Protein Alignment AKR1C1 and CG2767

DIOPT Version :9

• Sequence 1: NP_001344.2
• Gene: AKR1C1 / 1645
• HGNCID: 384
• Length: 323
• Species: Homo sapiens
• Sequence 2: NP_649757.1
• Gene: CG2767 / 40946
• FlyBaseID: FBgn0037537
• Length: 329
• Species: Drosophila melanogaster
• Alignment Length: 333
• Identity: 127/333 - (38%)
• Similarity: 202/333 - (60%)
• Gaps: 17/333 - (5%)

Human     1 MDSKYQCVKLNDGHFMPVLGFGTYAPAEVPKSKALEATKLAIEAGFRHIDSAHLYNNEEQVGLAI 65
            :::|:  :..|:|..|||:|.||:..::.....|::|   |:|||:||||:|.:|.||:.:|..:
  Fly     2 VNTKF--LTFNNGEKMPVIGIGTWQASDEEIETAIDA---ALEAGYRHIDTAPVYGNEKAIGRVL 61

Human    66 RSKIADGSVKREDIFYTSKLWCNSHRPELVRPALERSLKNLQLDYVDLYLIHFPVSVKPGEEVIP 130
            :..:..|.||||::|..:|:...|:||..|.|.:::||::||||||||||:|.|.::...|:...
  Fly    62 KRWLDAGKVKREELFIVTKVPPVSNRPHEVEPTIKKSLEDLQLDYVDLYLVHTPFTININEDGSF 126

Human   131 K-DENGKILFD-TVDLCATWEAVEKCKDAGLAKSIGVSNFNRRQLEMILNKPGLKYKPVCNQVEC 193
            | |:.|.:..| |.:..|.|.|:|...:.||.||||||||::.|:..:|.  ..|.:|..||:|.
  Fly   127 KLDKEGLMEVDVTTNHAAIWVAMEALVEKGLTKSIGVSNFSKDQVARLLK--NCKIRPANNQIEH 189

Human   194 HPYFNQRKLLDFCKSKDIVLVAYSALGS-----HREEPWVDPNSPVLLEDPVLCALAKKHKRTPA 253
            |.|..||.|:|||||::|.:.|||.|||     ......:..:.|.|::.|.:..:|..|.:|||
  Fly   190 HVYLQQRDLVDFCKSENITVTAYSPLGSKGIAKFNAGAGIVRDLPDLMDIPEVKEIAASHGKTPA 254

Human   254 LIALRYQLQRGVVVLAKSYNEQRIRQNVQVFEFQLTSEEMKAIDGLNRNVRYLTLDIFAG---PP 315
            .:.||:.:..||..:.||.|..|::||:.||:|:||:||:..:..|::|:|......|.|   .|
  Fly   255 QVLLRWIIDTGVSAIPKSTNPARLKQNLDVFDFELTAEEVAKLSSLDQNIRICDFAFFHGVERHP 319

Human   316 NYPFSDEY 323
            .:.|.::|
  Fly   320 EFTFKNQY 327

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
AKR1C1	NP_001344.2	AKR_AKR1C1-35	6..308	CDD:381334	121/308 (39%)
CG2767	NP_649757.1	ARA1	5..302	CDD:223729	120/303 (40%)
		Tas	10..297	CDD:223739	118/291 (41%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG53635
OrthoDB	1	1.010	-	-		D1016440at2759
OrthoFinder	1	1.000	-	-		FOG0000042
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100072
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X51
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	6	5.830