Protein Alignment ZNF579 and rst2

DIOPT Version :10

• Sequence 1: XP_016881898.1
• Gene: ZNF579 / 163033
• HGNCID: 26646
• Length: 640
• Species: Homo sapiens
• Sequence 2: NP_593288.1
• Gene: rst2 / 2543031
• PomBaseID: SPAC6F12.02
• Length: 567
• Species: Schizosaccharomyces pombe
• Alignment Length: 247
• Identity: 56/247 - (22%)
• Similarity: 84/247 - (34%)
• Gaps: 84/247 - (34%)

Human   374 PARPPAGEPRFWCPECGKGFRRRAHLRQHGVTHSGARPFQCVRCQREFKRLADLARHAQVHAGGP 438
            |..||....::.|..|.:.|.|..||::|..:|:..:||.|....                 |.|
pombe    60 PNAPPQKVKQYVCETCTRAFARLEHLKRHIRSHTNEKPFTCSEID-----------------GLP 107

Human   439 APHPCPRCPRRFSRAYSLLRH-QRCHRAELERAAALQALQAQAPTSPPPPPPPLKAEQEEEGLPL 502
            .     .|.|:|||...|||| |:.||                      .|.|.:..:....||.
pombe   108 T-----GCGRQFSRRDLLLRHQQKIHR----------------------NPQPRRRRRSTTALPN 145

Human   503 P-LANIKEEPPSPGTPPQSPPAPPVFLSASCFDSQD-------HSAFEME-------------EE 546
            | |:|:.....:..:.|        .:|....||.|       |:|.:.:             :.
pombe   146 PSLSNVSVSTTNLASKP--------VISLPQADSIDKFRYPKLHAALQAQLANNSGSFSASWLQA 202

Human   547 EAGRLGKKGGGQLARGMET-GGDAPASLSPVSHTGHHHLFGTARPWG--SPV 595
            :..||...|.|:     || ...|..:::|.|........|.  |:|  ||:
pombe   203 QQQRLVSAGNGR-----ETVNASASGAVNPTSSQWSDQRLGV--PYGPDSPL 247

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF579	XP_016881898.1	COG5048	45..>105	CDD:227381
		C2H2 Zn finger	46..66	CDD:275368
		zf-C2H2	72..94	CDD:395048
		C2H2 Zn finger	74..94	CDD:275368
		C2H2 Zn finger	102..119	CDD:275368
		C2H2 Zn finger	232..254	CDD:275368
		C2H2 Zn finger	272..292	CDD:275368
		zf-C2H2	298..320	CDD:395048
		C2H2 Zn finger	300..320	CDD:275368
		C2H2 Zn finger	386..406	CDD:275368	7/19 (37%)
		C2H2 Zn finger	414..434	CDD:275368	1/19 (5%)
		C2H2 Zn finger	443..463	CDD:275368	10/20 (50%)
rst2	NP_593288.1	COG5048	37..547	CDD:227381	56/247 (23%)
		C2H2 Zn finger	72..92	CDD:275368	7/19 (37%)
		C2H2 Zn finger	100..128	CDD:275368	13/49 (27%)