Protein Alignment Kif5a and Khc

DIOPT Version :10

• Sequence 1: NP_032473.2
• Gene: Kif5a / 16572
• MGIID: 109564
• Length: 1027
• Species: Mus musculus
• Sequence 2: NP_476590.1
• Gene: Khc / 36810
• FlyBaseID: FBgn0001308
• Length: 975
• Species: Drosophila melanogaster
• Alignment Length: 140
• Identity: 32/140 - (22%)
• Similarity: 54/140 - (38%)
• Gaps: 31/140 - (22%)

Mouse   131 STTHQSEQQLRGELLHVYHQIVSMLTQASIK---------RIFEHRKNYDLRRLLFGSERVLDSL 186
            |...|.:||       .:|.|.|..|::...         ...:.|.....|   |..|:.||.|
  Fly   149 SLEQQQQQQ-------QHHTINSQWTESCSSGSQHQFQPLTTAQRRSTASAR---FSGEQELDEL 203

Mouse   187 LD--VMDF---DPSFMLSAVQCLPLPSSSRDILSNILQKSITPNLVFSFLIAQNRLVSIVQEKTV 246
            :|  :.||   |||.:........|.|      .|.||......|: :.:|.:..:.|:.::.|:
  Fly   204 VDQKLNDFLQHDPSVVYGKHVANKLRS------LNELQNKFAQKLI-NDIIFEAEMGSLSRDCTL 261

Mouse   247 AEDTRLKPSD 256
            ...|.::|::
  Fly   262 EGLTGVEPNN 271

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif5a	NP_032473.2	KISc_KHC_KIF5	7..327	CDD:276820	32/140 (23%)
		Microtubule-binding	174..315		22/88 (25%)
		Necessary for interaction with ZFYVE27. /evidence=ECO:0000269|PubMed:21976701	271..361
		Interaction with BICD2. /evidence=ECO:0000250|UniProtKB:Q12840	353..1027
		PRK03918	<409..920	CDD:235175
		Khc_CBD_cc	832..901	CDD:467880
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	906..937
		Globular	907..1027
Khc	NP_476590.1	KISc_KHC_KIF5	10..333	CDD:276820	32/140 (23%)
		Smc	<341..>807	CDD:440809
		Khc_CBD_cc	856..925	CDD:467880