DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment DCX and CaMKI

DIOPT Version :9

Sequence 1:	NP_000546.2	Gene:	DCX / 1641	HGNCID:	2714	Length:	441	Species:	Homo sapiens
Sequence 2:	NP_524622.1	Gene:	CaMKI / 43792	FlyBaseID:	FBgn0016126	Length:	405	Species:	Drosophila melanogaster

Alignment Length:	148	Identity:	28/148 - (18%)
Similarity:	54/148 - (36%)	Gaps:	45/148 - (30%)

- Green bases have known domain annotations that are detailed below.

Human    17 LPKLEMLTLGSSFCSLQG----------EFCQAMD--SFTTVSHVGMC------EETDASF--NV 61
            |.|:|...:.::.|...|          .:.:|:|  |...:|::.:|      :|.||:.  .:
  Fly   192 LSKMEDSGIMATACGTPGYVAPEVLAQKPYGKAVDVWSIGVISYILLCGYPPFYDENDANLFAQI 256

Human    62 FSPKFQFDRSH----------------CQSLRFHQNMELDFGH--FDERDKTSRNMRGSRMNGLP 108
            ....|:||..:                |.::......:...||  ....:.:|||:.|:....|.
  Fly   257 LKGDFEFDSPYWDEISESAKHFIKNLMCVTVEKRYTCKQALGHAWISGNEASSRNIHGTVSEQLK 321

Human   109 SPTHSAHCSFYRTRTLQA 126
            .       :|.::|..||
  Fly   322 K-------NFAKSRWKQA 332

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
DCX	NP_000546.2	DCX	129..219	CDD:214711
DCX	NP_000546.2	DCX	256..344	CDD:214711
CaMKI	NP_524622.1	STKc_CaMKI	27..301	CDD:270985	19/108 (18%)
CaMKI	NP_524622.1	S_TKc	31..302	CDD:214567	19/109 (17%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D330091at2759
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.920