DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Krt15 and LamC

DIOPT Version :9

Sequence 1:	NP_032495.2	Gene:	Krt15 / 16665	MGIID:	96689	Length:	456	Species:	Mus musculus
Sequence 2:	NP_001260974.1	Gene:	LamC / 36615	FlyBaseID:	FBgn0010397	Length:	640	Species:	Drosophila melanogaster

Alignment Length:	418	Identity:	124/418 - (29%)
Similarity:	191/418 - (45%)	Gaps:	84/418 - (20%)

- Green bases have known domain annotations that are detailed below.

Mouse    98 EKVTMQNLNDRLASYLDKVRALEQANTELEVKI---RDWYQKQSPASPDRDYSHYFKTMEEIRDK 159
            ||..:|:||||||.|:|::|.||..|:.|..::   :|...:::            ..::.:.:|
  Fly    46 EKEELQHLNDRLACYIDRMRNLENENSRLTQELNLAQDTVNRET------------SNLKAVYEK 98

Mouse   160 ILAAT---IDNS---RVVLEIDNARLAADDFRLK------------YENELTLRQGVEADING-- 204
            .|||.   :|.:   :..||||..||..::..||            .||...|.:....::||
  Fly    99 ELAAARKLLDETAKEKAKLEIDIKRLWEENDDLKPRLDKKTKEATVAENNARLYENRYNEVNGKY 163

Mouse   205 -----------------------LRRVLDEL-------TLARTDLEMQIEQLNEELAYLKKNHEE 239
                                   |||.||:|       ||||.|||.|.:.|.||||:..:.|.:
  Fly   164 NQSLADRKKFEDQAKELALENERLRRQLDDLRKQLEAETLARVDLENQNQSLREELAFKDQVHTQ 228

Mouse   240 EMKEFS-------SQLAGQVNVEMDAAPGVDLTRMLAEMREQYEAIAEKNRRDVEAWFFSKTEEL 297
            |:.|..       |::.|:::.:.:|    .|.:.|.|:|:|||.....||.::|..:.::.:.|
  Fly   229 ELTETRSRRQIEISEIDGRLSRQYEA----KLQQSLQELRDQYEGQMRINREEIELLYDNEIQNL 289

Mouse   298 NKEVASNTEMIQTSKTEITDLRRT-LQGLEIELQSQLSMKAGLENSLAEVECRYATQLQQIQGVI 361
             |..|:.........||...|.|| :.||..:||:.....|||...:.|:|....|:.|:....|
  Fly   290 -KAAANRAAQGSALATEEVRLMRTKIDGLNAKLQNLEDTNAGLNARIRELENLLDTERQRHNQYI 353

Mouse   362 TGLETQLSELRCEMEAQNQEYNMLLDIKTRLEQEIATYRNLLEGQDAKMAGIGVREVSLGGSSGG 426
            ..||.:|..:|.||..|.|||..|:|||..|:.|||.|..||.|::.::     ...|.|..:..
  Fly   354 ASLEAELQRMRDEMAHQLQEYQGLMDIKVSLDLEIAAYDKLLCGEERRL-----NIESPGRPTTD 413

Mouse   427 GGSSSSSSNFHISVEESVDGKVVSSRKR 454
            .|.||:.|:...|. .|..|:|..|.:|
  Fly   414 SGISSNGSHLTASA-SSRSGRVTPSGRR 440

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Krt15	NP_032495.2	Head	1..97
		Filament	97..409	CDD:278467	112/371 (30%)
		Coil 1A	98..133		16/37 (43%)
		Linker 1	134..152		0/17 (0%)
		Coil 1B	153..244		39/140 (28%)
		Linker 12	245..264		3/25 (12%)
		Coil 2	265..406		50/141 (35%)
LamC	NP_001260974.1	Filament	45..401	CDD:278467	112/371 (30%)
		ATP-synt_B	<67..>142	CDD:304375	18/86 (21%)
		MreC	<178..>224	CDD:302802	19/45 (42%)
		LTD	473..574	CDD:279300
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000