DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Serpina3c and Spn42Dd

DIOPT Version :9

Sequence 1:	XP_011242304.1	Gene:	Serpina3c / 16625	MGIID:	102848	Length:	436	Species:	Mus musculus
Sequence 2:	NP_001163067.1	Gene:	Spn42Dd / 49808	FlyBaseID:	FBgn0028988	Length:	372	Species:	Drosophila melanogaster

Alignment Length:	383	Identity:	126/383 - (32%)
Similarity:	189/383 - (49%)	Gaps:	31/383 - (8%)

- Green bases have known domain annotations that are detailed below.

Mouse    64 LTLASINTDFAFSLYKKLALKNPDTNIVFSPLSISAALAIVSLGAKGNTLEEILEGLNFNLTETP 128
            |.:.|:....:..:|:.|:..:.:.|:|.||:||...|::|.:||:|:|.:|:...|... :|..
  Fly     8 LWVTSVACQTSKEIYQLLSKSHTNQNLVVSPVSIETILSMVFMGAEGSTAKELQSALGLP-SEDK 71

Mouse   129 EADIHQGFGHLLQRLSHPGEQVQISTGSALFVEKHLQILAEFQEKARALYQAEAFTADFQQPLEA 193
            || :...:|.||..|....|...:...:.::|.....:...:....|..:::||.:........|
  Fly    72 EA-VAARYGALLNDLQGQEEGPILKLANRIYVNDQYSLNQNYNLAVREPFKSEAESISLTNGPVA 135

Mouse   194 TKLINDYVSNQTQRKIKGLI--SDLDTDTLMVLVNYIYFKGKWKMPFNPRDTFESEFYLDVKRSV 256
            .:.||.:|.:||..||||:|  ..:.:|...:|||.|||||:|:..|:|..|..|.|.:...:||
  Fly   136 AERINQWVLDQTSGKIKGMIDPGSMTSDVKALLVNAIYFKGQWESKFDPAKTRASTFQVTANKSV 200

Mouse   257 KVPMM-KIKTLTTPYFRDEELSCTVVELKY-KGNASALFILPDQGRMQQVEASLQPETLRKWKNS 319
            .|.|| ::.|....||||  |...|:||.| ..|.|....||     ::||.....|  .|....
  Fly   201 PVQMMAQMGTFRANYFRD--LDAQVIELPYLNSNLSMTIFLP-----REVEGLSALE--EKIVGF 256

Mouse   320 LRPRKMGELY--LPKFSISTDYSLKNILPELGIKEIFSKQADLSGI----TGTKDLIVSQMVHKA 378
            .||....|:|  ||||.|.....||..|.:|||:|:|:.::||||:    :|.|   |||:.|||
  Fly   257 ARPLVAKEVYLKLPKFKIEFRDELKETLEKLGIRELFTDKSDLSGLFADKSGGK---VSQVSHKA 318

Mouse   379 VLDVAETGTEGVAATGVNFRILSR---RTSLWFNRTFLMVISHTDVQTTLFIAKITHP 433
            .|:|.|.|.|...||.|  .:.:|   .|.|..:..|..||  .|..|..|..::..|
  Fly   319 FLEVNEEGAEAAGATSV--AVTNRAGFSTFLMADHPFAFVI--RDANTIYFQGRVVSP 372

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Serpina3c	XP_011242304.1	serpinA3_A1AC	56..434	CDD:381019	126/383 (33%)
Spn42Dd	NP_001163067.1	SERPIN	16..369	CDD:238101	123/370 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11461
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X28
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.010