| Sequence 1: | NP_001918.3 | Gene: | DES / 1674 | HGNCID: | 2770 | Length: | 470 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001260974.1 | Gene: | LamC / 36615 | FlyBaseID: | FBgn0010397 | Length: | 640 | Species: | Drosophila melanogaster |
| Alignment Length: | 419 | Identity: | 128/419 - (30%) |
|---|---|---|---|
| Similarity: | 216/419 - (51%) | Gaps: | 69/419 - (16%) |
- Green bases have known domain annotations that are detailed below.
|
Human 48 SVTSRVYQVSRTSGGAGGLGSLRASRLGTTRTPSSYGAGELLDFSLADAVNQEFLTTRTNEKVEL 112
Human 113 QELNDRFANYIEKVRFLEQQNAALAAEVNRLK---GREPTRVAELYEEELRELRRQVEVLTNQRA 174
Human 175 RVDVERDNLLDDLQRLKAKLQEEIQLKEEAENN-------------------------------- 207
Human 208 ----------LAAFRADVDAATLARIDLERRIESLNEEIAFLKKVHEEEIRELQAQLQEQQVQVE 262
Human 263 MDMSK---PDLTAALRDIRAQYETIAAKNISEAEEWYKSKVSDLTQAANKNNDALRQAKQEMMEY 324
Human 325 RHQIQSYTCEIDALKGTNDSLMRQMRELEDRFASEASGYQDNIARLEEEIRHLKDEMARHLREYQ 389
Human 390 DLLNVKMALDVEIATYRKLLEGEESRINL 418 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DES | NP_001918.3 | head | 1..107 | 15/58 (26%) | |
| Head | 2..108 | 15/59 (25%) | |||
| Filament_head | 9..106 | CDD:309741 | 14/57 (25%) | ||
| Filament | 107..415 | CDD:306535 | 111/355 (31%) | ||
| rod | 108..411 | 108/350 (31%) | |||
| Coil 1A | 109..141 | 17/31 (55%) | |||
| Linker 1 | 142..151 | 2/11 (18%) | |||
| Coil 1B | 152..252 | 34/141 (24%) | |||
| Linker 12 | 253..268 | 2/17 (12%) | |||
| Interaction with NEB. /evidence=ECO:0000269|PubMed:23615443 | 268..415 | 54/146 (37%) | |||
| Coil 2A | 269..287 | 6/17 (35%) | |||
| Linker 2 | 288..295 | 3/6 (50%) | |||
| Coil 2B | 296..412 | 42/115 (37%) | |||
| tail | 412..469 | 4/7 (57%) | |||
| Tail | 413..470 | 3/6 (50%) | |||
| Interaction with CRYAB. /evidence=ECO:0000269|PubMed:28470624 | 438..453 | ||||
| LamC | NP_001260974.1 | Filament | 45..401 | CDD:278467 | 111/355 (31%) |
| ATP-synt_B | <67..>142 | CDD:304375 | 18/74 (24%) | ||
| MreC | <178..>224 | CDD:302802 | 16/45 (36%) | ||
| LTD | 473..574 | CDD:279300 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E1_KOG0977 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 0 | 0.000 | Not matched by this tool. | |||
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 2 | 1.810 | |||||