouse  2949 YLDGSGFARISFEKQFSNTKRFDQELRLVSYNGIIFFLKQESQFLCLAVQEGTLVLFYDFGSGLK 3013
            .|......:.||        :.|::    :.||::||..::..::.:.:.:|  .:|::...|
  Fly  2894 NLKSRSSIQFSF--------KADKD----TSNGLLFFYGRDKHYMSIEMIDG--AIFFNISLG-- 2942

Mouse  3014 KADPLQPPQALTAASKAVRQGRGLGMGGPAEKFGFPVPATHPLQIQVFLLAGNRKRVL----VRV 3074
                               :|.|: ..|..:::.  ....|.:|.:    ..||..:|    :.:
  Fly  2943 -------------------EGGGV-QSGSQDRYN--DNQWHKVQAE----RENRNGLLKVDDIVI 2981

Mouse  3075 ERATVFSVDQDNMLEMADAYYLGGVPPE-QLPLSLRQLFPSGGSVRGCIKGIKALGKYVDLKRLN 3138
            .| |...::.|..|......|.||.|.. ...:||:..|.      |||..:......|||....
  Fly  2982 SR-TNAPLEADLELPKLRRLYFGGHPRRLNTSISLQPNFD------GCIDNVVINQGVVDLTEYV 3039

Mouse  3139 T-TGISFGCTADLLVGRTMTFHGHGFLPLALPDVAPITEVVYSGFGFRGTQDNNLLYYRTSPD-- 3200
            | .|:..||:|......:...|.:|||.:..........||   ..|:.||.|.:|:|..:.|
  Fly  3040 TGGGVEEGCSAKFSTVVSYAPHEYGFLRMNNVSSDNNLHVV---LHFKTTQPNGVLFYAANHDQS 3101

Mouse  3201 GPYQVSLREGHVTLRFM-NQEVETQRVFADGAPHYVAFYSNVTGVWLYVDDQLQLVKSHERTTPM 3264
            ....:||::|.:.|..| :|.|...|:..||..|.|........:.|.|||    |.:....:|
  Fly  3102 STIGLSLQDGLLKLNSMGSQLVIDDRILNDGEDHVVTVQHTQGELRLTVDD----VDNKRLGSP- 3161

Mouse  3265 LQLQP--EEPSRLLLGGLP--------VSGTFHNFSGCISNVFVQRLRGPQRVFDL----HQNMG 3315
               ||  .|...:...|||        ...:...|.||||:|.|.     :.:.:.    .:..|
  Fly  3162 ---QPLILEGGDIFFAGLPDNYRTPRNALASLAYFVGCISDVTVN-----EEIINFANSAEKKNG 3218

Mouse  3316 SVNVSVGC--------------------------------------------------------- 3323
            ::|   ||
  Fly  3219 NIN---GCPPHVLAYEPSLVPSYYPSGDNEVESPWSNADTLPPLKPDIESTLPPTTPTTTTTTTT 3280

Mouse  3324 ---------------TPAQLI-----ETSRATAQKVSRRSRQPSQ-----DLACTTPWLPGTIQD 3363
                           ||:.::     |....|.||: ..:|.|::     |..|..|..|....|
  Fly  3281 TTTSTTTTSTTTTTTTPSPIVIDEEKEIEAKTPQKI-LTTRPPAKLNLPSDERCKLPEQPNFDVD 3344

Mouse  3364 AYQFGGPLPSYLQFVGISPSHRNRLHLSML---VRPH---------AASQGLLLSTAPMSGRSPS 3416
            ..:.|      .:|.|:   ...||.::.|   ||.|         ....|||: .|....|...
  Fly  3345 FTEAG------YRFYGL---REQRLQINSLPVKVRRHHDIGISFRTERPNGLLI-YAGSKQRDDF 3399

Mouse  3417 LVLFLNHGHFVAQTEGPGPRLQ--VQSRQHSRAGQWHRVSVRWGMQQIQLVVDGSQTWSQKALHH 3479
            :.::|..|....:.. .|.:||  :.:......|.||.|.|....:::.|::|..:......|:
  Fly  3400 IAVYLLDGRVTYEIR-VGAQLQAKITTEAELNDGTWHTVEVVRTQRKVSLLIDKLEQPGSVDLN- 3462

Mouse  3480 RVPRAERPQP-----YTLSVGGL---------PASSYSSKLPVSVGFSGCLKKLQLDKRPLRTPT 3530
                |||..|     ..:.:||:         ..:.:.:::|.   |:||||.::.|...|.||.
  Fly  3463 ----AERSAPVLAVELPIYLGGVNKFLESEVKNLTDFKTEVPY---FNGCLKNIKFDAMDLETPP 3520

Mouse  3531 QMVGVTPCVSGPLEDGLFFPGSEGVVTL--------ELPKAKMPYVSLELEMRPLAAAGLIF--H 3585
            :..||.|| |..:|.||||...:..|.:        |:        .:..:.||....||:|  |
  Fly  3521 EEFGVVPC-SEQVERGLFFNNQKAFVKIFDHFDVGTEM--------KISFDFRPRDPNGLLFSVH 3576

Mouse  3586 LGQALA-------TPYMQLKVLTEQVLLQANDGAGEFSTWVTYP---KLCDGRWHRVAVIMGRDT 3640
            ...:.|       |.|..:|...:.::          ||....|   ..|||:...|..|..:..
  Fly  3577 GKNSYAILELVDNTLYFTVKTDLKNIV----------STNYKLPNNESFCDGKTRNVQAIKSKFV 3631

