Protein Alignment Kdr and Cad96Ca

DIOPT Version :9

• Sequence 1: NP_034742.2
• Gene: Kdr / 16542
• MGIID: 96683
• Length: 1345
• Species: Mus musculus
• Sequence 2: NP_651349.1
• Gene: Cad96Ca / 43026
• FlyBaseID: FBgn0022800
• Length: 773
• Species: Drosophila melanogaster
• Alignment Length: 365
• Identity: 137/365 - (37%)
• Similarity: 197/365 - (53%)
• Gaps: 67/365 - (18%)

Mouse   812 DERCERLPYDASKWEFPRDRLKLGKPLGRGAFGQVIEADAFGIDKTATCKTVAVKMLKEGATHSE 876
            :..|:|       |||||.|||....||.||||||...:|..|:......|||||.|||.||..:
  Fly   457 EANCDR-------WEFPRYRLKFFNILGEGAFGQVWRCEATNINGNEGITTVAVKTLKESATEVD 514

Mouse   877 HRALMSELKILIHIGHHLNVVNLLGACTKPGGPLMVIVEFCKFGNLSTYLRGKRNEFVPYKSKGA 941
            .:.|:|||:::..:..|:|||:|||.||.. .|..||:|:...|.|.||||..|.|
  Fly   515 RKDLLSELEVMKSLEPHINVVHLLGCCTDK-DPTFVILEYVNRGKLQTYLRSSRAE--------- 569

Mouse   942 RFRQGKDYVGELSVDLKRRLDSITSSQSSASSGFVEEKSLSDVEEEEASEELYKDFLTLEHLICY 1006
                 :.|                        |....||               :.||...|..:
  Fly   570 -----RHY------------------------GNTHGKS---------------NVLTSCDLTSF 590

Mouse  1007 SFQVAKGMEFLASRKCIHRDLAARNILLSEKNVVKICDFGLARDIYKDPDYVRKGDARLPLKWMA 1071
            .:||||||::|.||..|||||||||||:::.:..|:.|||.|||:.....|.||.:.:||::|||
  Fly   591 MYQVAKGMDYLTSRGIIHRDLAARNILITDDHTCKVADFGFARDVITSKIYERKSEGKLPIRWMA 655

Mouse  1072 PETIFDRVYTIQSDVWSFGVLLWEIFSLGASPYPGVKIDEEFCRRLKEGTRMRAPDYTTPEMYQT 1136
            .|:::|.:::::||:||||:|:|||.:||::||||:.. .:..|::::|.|:..|::...|:|..
  Fly   656 TESLYDNIFSVKSDIWSFGILMWEIVTLGSTPYPGISA-ADVMRKVRDGYRLEKPEHCRRELYNI 719

Mouse  1137 MLDCWHEDPNQRPSFSELVEHLGNLLQANAQQDGKDYIVL 1176
            |..||..||.:||.|:|:::.|..||...     .|||.|
  Fly   720 MYYCWSHDPQERPLFAEIIQMLDKLLHTE-----MDYIEL 754

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kdr	NP_034742.2	Ig_3	31..105	CDD:404760
		Ig	226..327	CDD:416386
		Ig strand A	226..230	CDD:409353
		Ig strand A'	236..240	CDD:409353
		Ig strand B	242..251	CDD:409353
		Ig strand C	258..263	CDD:409353
		Ig strand C'	266..268	CDD:409353
		Ig strand D	272..280	CDD:409353
		Ig strand E	288..296	CDD:409353
		Ig strand F	306..312	CDD:409353
		Ig strand G	317..323	CDD:409353
		Ig	331..419	CDD:416386
		Ig strand A	331..334	CDD:409353
		Ig strand A'	341..345	CDD:409353
		Ig strand B	347..358	CDD:409353
		Ig strand C	362..368	CDD:409353
		Ig strand C'	370..373	CDD:409353
		Ig strand D	378..381	CDD:409353
		Ig strand E	383..388	CDD:409353
		Ig strand F	396..404	CDD:409353
		Ig strand G	410..419	CDD:409353
		Ig_3	549..643	CDD:404760
		I-set	665..742	CDD:400151
		Ig strand B	682..686	CDD:409353
		Ig strand C	695..699	CDD:409353
		Ig strand E	718..722	CDD:409353
		Ig strand F	732..737	CDD:409353
		VEGFR-2_TMD	757..791	CDD:375470
		PTKc_VEGFR2	824..1165	CDD:270681	131/340 (39%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1272..1316
Cad96Ca	NP_651349.1	Cadherin_repeat	65..164	CDD:206637
		STYKc	470..741	CDD:214568	122/325 (38%)
		PTKc	474..742	CDD:270623	120/322 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG0200
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S4350
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.760