Protein Alignment Kcna7 and Shawl

DIOPT Version :9

• Sequence 1: NP_034726.2
• Gene: Kcna7 / 16495
• MGIID: 96664
• Length: 489
• Species: Mus musculus
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 572
• Identity: 185/572 - (32%)
• Similarity: 252/572 - (44%)
• Gaps: 171/572 - (29%)

Mouse    46 RLVLNVAGLRFETRARTLGRFPDTLLGDPVRRSRFYDGARREYFFDRHRPSFDAVLYYYQSGGRL 110
            |::|||:|:|:||...||.:.|.|.|.........||....|||||||...|..:|.||::|
  Fly     6 RIILNVSGIRYETYKATLKKIPATRLSRLTEALANYDPVLNEYFFDRHPGVFTQILNYYRTG--- 67

Mouse   111 RRPAHVPLDV----FLEEVSFYGLGA---------------------AALARLR-EDEGCAVPPE 149
              ..|.|.||    |.||:.|:||.:                     |.|.:|. |:|   .|.|
  Fly    68 --KLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLAILDKLDIENE---KPTE 127

Mouse   150 RPLPR----------------RAFARQLWLLFEFPESSQAARVLAVVSVLVILVSIVVFCLETLP 198
            ..:.|                :....::|.:|:.|.||..|:::|.:||..|.||::.|||:|.|
  Fly   128 EQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFIFVSVISFCLKTHP 192

Mouse   199 DFR-------DDRDDPG------------------------LAPVAAATGPFLARLNGSSPMPG- 231
            .||       .|...||                        :.|.:.:.||.....|.:|...|
  Fly   193 GFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPTFRVTNYTSYSSGN 257

Mouse   232 ------APP--------------------------------------------RQPFNDPFFVVE 246
                  |.|                                            .|| ::.||.||
  Fly   258 FTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIETYGQP-HEAFFYVE 321

Mouse   247 TLCICWFSFELLVRLVACPSKAVFFKNVMNLIDFVAILPYFVALGTELARQRGVGQPAMSLAILR 311
            .:|..||..|:::||:..|:...|.|:.:|:|||.|.|.::..:...:....|         :|.
  Fly   322 LVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYTDVMQRMGEYTG---------LLE 377

Mouse   312 VIRLVRVFRIFKLSRHSKGLQILGQTLRASMRELGLLIFFLFIGVVLFSSAVYFAE--VDRVDTH 374
            ...:||:.|:|||:|||.||:||..|.:||.:||.||:|||.:|:|.|:|..|:||  .|..|..
  Fly   378 AFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYYAEKLQDNPDNQ 442

Mouse   375 FTSIPESFWWAVVTMTTVGYGDMAPVTVGGKIVGSLCAIAGVLTISLPVPVIVSNFSYFY----- 434
            |.|||...|||:||||||||||:||.|..|..||:|||:||||||:|||||||||||.||
  Fly   443 FKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVSNFSMFYSHTQA 507

Mouse   435 -------------------HRETEGEEAGMYSHV-DTQPCGTLEGKANGGLV 466
                               .||......|..:.: .|.|.|  .|...||:|
  Fly   508 RSKLPKKRRRVLPVEQPRRKREPTAPHRGRTNAIKQTPPTG--PGLVAGGVV 557

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Kcna7	NP_034726.2	BTB_2	47..137	CDD:280393	38/114 (33%)
		BTB	47..130	CDD:197585	34/86 (40%)
		Ion_trans	228..437	CDD:278921	103/285 (36%)
		Ion_trans_2	352..431	CDD:285168	51/80 (64%)
		Selectivity filter. /evidence=ECO:0000250	391..396		4/4 (100%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	36/96 (38%)
		BTB_2	7..97	CDD:280393	36/94 (38%)
		Ion_trans	307..506	CDD:278921	100/208 (48%)
		Ion_trans_2	<449..499	CDD:285168	37/49 (76%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D818306at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.820