| Sequence 1: | NP_001918.3 | Gene: | DES / 1674 | HGNCID: | 2770 | Length: | 470 | Species: | Homo sapiens |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_476616.1 | Gene: | Lam / 33782 | FlyBaseID: | FBgn0002525 | Length: | 622 | Species: | Drosophila melanogaster |
| Alignment Length: | 156 | Identity: | 39/156 - (25%) |
|---|---|---|---|
| Similarity: | 53/156 - (33%) | Gaps: | 47/156 - (30%) |
- Green bases have known domain annotations that are detailed below.
|
Human 2589 GNIPTTHPLMVRHADHSSLTLGSGSSTTRLTQGIGRSQRTL-RQLTANTGHTIHVHYPGNRQPNP 2652
Human 2653 PLILQRLLGPSAAADILQ-----LSSSLPLQSRGRARLLVGND---DVHIIARSDDELLDDFFHD 2709
Human 2710 QSTATSQAGTLSSIPTALTRWTEECK 2735 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| DES | NP_001918.3 | head | 1..107 | ||
| Head | 2..108 | ||||
| Filament_head | 9..106 | CDD:461414 | |||
| Filament | 107..415 | CDD:459643 | |||
| rod | 108..411 | ||||
| Coil 1A | 109..141 | ||||
| Linker 1 | 142..151 | ||||
| Coil 1B | 152..252 | ||||
| Linker 12 | 253..268 | ||||
| Interaction with NEB. /evidence=ECO:0000269|PubMed:23615443 | 268..415 | ||||
| Coil 2A | 269..287 | ||||
| Linker 2 | 288..295 | ||||
| Coil 2B | 296..412 | ||||
| tail | 412..469 | ||||
| Tail | 413..470 | ||||
| Interaction with CRYAB. /evidence=ECO:0000269|PubMed:28470624 | 438..453 | ||||
| Lam | NP_476616.1 | Filament | 54..409 | CDD:459643 | 23/91 (25%) |
| LTD | 467..572 | CDD:460003 | |||
| Blue background indicates that the domain is not in the aligned region. | |||||