Protein Alignment Kcnj5 and Irk3

DIOPT Version :9

• Sequence 1: XP_017168642.1
• Gene: Kcnj5 / 16521
• MGIID: 104755
• Length: 468
• Species: Mus musculus
• Sequence 2: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Alignment Length: 324
• Identity: 107/324 - (33%)
• Similarity: 188/324 - (58%)
• Gaps: 14/324 - (4%)

Mouse    96 KKPRQRYMEKTGKCNVHHGNVQE-TYRYLSDLFTTLVDLKWRFNLLVFTMVYTITWLFFGFIWWL 159
            ::...|.|||.||.||....:.| ::||:.||.|||::|:|::.|.:|...|.::||.|..:.::
  Fly   112 RRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLLFAALCYV 176

Mouse   160 IAYVRGD--LDHVGDQ---EWI-PCVENLSGFVSAFLFSIETETTIGYGFRVITEKCPEGIILLL 218
            :||..||  .|.|..:   |.: ||:..:..:|:..::|:||:||:|:|.:..:|:|||.|.|.:
  Fly   177 VAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECPETIFLFV 241

Mouse   219 VQAILGSIVNAFMVGCMFVKISQPKKRAETLMFSNNAVISMRDEKLCLMFRVGDLRNSHIVEASI 283
            :|.:..:::...||..::.|.::|.::...|.||:.|||..||.:|||:|||.|.|....:|:.|
  Fly   242 MQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQQSIESKI 306

Mouse   284 RAKLIKSRQTKEGEFIPLNQTDINVGFDTGDDRLFLVSPLIISHEINEKSPFWEMSRAQL-EQEE 347
            |..:|..::|:|||.|   ::.:.:..: |:....::.|.::.|.|:|.||..:.:.|:| ...:
  Fly   307 RVYIIVDKRTREGETI---KSHVELKLE-GNGEQIILWPDVVCHVIDETSPLSQFTTAKLFNAAQ 367

Mouse   348 FEVVVILEGMVEATGMTCQARSSYMDTEVLWGHRFTPVL--TLEKGFYEVDYNTFHDTYETNTP 409
            ||:.|.:.|...||....:|::||:..|:.||.||..::  ..:...|.|||..|:.|...:.|
  Fly   368 FELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRTISVDMP 431

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcnj5	XP_017168642.1	IRK	103..242	CDD:366415	50/145 (34%)
		IRK_C	249..420	CDD:375232	55/164 (34%)
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	106/317 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020