Protein Alignment DHX15 and pea

DIOPT Version :10

• Sequence 1: NP_001349.2
• Gene: DHX15 / 1665
• HGNCID: 2738
• Length: 795
• Species: Homo sapiens
• Sequence 2: NP_610928.1
• Gene: pea / 36561
• FlyBaseID: FBgn0086895
• Length: 1242
• Species: Drosophila melanogaster
• Alignment Length: 816
• Identity: 373/816 - (45%)
• Similarity: 503/816 - (61%)
• Gaps: 94/816 - (11%)

Human     7 LDLGEDYPSGKKRAGTDGKDRDRDRDRE-------------------DRSKDRDRERDRG----- 47
            ||..| .|...:..|...||.|.:.|.|                   |.|..|..:...|
  Fly   433 LDRSE-MPDFDEETGLLPKDEDDEADIEIEIVEEEPPFLSGHGRALHDLSPVRIVKNPDGSLAQA 496

Human    48 -------DREREREK--EKEKELRASTNAMLISAGLPPLKASHSAHSTHSAHSTHSTHSAHSTHA 103
                   .:||..:|  ::|:|:.|...: |....:.||....|                .|..|
  Fly   497 AMMQSALSKERREQKMLQREQEIEAMPTS-LNKNWIDPLPEDES----------------RSLAA 544

Human   104 GHAGHTSLPQCINPFTNLPHTPRY-----------------YDILKKRLQLPVWEYKDRFTDILV 151
            ...|..:.|         |..|.:                 ..::::|..||:::.:|.....:.
  Fly   545 NMRGMAAAP---------PEVPEWKKHVIGGKKSSFGKKTDLTLVEQRQSLPIYKLRDDLIKAVT 600

Human   152 RHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRG-VACTQPRRVAAMSVAQRVADEMDVMLGQ 215
            .:|..:::|||||||||||.|    |:.......|| :.|||||||||||||:|||:|....|||
  Fly   601 DNQILIVIGETGSGKTTQITQ----YLGECGFTARGKIGCTQPRRVAAMSVAKRVAEEYGCRLGQ 661

Human   216 EVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIILDEAHERTLATDILMGVLKEVV 280
            ||||:||||||:|.:||:|||||||||||.:.:..|:.|.||:||||||||:.||:|.|:||..|
  Fly   662 EVGYTIRFEDCTSPETIIKYMTDGMLLRECLMEAELKSYSVIMLDEAHERTIHTDVLFGLLKTAV 726

Human   281 RQRSDLKVIVMSATLDAGKFQIYFDNCPLLTIPGRTHPVEIFYTPEPERDYLEAAIRTVIQIHMC 345
            ::|.:||:||.||||||.||..||...|:.||||||.|||:.||.|||.|||:|::.||:|||:
  Fly   727 QKRPELKLIVTSATLDAVKFSQYFFKAPIFTIPGRTFPVEVLYTKEPETDYLDASLITVMQIHL- 790

Human   346 EEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQN 410
            .|..||:|||||||||||.||:.:...:..|||:|.::.|:|:||.||.:.|.|||:|.|
  Fly   791 REPPGDILLFLTGQEEIDTACEILYERMKSLGPDVPELIILPVYSALPSEMQTRIFDPAP----- 850

Human   411 GAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGR 475
             |..||||::||||||||||||:.:|:||||.||||||.:..::||:||.||:|:|:||||||||
  Fly   851 -AGSRKVVIATNIAETSLTIDGIFYVVDPGFVKQKVYNSKTGMDSLVVTPISQAAAKQRAGRAGR 914

Human   476 TRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRAL 540
            |.|||.:|||||:||:.||.....|||.|:||.:.|||||.:||:||:||||||.|..|:|:.||
  Fly   915 TGPGKTYRLYTERAYRDEMLPTPVPEIQRTNLATTVLQLKTMGINDLLHFDFMDAPPVESLVMAL 979

Human   541 ELLNYLAALNDDGDLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSVPQCFVRPTE 605
            |.|:.|:||:|:|.||.||..||||||:|.|:||:|.|....||:|:|:|.:||||...|.||.:
  Fly   980 EQLHSLSALDDEGLLTRLGRRMAEFPLEPNLSKMLIMSVALQCSDEILTIVSMLSVQNVFYRPKD 1044

Human   606 AKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHESVQWCYDNFINYRSLMSADNVRQQLSRIMDR 670
            .:..||:.|.:|...:|||||||.||:::|.|..|..|||:||:..|:|..:.:||:||..||||
  Fly  1045 KQALADQKKAKFNQAEGDHLTLLAVYNSWKNNKFSNAWCYENFVQIRTLKRSQDVRKQLLGIMDR 1109

Human   671 FNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVL-DHKPEWV 734
            ..|...|....|    :.|:||:.:|:|...|..:....|.|:.|:|||.:|||:.| :.:||||
  Fly  1110 HKLDVVSAGKNS----VRIQKAICSGFFRNAAKKDPQEGYRTLVDSQVVYIHPSSALFNRQPEWV 1170

Human   735 LYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYDMSN 770
            :|:|.|.|||.|:|..|.|.|:|||:.||.::..|:
  Fly  1171 IYHELVQTTKEYMREVTTIDPKWLVEFAPSFFRFSD 1206

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX15	NP_001349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		26/133 (20%)
		HrpA	136..>763	CDD:441249	339/628 (54%)
		DEAH box	260..263		2/2 (100%)
pea	NP_610928.1	GH2-like_DHX8	7..74	CDD:409668
		S1_DHX8_helicase	285..363	CDD:240189
		HrpA	578..>1203	CDD:441249	342/639 (54%)