Protein Alignment DHX15 and CG32533

DIOPT Version :10

• Sequence 1: NP_001349.2
• Gene: DHX15 / 1665
• HGNCID: 2738
• Length: 795
• Species: Homo sapiens
• Sequence 2: NP_728244.1
• Gene: CG32533 / 32933
• FlyBaseID: FBgn0052533
• Length: 1139
• Species: Drosophila melanogaster
• Alignment Length: 708
• Identity: 211/708 - (29%)
• Similarity: 347/708 - (49%)
• Gaps: 69/708 - (9%)

Human    67 AMLISAG---LPPLKASHSAHSTHSAHSTHSTHSAHSTHAGHAGHTSLPQCINPFTNL------- 121
            ||:.|.|   |||..|.....|....|  .|.|.|....|......:..|..:.|.::
  Fly    65 AMMRSTGQPVLPPRLAEAELSSMQPYH--RSKHLALRLDADELLQEARDQMQSQFRHILLVYLDF 127

Human   122 PHTPRYYDILKKR---LQLPVWEYKDRFTDILVRHQSFVLVGETGSGKTTQIPQWCVEYMRSLPG 183
            ..|.::..|.|.|   ..||:..::....:.|...:..::.|:||.||:||:||:..::
  Fly   128 RQTEKFQRIRKLRQTQRNLPIARFRKDLREALDTSRVVIVAGDTGCGKSTQVPQYLYDF------ 186

Human   184 PKRGVACTQPRRVAAMSVAQRVADEMDVMLGQEVGYSIRFEDCSSAKTILKYMTDGMLLREAMND 248
            ..|.:|||||||:|.:|:.:|||.|:....|..|.:.||||...:..|.:.::|:|:|||:....
  Fly   187 GYRSIACTQPRRLACVSLCKRVAHELLDDYGSRVAFQIRFERSRTKLTNILFITEGLLLRQLAVA 251

Human   249 PLLERYGVIILDEAHERTLATDILMGVLKEVVRQRSDLKVIVMSATLDAGKFQIYF--DNCPLLT 311
            ..|::|..:||||.|||.|..|.|:||.|.::|.|..||:|:||||::...|..||  :...|:.
  Fly   252 ANLDQYDALILDEIHERNLFGDFLLGVTKCLLRARPQLKLILMSATINVELFHGYFGEEGARLVQ 316

Human   312 IPGRTHPVEIFYTPEP--------------ERDYLEAA----IRTVIQIHMCEEEEGDLLLFLTG 358
            :|||..|:::.|.|.|              :|:.::.|    :.::|.......|.||:|:|::|
  Fly   317 VPGRLFPIKLRYLPPPALELKAGQATSKRSQRNRIDPAPFVQVLSLIDQQYPTSERGDVLIFVSG 381

Human   359 QEEIDEACKRIKREVDDLGPEVGDIKIIPLYSTLPPQQQQRIFEPPPPKKQNGAIGRKVVVSTNI 423
            ..||:.    :...|.:...|.....::||:|......|.::|:..|...      ||.:|||||
  Fly   382 VNEIES----VVEAVHEYATEQTHWLVLPLHSGQAIADQSKVFDYAPEGM------RKCIVSTNI 436

Human   424 AETSLTIDGVVFVIDPGFAKQKVYNPRIRVESLLVTAISKASAQQRAGRAGRTRPGKCFRLYTEK 488
            ||||||:|||.||:|.|..|:..::...:.:.|....:||:||.||.||||||.||.||||||.:
  Fly   437 AETSLTVDGVRFVVDSGKVKEMNFDATCKGQRLKEFWVSKSSADQRKGRAGRTGPGVCFRLYTAE 501

Human   489 AYKTEMQDNTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLAALNDDG 553
            .|.. .:....|||.|..|.:::||:..:|:.|:..|.|::.|..|.:.:.:..|....||:.:.
  Fly   502 QYNA-FEAYPTPEIYRVPLDTMLLQMVSMGLPDVRAFPFIEAPETERIEQTILALKQHCALSVEE 565

Human   554 DLTELGSMMAEFPLDPQLAKMVIASCDYNCSNEVLSITAMLSV--PQCFVRPTEAKKAADEAKMR 616
            .:|.||..:|..|::..:.||::....:....::|::.|||||  |......|:.:...:...:.
  Fly   566 KITPLGRSLANLPVELSIGKMLLMGSVFPEVEQLLTLAAMLSVQNPLTNRAHTDQRCVRERESLE 630

Human   617 FAHIDGDHLTLLNVYHAFKQ----NHESVQWCYDNFINYRSLMSADNVRQQLSRIMDRFNLPRRS 677
            ..|  ||..||:.:|:.:.|    ...:.|||....|..:.......:|||..||::...:...|
  Fly   631 SDH--GDLFTLVRLYNVWVQLKMRRDGTRQWCRRLGIEEQRFYEVTKLRQQFQRILESCGMVVAS 693

Human   678 ---TDFTSRDYYINIRKALVTGYFMQVAHLERTGHYLTVKDNQVVQLHPSTVLDHKPE 732
               :..||.:      :|...|...|:..::|...:...:..::::.....|.:.:.|
  Fly   694 DSDSQLTSAE------RATRHGELRQLKAMKRRQRFEQPRQRKLLKQSAGRVAEDEEE 745

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DHX15	NP_001349.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..108		14/43 (33%)
		HrpA	136..>763	CDD:441249	191/626 (31%)
		DEAH box	260..263		2/2 (100%)
CG32533	NP_728244.1	HrpA	145..>619	CDD:441249	165/490 (34%)
		OB_NTP_bind	792..897	CDD:400182