Protein Alignment Ktn1 and alt

DIOPT Version :9

• Sequence 1: NP_032503.2
• Gene: Ktn1 / 16709
• MGIID: 109153
• Length: 1327
• Species: Mus musculus
• Sequence 2: NP_001262679.1
• Gene: alt / 42127
• FlyBaseID: FBgn0038535
• Length: 874
• Species: Drosophila melanogaster
• Alignment Length: 1259
• Identity: 246/1259 - (19%)
• Similarity: 459/1259 - (36%)
• Gaps: 423/1259 - (33%)

Mouse     8 YFVVLIPSVVITVI--FLFFWLFMKETLYDEVLAKQKREQKLISTKTDKKK--AEKKKNKKKEIQ 68
            :.:::|..||...:  |||.....:...::||:|    |::.:|....|..  |..||.||||::
  Fly     4 HILIVIGCVVSASLLSFLFINKIFRRKTFEEVVA----EKRALSANLYKAAGGAATKKPKKKELK 64

Mouse    69 NGTLRESDSEHVPRDFKLSDASPAEDEQFVPAPLNVAETSSSVRERKKKEKKQKPSLEEQVIK-E 132
                         |:.|........|....|.|....:.|....|.:.....::|.|.:|.:: |
  Fly    65 -------------REKKQRQREQQRDVNNEPEPEEAEDYSDGQSEGQGSVAGEEPGLSKQHVEFE 116

Mouse   133 SDASKIPGKKVEPVLVTKQPAPPPPLEAAALKKKAGQKKSKNGSEEQDKKVEMLMAPSKEQDVLL 197
            .||..:..::....:..|:..|     :.|.||  |:|..:||            |.:|...:|:
  Fly   117 PDAEVLTDQRRPSSVAEKENQP-----SGAGKK--GKKDKRNG------------ANNKTAGILV 162

Mouse   198 SHQDTKQEGGLGKKKGLSKKQKSENVAVLVDEPLIHATTYIPLDNANSNLMMDKREIIDMIKPDH 262
            :                    |:|.|||   :|..:|.....|:|..:.:..|..|
  Fly   163 N--------------------KNETVAV---KPAANAEETPTLNNFETKIPKDVVE--------- 195

Mouse   263 VEGIQKSGTKKLKIETDKENAEVKFKDFLLSLKTMMFSEDEALCVVDLLKEKSGVIKEALKKSNK 327
                       ||.:..||.                             ||.:...:::.||...
  Fly   196 -----------LKKQEQKER-----------------------------KEDNNNKQQSQKKIAG 220

Mouse   328 GELSGLLHQLQEKERLLSAMKEDAAASKERCKQLTQEMMTEKERSSVVIARMKDRIGTLEKEHNI 392
            |.:|       :||::::...|....:|:..||..|:                 :.|:.:.:||.
  Fly   221 GNVS-------KKEKVVAVETEAPVVTKQILKQQQQQ-----------------QNGSPKTQHNQ 261

Mouse   393 FQNKMHASYQETQQMQMKFQQVQEQMEA-EIAHLKQENGILRDAVSNTTNQLESKQSAELNKLRQ 456
            ..||      ..||.|.|.|..:|.:.. ::||       ..|.:::..|     |:..:|.|..
  Fly   262 ANNK------TKQQQQNKKQNQKETLTGKDLAH-------ALDKLADHQN-----QTIGVNALMN 308

Mouse   457 DCGRLVSELNEKTGKLQQEGVQKKNAEQAATQLKVQLQEAERRWEEVQSYIRKRTAEHEAAQQDL 521
            ...|  :|||.                                 .|:|..|
  Fly   309 VFSR--AELNR---------------------------------SEIQILI-------------- 324

Mouse   522 QSKFVAKENEVQSLHSKLTDTLVSKQQLEQRLMQLMESEQKRASKEESLQIQVQDILEQNEALKA 586
             ...:.|:.::.:.||:.:|.:.      |:|.:.:|.::|..::|:...|.:|..|.:   |:.
  Fly   325 -DYLLNKQQDMPASHSEWSDDIC------QKLKRQLEEKEKLLAEEQEASIGIQAKLRE---LRQ 379

Mouse   587 QIQQFHSQIAAQTSASVLAEELHKVIAEKDKQLKQTEDSLANEQDHLASKEEELKDVQNMNFLLK 651
            ::....:|:.|:..|.:                    |.|..::..||:..:||   .::|..|.
  Fly   380 EVNTERAQMHARNQAYI--------------------DKLQGKEQELAALNQEL---SSLNDKLT 421