Mouse  3641 LRLEVD-TQSNHTTGRLPESLAGSPALLHLGS------LPKSSTARPELPAYRGCLRKLLINGAP 3698
            :.:.|| ..||...|.....:..:...|.||.      .|...|.:    :::||:.|:.:|...
  Fly  3632 INIAVDFISSNPGVGNEGSVITRTNRPLFLGGHVAFQRAPGIKTKK----SFKGCISKVEVNQRM 3692

Mouse  3699 VNVTASVQIQGAVGMRGCP 3717
            :|:|.:: :.|.:....||
  Fly  3693 INITPNM-VVGDIWQGYCP 3710

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Lama5	XP_006500638.1	Laminin_N	59..303	CDD:365840	137/244 (56%)
		EGF_Lam	304..352	CDD:238012	30/48 (63%)
		EGF_Lam	363..426	CDD:238012	30/62 (48%)
		EGF_Lam	433..474	CDD:238012	18/40 (45%)
		EGF_Lam	500..547	CDD:214543	21/47 (45%)
		EGF_Lam	546..589	CDD:238012	16/42 (38%)
		Laminin_EGF	593..640	CDD:365839	25/47 (53%)
		Laminin_EGF	638..685	CDD:365839	16/46 (35%)
		EGF_Lam	682..724	CDD:238012	19/41 (46%)
		EGF_Lam	781..832	CDD:238012	22/51 (43%)
		EGF_Lam	833..>872	CDD:238012	14/38 (37%)
		Laminin_EGF	1443..1491	CDD:365839	24/47 (51%)
		Laminin_EGF	1533..1584	CDD:365839	19/50 (38%)
		Laminin_EGF	1582..1630	CDD:365839	24/47 (51%)
		Laminin_B	1694..1830	CDD:365838	39/147 (27%)
		EGF_Lam	1864..>1900	CDD:238012	21/35 (60%)
		Laminin_EGF	1915..1968	CDD:365839	26/54 (48%)
		EGF_Lam	1970..2023	CDD:238012	27/52 (52%)
		EGF_Lam	2025..2069	CDD:214543	22/43 (51%)
		EGF_Lam	2071..2117	CDD:238012	18/45 (40%)
		Laminin_EGF	2119..>2147	CDD:365839	15/32 (47%)
		Laminin_I	2194..2452	CDD:310534	55/292 (19%)
		DUF3584	<2355..>2618	CDD:378817	61/298 (20%)
		Laminin_II	2642..2764	CDD:368703	31/130 (24%)
		LamG	2783..2912	CDD:214598	40/143 (28%)
		LamG	2969..3130	CDD:214598	30/165 (18%)
		LamG	3182..3300	CDD:214598	38/130 (29%)
		LamG	3364..3522	CDD:238058	39/185 (21%)
		LamG	3569..3696	CDD:214598	31/145 (21%)
LanA	NP_476617.1	LamNT	18..271	CDD:214532	145/253 (57%)
		EGF_Lam	272..>314	CDD:238012	26/41 (63%)
		EGF_Lam	332..389	CDD:238012	29/56 (52%)
		EGF_Lam	402..443	CDD:238012	18/40 (45%)
		EGF_Lam	448..491	CDD:238012	19/43 (44%)
		Laminin_EGF	495..543	CDD:278482	19/47 (40%)
		Laminin_EGF	541..589	CDD:278482	25/47 (53%)
		Laminin_EGF	587..634	CDD:278482	16/46 (35%)
		EGF_Lam	631..673	CDD:238012	20/42 (48%)
		Laminin_EGF	677..729	CDD:278482	19/52 (37%)
		Laminin_EGF	732..782	CDD:278482	21/49 (43%)
		EGF_Lam	785..828	CDD:238012	16/42 (38%)
		CBM6-CBM35-CBM36_like	831..966	CDD:271143	47/139 (34%)
		Laminin_EGF	1375..1423	CDD:278482	24/47 (51%)
		EGF_Lam	1420..1457	CDD:238012	13/36 (36%)
		Laminin_EGF	1466..1516	CDD:278482	19/50 (38%)
		Laminin_EGF	1514..1562	CDD:278482	24/47 (51%)
		LamB	1632..1760	CDD:214597	38/139 (27%)
		Laminin_EGF	<1775..1801	CDD:278482	15/25 (60%)
		EGF_Lam	1808..1851	CDD:238012	22/42 (52%)
		EGF_Lam	1859..1907	CDD:214543	24/47 (51%)
		EGF_Lam	1916..1968	CDD:238012	27/52 (52%)
		EGF_Lam	1969..2015	CDD:238012	23/45 (51%)
		EGF_Lam	2016..>2054	CDD:238012	16/37 (43%)
		EGF_Lam	2063..>2097	CDD:238012	15/33 (45%)
		Laminin_I	2129..2385	CDD:283627	54/293 (18%)
		Tar	2278..2662	CDD:223910	84/405 (21%)
		Laminin_II	2566..2700	CDD:283628	34/138 (25%)
		LamG	2674..2843	CDD:238058	49/185 (26%)
		LamG	2878..3029	CDD:238058	38/199 (19%)
		LamG	3078..3205	CDD:214598	40/142 (28%)
		LamG	3349..3512	CDD:238058	39/181 (22%)
		LamG	3535..3689	CDD:238058	37/175 (21%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	301	1.000	Domainoid score	I1408
eggNOG	1	0.900	-	-		E1_KOG1836
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H4060
Inparanoid	1	1.050	1791	1.000	Inparanoid score	I65
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG45870
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0003375
OrthoInspector	1	1.000	-	-		oto95121
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R2298
SonicParanoid	1	1.000	-	-		X3259
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	12	11.860