Protein Alignment Kif3a and CG14535

DIOPT Version :10

• Sequence 1: XP_006532388.1
• Gene: Kif3a / 16568
• MGIID: 107689
• Length: 725
• Species: Mus musculus
• Sequence 2: NP_609156.1
• Gene: CG14535 / 34073
• FlyBaseID: FBgn0031955
• Length: 1131
• Species: Drosophila melanogaster
• Alignment Length: 597
• Identity: 139/597 - (23%)
• Similarity: 235/597 - (39%)
• Gaps: 117/597 - (19%)

Mouse    15 VKVVVRCRPLNEREKSMCYRQAVSVDEMRGTITVHKTDSSNEP-------------PKTFTFDTV 66
            |||::|... .:|.........:::|:.:..:|:....::..|             ||.|.||.:
  Fly    45 VKVMLRVAD-RDRNSGGTEPDFMALDKKKRQVTLTDPRTACPPPQAAQERAPMVAAPKMFAFDNL 108

Mouse    67 FGPESKQLDVYNLTARPIIDSVLEGYNGTIFAYGQTGTGKTFTM---------EGVRAVPGLR-- 120
            |..|.||.||.......:|.:||||.:|.:.|.|...||:..|:         .|..:..|:.
  Fly   109 FTGEDKQSDVCASALSEVIPAVLEGSDGCLLAMGYPATGQAQTVLGELGGGSGSGSASGSGVACS 173

Mouse   121 -GVIPNSFAHIFGHI--AKAEGDTRFLVRVSYLEIYNEEVRDLLGKDQ--TQRLEVKERPDVGVY 180
             |..|.:.|.::..|  .:.:...||.||||.:.: :....|.|.:|.  :...|..:.|  |:|
  Fly   174 LGAAPCAIAWLYKGIQERRQKSGARFSVRVSAVGV-SATKPDALSQDLLISHAAESDDSP--GIY 235

Mouse   181 IKD--LSAYVVNNADDMDRI-----MTLGHKNRSVGATNMNEHSS----RSHAIFTITI---ECS 231
            ::|  |.......|...:|.     ..|..:.:|.|:|.......    .|..|||:.:   ..|
  Fly   236 LRDDFLGGPTELRAPTAERAALFLDSALAGRLKSSGSTASGSSGCAAPLESALIFTLHVYQYSLS 300

Mouse   232 EK-GVDGNMHVRMGKLHLVDLAGSERQAKTGATGQRLKEATKINLSLSTLGNVISALVDGKSTHV 295
            .| ||.|.    ..:||::||.|...  :.|            .|.||.:||::.|::.|: .|.
  Fly   301 RKGGVAGG----RSRLHIIDLGGCAN--RNG------------GLPLSGIGNILLAILSGQ-RHP 346

Mouse   296 PYRNSKLTRLLQDSLGG-NSKTMMCANIGPADYNYDETISTLRYANRAKNIKNKARINEDPKDAL 359
            |:::..||.||:|.|.. .....:.|::.| :.:|.:.:||::.|:|...::.:......|....
  Fly   347 PHKDHPLTPLLKDCLAPITCHVAIVAHVRP-EQSYQDALSTIQIASRIHRLRRRKHRVPMPLAVG 410

Mouse   360 LRQFQKEIEELKKKLEEGEEVSGSDIS-------GSEEDDEEGE----------LGED-GEKKKK 406
            |.|   .:.........|.:.|.|:||       |..:|..:||          .|:: |...|.
  Fly   411 LAQ---GLGGNGSSAGSGADPSSSEISADTVIYMGPNDDATDGEHPPVYLPSLTAGDNRGVMSKA 472

Mouse   407 RRGSS-----SSSSSDSTCSVIEKPLDE-----------FLPHQAGKKKVSPDKMVEMQAKIDEE 455
            .:||.     |.|:|:|...:.:....|           .|..|||....|...:...|.:|
  Fly   473 LKGSGLEKPPSKSASNSPMMMKKAMAAEKAKKLPGSHTGSLKRQAGAGACSSPMIPHEQPQI--- 534

Mouse   456 RKALETKLDMEEEERNKARAELERREKDLLKAQQEHQSLLEKLSALEKKV-----IVGGVDLLAK 515
             :|:.:.:.:.....:|.......:...:.:|..  .:.||:|.|..:|:     |.|.....||
  Fly   535 -QAMGSPIPIPRHMVSKGSMVPSPKGSPMRRAHP--GAALEQLEAGMRKITEEQWIDGPRVSRAK 596

Mouse   516 AEEQEKLLEESN 527
            ..|...|:.|.|
  Fly   597 VAEARHLMREVN 608

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kif3a	XP_006532388.1	KISc_KIF3	13..345	CDD:276822	94/374 (25%)
		Smc	<450..>614	CDD:440809	17/83 (20%)
CG14535	NP_609156.1	Motor_domain	44..394	CDD:473979	94/372 (25%)