Protein Alignment DHX15 and CG3225

DIOPT Version :10

• Sequence 1: NP_001349.2
• Gene: DHX15 / 1665
• HGNCID: 2738
• Length: 795
• Species: Homo sapiens
• Sequence 2: NP_608860.1
• Gene: CG3225 / 33680
• FlyBaseID: FBgn0031631
• Length: 678
• Species: Drosophila melanogaster
• Alignment Length: 652
• Identity: 263/652 - (40%)
• Similarity: 407/652 - (62%)
• Gaps: 29/652 - (4%)

Human   130 ILKKRLQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPGPKRGVACTQPR 194
            ::::|.:||:.:|:|:....|.:||..:|||||||||:||:||:..|:.....|.   :..|:||
  Fly    40 LMEQRERLPIRQYRDQILYCLEKHQVVILVGETGSGKSTQVPQYLYEWGWHTKGL---IGITEPR 101

Human   195 RVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMNDPLLERYGVIIL 259
            ||:.:::|.|||.|...::|..|||.:||.:..|:.|.:|:||:|:||||.:.||||.:|||||:
  Fly   102 RVSTVTLANRVAQERGELVGDTVGYVVRFLESMSSCTKIKFMTEGILLREVLADPLLTQYGVIIV 166

Human   260 DEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYF------DNCPLLTIPGRTHP 318
            ||||||.:.||:::|:||:::|:||.||:|:.|||:||..|..:|      :....|:|.||.||
  Fly   167 DEAHERNMLTDMILGLLKKILRKRSSLKLIISSATIDASFFSEFFSWPGSGEVSVKLSIEGRMHP 231

Human   319 VEIFYTPEPERDYLEAAIRTVIQIHMCEEEEGDLLLFLTGQEEIDEACKRIKREVDDLGPEVGDI 383
            |..||..||..||::..:.||.::|. :|..||:|.|||||||:.||...::..:  ...|..::
  Fly   232 VSNFYLNEPCADYVKETVETVWKLHQ-KEPPGDILAFLTGQEEVLEALDLLREYI--ASSEQENL 293

Human   384 KIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNIAETSLTIDGVVFVIDPGFAKQKVYN 448
            |::|:|.::....|..:|..||    .|.  ||||::|||||||:||.|:|:|||.|:.|.|.||
  Fly   294 KVLPMYGSMSSTDQLSVFFTPP----KGT--RKVVLATNIAETSITIPGIVYVIDCGYVKVKWYN 352

Human   449 PRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEKAYKTEMQDNTYPEILRSNLGSVVLQ 513
            |:...:||::..:|||||.||||||||.||||.:||||:..|:. :.....||:.||.|...:||
  Fly   353 PKTCSDSLVIVPVSKASAIQRAGRAGRMRPGKVYRLYTKSDYEA-LAPRQPPEMRRSELSGAILQ 416

Human   514 LKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDGDLTE-LGSMMAEFPLDPQLAKMVIA 577
            ||.|||.:::.|||..||..:.|:.|||.|..|.|:::.|:||: :|.::||.|....|:||:..
  Fly   417 LKALGIGNILRFDFPSPPPAQNLLSALESLFALDAIDEQGNLTKPVGYLLAELPFSAMLSKMLYV 481

Human   578 SCDYNCSNEVLSITAMLSVPQCFVRPTE--AKKAADEAKMRFAHIDGDHLTLLNVYHAFKQNHES 640
            |....||.|:::|.|:|.|...|.||..  |:::...|..:|...:||.:|:||.|..|.:...:
  Fly   482 SGQMGCSEEIITIIALLQVQSIFSRPASAVAQQSGRIAHRKFEVAEGDFITMLNAYTGFVEEGMT 546

Human   641 VQWCYDNFINYRSLMSADNVRQQLSRI-MDRFNLPRRSTDFTSRDYYINIRKALVTGYFMQVAHL 704
            .::|...|:.||:|..|.::|:||..: ..::.:|    .|:.:.....:.|.:..|:|.|||:|
  Fly   547 KEFCGQYFLIYRNLKRAHSLREQLITVARKKYGIP----IFSCKGDVEKLCKCITAGFFTQVAYL 607

Human   705 ERTGHYLTVKDNQVVQLHPSTVLDHKP--EWVLYNEFVLTTKNYIRTCTDIKPEWLVKIAPQYYD 767
            ..:|.|..:.....:.:||::.|...|  ::|:|.|.:.|||.::...|.||.|||.::||.||.
  Fly   608 HHSGVYRQISSGTELAIHPNSTLYTLPQAQYVVYGELLQTTKLFMNYVTVIKREWLTELAPHYYQ 672

Human   768 MS 769
            .:
  Fly   673 QT 674

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX15	NP_001349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108
		HrpA	136..>763	CDD:441249	258/638 (40%)
		DEAH box	260..263		2/2 (100%)
CG3225	NP_608860.1	HrpA	38..>669	CDD:441249	260/645 (40%)