Sequence 1: | NP_001316985.1 | Gene: | Insr / 16337 | MGIID: | 96575 | Length: | 1384 | Species: | Mus musculus |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_001287331.1 | Gene: | Sdr / 41809 | FlyBaseID: | FBgn0038279 | Length: | 868 | Species: | Drosophila melanogaster |
Alignment Length: | 946 | Identity: | 263/946 - (27%) |
---|---|---|---|
Similarity: | 411/946 - (43%) | Gaps: | 217/946 - (22%) |
- Green bases have known domain annotations that are detailed below.
Mouse 11 AVPLLVAVAALLVGTAGHLYPGE----VCPGMDIRNNLTRLHELENCSVIEGHLQILLMFKTRPE 71
Mouse 72 DFRDLS--------FPKLIMITDYLLLFRVYGLESLKDLFPNLTVIRGSRLFFN-YALVIFEMVH 127
Mouse 128 LKELGLYNLMNITRGSVRIEKNNELCYLATIDWSRILDSVEDNYIVL--NKDDNEECGDVCPGTA 190
Mouse 191 KGKTNCPATVINGQFV----ERCWTHSHCQ--------KVCPTICKSHGCTAEGLCCHKECLGNC 243
Mouse 244 SEPDDPTKCVACRNFYLDGQCVETCPPPYYHFQDWRCVNFSFCQDLHFKCRNSRKPGCHQYVIHN 308
Mouse 309 NKCIPECPSGYTMNSSNLMCTPCLGPCPKVCQILEGEKTIDSVTSAQELRGCTVINGSLII---N 370
Mouse 371 IRGGNNLAAELEANLGLIEEISGFLKIRRSYALVSLSFFRKLHLIRGETLEIGNYSFYALDNQNL 435
Mouse 436 RQLWDWSKHNLTITQGKLFFHYNPKLCLSEIHKMEEVSGTKGRQERNDIALKTNGDQASCEN--- 497
Mouse 498 ------ELLKFSFIRTSFDKILLRWEPYWPPDFRDLLGFMLFYKEAPYQNVTEFDGQDACGSNSW 556
Mouse 557 TVVDIDPPQRSNDPKSQTPSHPGWLMRGLKPWTQYAIFVKTLVTFSDERRTYGAKSDIIYVQTDA 621
Mouse 622 TNPSVPLDPISVSNSSSQIILKWKPPSDPNGNITHYLVYWERQAEDSELFELDYCLKGLKLPSRT 686
Mouse 687 WSPPFESDDSQKHNQSEYDDSASECCSC---------PKTDSQILKELEESSFRK---TFEDYLH 739
Mouse 740 NVVFVPRK-----------------TSSGNGAEDSRP---------------------------- 759
Mouse 760 -SRKRRSLEEVGNVTATTL-TLPDFPNVSSTIVPTSQEEHRPFEKVVNKESL---VISGLRHF-- 817
Mouse 818 -------TGYRIELQACNQDSPDERCSVAAYVSART 846 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
Insr | NP_001316985.1 | Recep_L_domain | 52..164 | CDD:279382 | 44/120 (37%) |
Furin-like | 179..337 | CDD:279142 | 39/169 (23%) | ||
FU | 234..281 | CDD:238021 | 12/46 (26%) | ||
Recep_L_domain | 359..472 | CDD:279382 | 45/115 (39%) | ||
FN3 | 624..>667 | CDD:238020 | 19/42 (45%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 688..709 | 2/20 (10%) | |||
Insulin-binding. /evidence=ECO:0000250 | 735..743 | 4/7 (57%) | |||
FN3 | 869..946 | CDD:238020 | |||
Important for interaction with IRS1, SHC1 and STAT5B. /evidence=ECO:0000250 | 998..1001 | ||||
PTKc_InsR | 1018..1305 | CDD:133192 | |||
Pkinase_Tyr | 1025..1292 | CDD:285015 | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1361..1384 | ||||
PIK3R1 binding. /evidence=ECO:0000250 | 1363..1366 | ||||
Sdr | NP_001287331.1 | Recep_L_domain | 58..173 | CDD:279382 | 44/120 (37%) |
Furin-like | 209..332 | CDD:279142 | 36/145 (25%) | ||
Recep_L_domain | 347..461 | CDD:279382 | 45/116 (39%) | ||
FN3 | 491..578 | CDD:214495 | 39/106 (37%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 1 | 1.000 | 83 | 1.000 | Domainoid score | I8331 |
eggNOG | 1 | 0.900 | - | - | E2759_KOG4258 | |
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoDB | 1 | 1.010 | - | - | D120934at33208 | |
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
4 | 3.820 |