Protein Alignment Kcnj12 and Irk3

DIOPT Version :9

• Sequence 1: NP_034733.4
• Gene: Kcnj12 / 16515
• MGIID: 108495
• Length: 529
• Species: Mus musculus
• Sequence 2: NP_001137835.2
• Gene: Irk3 / 35131
• FlyBaseID: FBgn0032706
• Length: 446
• Species: Drosophila melanogaster
• Alignment Length: 463
• Identity: 148/463 - (31%)
• Similarity: 234/463 - (50%)
• Gaps: 66/463 - (14%)

Mouse    21 AASPRRLSTPTLATFPWK----AQEP---GAEMSSQNA----PRVP---QPRQPSASWPRQKQHP 71
            ||:...|:.....:.|.|    .|:|   .:|..:.||    |..|   :.|:..|:....:...
  Fly    10 AAATDSLTMHRSTSMPVKPKPLEQKPLLRSSEKETVNASDYYPESPGFVRRRRSKAAGDHLETRS 74

Mouse    72 PLQPQASAKQAHEVPPPGVSL--GAGQGPPDPGMTAASRANPYSIVSSEEDGLHLVTMSGANGFG 134
            ...|..|...||:.....:.|  ..|.||.                :|..|||
  Fly    75 EQNPTFSFPYAHDWAGSTIELTPDLGSGPR----------------TSSSDGL------------ 111

Mouse   135 NGKVHTRRRCRNRFVKKNGQCNIEFANMDEKSQRYLADMFTTCVDIRWRYMLLIFSLAFLASWLL 199
                   ||..||.::|||:.|:.|..:.|||.||:.|:.||.:::.|:|||.:|..::..||||
  Fly   112 -------RRSLNRVMEKNGKENVVFRRIPEKSWRYMRDLVTTLMELEWKYMLTLFLGSYFLSWLL 169

Mouse   200 FGIIFWVIAVAHGD--LEPAEGR----GRTPCVLQVHGFMAAFLFSIETQTTIGYGLRCVTEECP 258
            |..:.:|:|.:|||  .:|..|:    |..||:..||.::|..::|:|||||:|:|.:..:||||
  Fly   170 FAALCYVVAYSHGDFIFDPVSGKRMGEGVDPCIYGVHSWVAMIIYSVETQTTLGFGEKYASEECP 234

Mouse   259 VAVFMVVAQSIVGCIIDSFMIGAIMAKMARPKKRAQTLLFSHNAVVALRDGKLCLMWRVGNLRKS 323
            ..:|:.|.|.:...:|:..|:..|.||.|||.::...|.||..||:..|||:|||::||.:.|:.
  Fly   235 ETIFLFVMQMLSAALIEGCMVSVIYAKTARPARQLTKLKFSDKAVICYRDGRLCLLFRVCDPREQ 299

Mouse   324 HIVEAHVRAQLIKPRVTEEGEYIPLDQIDIDVGFDKGLDRIFLVSPITILHEIDEASPLFGISRQ 388
            ..:|:.:|..:|..:.|.|||.|. ..:::.:   :|.....::.|..:.|.|||.|||...:..
  Fly   300 QSIESKIRVYIIVDKRTREGETIK-SHVELKL---EGNGEQIILWPDVVCHVIDETSPLSQFTTA 360

Mouse   389 DL-ETDDFEIVVILEGMVEATAMTTQARSSYLANEILWGHRFEPVL-FEEKNQ-YKIDYSHFHKT 450
            .| ....||:.|.:.|...|||..|:|::|||..||.||.||..:: ::.:|: |.:||.:|::|
  Fly   361 KLFNAAQFELYVSIVGTSPATAQMTEAKTSYLPREIFWGQRFVNIIHYDAQNERYIVDYENFNRT 425

Mouse   451 YEV--PST 456
            ..|  |.|
  Fly   426 ISVDMPMT 433

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcnj12	NP_034733.4	PRK07764	<9..111	CDD:236090	22/105 (21%)
		IRK_N	104..148	CDD:369890	7/43 (16%)
		IRK	149..289	CDD:366415	57/145 (39%)
		IRK_C	296..468	CDD:375232	59/166 (36%)
Irk3	NP_001137835.2	Ion_trans_2	119..432	CDD:304432	116/316 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D289862at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR11767
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	3.020