DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment cob and CYTB

DIOPT Version :9

Sequence 1:	NP_039502.1	Gene:	cob / 1669523	-ID:	-	Length:	387	Species:	Schizosaccharomyces pombe
Sequence 2:	YP_009047277.1	Gene:	CYTB / 19893556	FlyBaseID:	FBgn0013678	Length:	378	Species:	Drosophila melanogaster

Alignment Length:	360	Identity:	185/360 - (51%)
Similarity:	253/360 - (70%)	Gaps:	2/360 - (0%)

- Green bases have known domain annotations that are detailed below.

pombe     6 SNPFLALANNYMIDAPEPSNISYFWNFGSLLACVLVIQIVIGILLACFYIPNMDLAFLSVERIVR 70
            |:|...:|||.::|.|.|.|||.:|||||||...|:|||:.|:.||..|..:::|||.||..|.|
  Fly     8 SHPLFKIANNALVDLPAPINISSWWNFGSLLGLCLIIQILTGLFLAMHYTADINLAFYSVNHICR 72

pombe    71 DVNYGFLLRAFHANGASFFFIFLYLHIGRGLYYGSYKYPRTMTWNIGVIIFLLTIITAFLGYCLP 135
            |||||:|||..||||||||||.:|||:|||:||||||:  |.||.|||||..|.:.|||:||.||
  Fly    73 DVNYGWLLRTLHANGASFFFICIYLHVGRGIYYGSYKF--TPTWLIGVIILFLVMGTAFMGYVLP 135

pombe   136 ANQMSFWGATVITNLLSAVPFIGDDLVHLLWGGFSVSNPTLNRFFSLHYLMPFVIAALSVMHLIA 200
            ..||||||||||||||||:|::|.|||..|||||:|.|.||.|||:.|:::||::.|::::||:.
  Fly   136 WGQMSFWGATVITNLLSAIPYLGMDLVQWLWGGFAVDNATLTRFFTFHFILPFIVLAMTMIHLLF 200

pombe   201 LHTNGSSNPLGVTANMDRIPMNPYYLIKDLITIFIFLIGINYMAFYNPYGFMEPDCALPADPLKT 265
            ||..||:||:|:.:|:|:||.:||:..||::...:.:..:..:...:|....:||..:||:||.|
  Fly   201 LHQTGSNNPIGLNSNIDKIPFHPYFTFKDIVGFIVMIFILISLVLISPNLLGDPDNFIPANPLVT 265

pombe   266 PMSIVPEWYLLPFYAILRAIPNFQLGVIAMLLSILVLLLLPLLDFSAIRGNSFNPFGKFFFWTFV 330
            |..|.||||.|..|||||:|||...||||::|||.:|::||..:.|..||..|.|..:..||:.:
  Fly   266 PAHIQPEWYFLFAYAILRSIPNKLGGVIALVLSIAILMILPFYNLSKFRGIQFYPINQVMFWSML 330

pombe   331 ADFVILAWIGGSHPENVFITIGAIATIFYFSYFFI 365
            ...::|.|||....|..::.||.|.|:.||.|:.:
  Fly   331 VTVILLTWIGARPVEEPYVLIGQILTVVYFLYYLV 365

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
cob	NP_039502.1	Cytochrome_b_N	8..207	CDD:238176	120/198 (61%)
		CYTB	10..366	CDD:214440	183/356 (51%)
		Cytochrom_B_C	259..360	CDD:278461	46/100 (46%)
CYTB	YP_009047277.1	CYTB	12..367	CDD:214440	183/356 (51%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	247	1.000	Domainoid score	I418
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	397	1.000	Inparanoid score	I388
OMA	1	1.010	-	-		QHG60605
OrthoFinder	1	1.000	-	-		FOG0004155
OrthoInspector	1	1.000	-	-		oto101666
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	LDO	PTHR19271
Phylome	1	0.910	-	-
RoundUp	1	1.030	-	avgDist	Average_Evolutionary_Distance	R280
SonicParanoid	1	1.000	-	-		X1779
TreeFam	0	0.000	Not matched by this tool.
	10	10.100