Mouse   652 AEVQKLQALANEQAATAHEVEKMQKSIHVKEDKIRLLEEQLQHEVASKMEELKILSEQNKALQSE 716
            .|.|:|..|..|:.|.:.::.::|   |:::|        |.|:.       |.|:|....:.:|
  Fly   422 LERQQLTTLRREKQANSQDLVQLQ---HLQQD--------LAHKE-------KCLAEMTAFVNAE 468

Mouse   717 VQKLQTAVSQQPNKDVVEQMEKCIQEKDEKLRTVEELLETGLIQVATREEELSAIRTENSTLTRE 781
            .|                |..:.||::.::|:.:|                          |.||
  Fly   469 TQ----------------QKNEVIQQQAQQLQALE--------------------------LQRE 491

Mouse   782 VQELKAKQSDQVSFVSLIEDLKRVIHEKDGQIKSVEELLEVELLKVANKEKTVQALKQEIEVLKE 846
              ||:|:|::                       |:.||.:.:.|:..|.:     ||||:..:::
  Fly   492 --ELEARQNN-----------------------SIFELEQRKQLEAENAD-----LKQELSAVQQ 526

Mouse   847 EIGNAQLEKAHQLSVTSQVQEL-QNLLRGKEEQVNSMKAALEDRDRDLRGRGTCAQVCSTPQFEE 910
            .  .::|::.|    .:::||| |||     ..:.:...||..:..........|....:.|.:.
  Fly   527 T--QSELQRVH----AAELQELRQNL-----SVLEARNVALSQQLTQAANSAVQATAAQSEQAQV 580

Mouse   911 LESVLKEKDNEIKRIEVKLKDTESDVSKMSELLKEVQEENKFLKCQLSHQKHQQASFPSQEELQT 975
            ....|.:|..|:..:       .|.|..:::...:.|::...|:.||  |:.||.:    |:||.
  Fly   581 QTEALAQKQQELSAL-------RSQVGSLTDAHAQQQKQANALQSQL--QEAQQRA----EQLQA 632

Mouse   976 VISEKEKEITDLCNELESLKNAVEHQRKKNNDLREKNWEAMEALASTEKMLQDRVNKTSKERRQH 1040
                  ||        :.|:..::.||:||||:|.|||:.:|||.:.|.:       |:|.:...
  Fly   633 ------KE--------QHLQQELQEQREKNNDVRMKNWKLIEALQNAEAL-------TAKTKTNS 676

Mouse  1041 VEAIELESKDLLKRLFPTVSVPSNLNYSEWLRGFEKKAKACVAGTSDAEAVKVLEHRLKEASEMH 1105
            .:::..:.|:|..:                    ::||.|...|.| |.:.|..:.|::   :::
  Fly   677 AQSVGQQHKELQLQ--------------------QQKAVAANGGGS-ASSAKSEQQRIR---DLY 717

Mouse  1106 TLLQLECEKYKS----VLAETEGILQKLQRSVEQEESKWKIKADESQRMIKQMQSSFTASERELE 1166
            ..|..:..|.:|    ..:..:.:.|.|...|:|::.|.:.|.| :::..||..||..:::....
  Fly   718 QRLYPDAVKAQSGNALQASFDQWLEQVLATHVKQQQDKLRQKLD-AEKSEKQSSSSHKSTQSSNS 781

Mouse  1167 RLRQENKDMENLRREREHLEME----LEKAEMERSTYVMEVRELKDLLTELQKKL---------- 1217
            .....|....|:.........:    .|:.|:.:..  :::||..|.||:|..|.
  Fly   782 SSSNHNSTHNNISSNNSSSNSQSSSAAEQQELHKQN--LQLRECNDKLTQLVTKTTNTLMDLEER 844

Mouse  1218 ----DDSYSEAVRQNEELNLLKTQ 1237
                |:.:...|.|.|:|.|...|
  Fly   845 AREQDEHWRGIVEQKEQLILTLQQ 868

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ktn1	NP_032503.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	49..181		31/134 (23%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	197..216		0/18 (0%)
		SMC_prok_A	<311..617	CDD:274009	54/306 (18%)
		SMC_prok_B	483..1273	CDD:274008	152/778 (20%)
alt	NP_001262679.1	SMC_prok_B	<398..694	CDD:274008	92/453 (20%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	148	1.000	Inparanoid score	I4381
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	2.050