Protein Alignment ZNF497 and Zfy1

DIOPT Version :10

• Sequence 1: NP_940860.2
• Gene: ZNF497 / 162968
• HGNCID: 23714
• Length: 498
• Species: Homo sapiens
• Sequence 2: XP_038956652.1
• Gene: Zfy1 / 103694540
• RGDID: 9203794
• Length: 781
• Species: Rattus norvegicus
• Alignment Length: 548
• Identity: 148/548 - (27%)
• Similarity: 212/548 - (38%)
• Gaps: 90/548 - (16%)

Human    13 PEE---GQVLCNVKTATRGLSEGAVSGGWGAWENSTEVPRE-----AGDGQRQQ--ATLGAADEQ 67
            |||   |:.:..|::.|...:|..|..    ..:|..|||:     ..|.|:::  ..:...||.
  Rat   249 PEEDDVGETVDIVESKTDNGNEAEVID----QSSSIYVPRDNVYMPVSDSQKEEEDTKVIVGDED 309

Human    68 GGPGRELGPADGGRDGAGPRSEPADRALRPSPLPEEPGCRCGECGKAFSQGSYLLQHRRV----- 127
            .|        |...|.:....:..|..::.:.||.       ....|:...|..::.:.|
  Rat   310 AG--------DTAADTSEHEQQMDDSEIKAAFLPI-------AWAAAYDNNSDEIEEQNVTASAV 359

Human   128 -HTGE----------------KP--------------------YTCPECGKAFAWSSNLSQHQRI 155
             |..|                :|                    |.|..|||.|...|.|.:|.:.
  Rat   360 LHQNESGGLDRVHKQKAKKKKRPESKQYQTAIIVAPDGQTLIVYPCMFCGKKFKTKSFLKRHIKN 424

Human   156 HS---GEKPYACREC----GKAFRAHSQLIHHQETHSGLKPFRCPDCGKSFGRSTTLVQHRR-TH 212
            |.   .:|.|.|.:|    .|....|:.:..|:.|....|...|.||||....:.||..|:: ..
  Rat   425 HPEYLAKKKYHCTDCDYSTNKKISLHNHMESHKLTIKTEKTTECDDCGKHLSHAGTLCTHKKEKE 489

Human   213 TGEKPYECPEC----GKAFSWNSNFLEHRRVHTGARPHACRDCGKAFSQSSNLAEHLKIHAGARP 273
            ...|.|:|..|    .:..|.|.:.|   .||:...||.|.:|||.|...|.|.:|:::|.|.:|
  Rat   490 KVSKTYKCKFCDYETAEQTSLNHHLL---AVHSKKYPHVCVECGKGFRHPSELKKHIRVHTGEKP 551

Human   274 HACPDCGKAFVRVAGLRQHRRT-HSSEKPFPCAECGKAFRESSQLLQHQRTHTGERPFECAECGQ 337
            :.|..|.......:.|:.|.:| ||.:.|..|..|...|.::.:..||...|...|..:|:.|..
  Rat   552 YQCQYCEYKSADSSNLKTHIKTKHSKDIPLKCGICLMTFSDTKEAQQHALIHQENRTHQCSYCNH 616

Human   338 AFVMGSYLAEH-RRVHTGEKPHACAQCGKAFSQRSNLLSHRRTHSGAKPFACADCGKAFRGSSGL 401
            .....|.|..| ..|||.:.||.|..|.|.|.:.|.|..|..||...|...|..|.........|
  Rat   617 KSSNSSDLKRHIISVHTKDYPHKCDMCSKGFHRPSELKKHVATHKSKKMHQCRHCDFKSPDPFLL 681

Human   402 AHHRLS-HTGERPFACAECGKAFRGSSELRQHQRLHSGERPFVCAHCSKAFVRKSELLSH-RRTH 464
            :.|.|| ||...||.|..|.|.||...||::|.:.|||.:.:.|.:|..:....|....| ...|
  Rat   682 SRHILSVHTKNVPFKCKRCKKGFRQQCELQKHMKTHSGRKVYQCEYCEYSTTDASGFKRHVISIH 746

Human   465 TGERPYACGECGKPFSHRCNLNEHQKRH 492
            |.:.|:.|..|.|.|......|:|..||
  Rat   747 TKDYPHRCEYCKKGFRRPSEKNQHIMRH 774

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ZNF497	NP_940860.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	30..104		16/80 (20%)
		COG5048	107..492	CDD:227381	124/442 (28%)
		C2H2 Zn finger	108..128	CDD:275368	3/25 (12%)
		C2H2 Zn finger	136..156	CDD:275368	8/19 (42%)
		C2H2 Zn finger	164..184	CDD:275368	5/23 (22%)
		C2H2 Zn finger	192..212	CDD:275368	8/20 (40%)
		C2H2 Zn finger	220..240	CDD:275368	5/23 (22%)
		C2H2 Zn finger	248..268	CDD:275368	8/19 (42%)
		C2H2 Zn finger	276..296	CDD:275368	5/20 (25%)
		C2H2 Zn finger	304..324	CDD:275368	5/19 (26%)
		C2H2 Zn finger	332..352	CDD:275368	5/20 (25%)
		C2H2 Zn finger	360..380	CDD:275368	7/19 (37%)
		C2H2 Zn finger	388..408	CDD:275368	6/20 (30%)
		C2H2 Zn finger	416..436	CDD:275368	8/19 (42%)
		C2H2 Zn finger	444..464	CDD:275368	4/20 (20%)
		C2H2 Zn finger	472..492	CDD:275368	6/19 (32%)
Zfy1	XP_038956652.1	Zfx_Zfy_act	68..388	CDD:461400	28/157 (18%)
		zf-C2H2	403..425	CDD:395048	9/21 (43%)
		C2H2 Zn finger	405..425	CDD:275368	8/19 (42%)
		C2H2 Zn finger	436..456	CDD:275368	4/19 (21%)
		C2H2 Zn finger	468..484	CDD:275368	7/15 (47%)
		C2H2 Zn finger	497..518	CDD:275368	5/23 (22%)
		COG5048	508..>694	CDD:227381	61/188 (32%)
		C2H2 Zn finger	526..546	CDD:275368	8/19 (42%)
		zf-H2C2_2	538..562	CDD:463886	7/23 (30%)
		C2H2 Zn finger	554..573	CDD:275368	4/18 (22%)
		C2H2 Zn finger	583..603	CDD:275368	5/19 (26%)
		C2H2 Zn finger	611..632	CDD:275368	5/20 (25%)
		C2H2 Zn finger	640..689	CDD:275368	16/48 (33%)
		zf-C2H2	695..717	CDD:395048	9/21 (43%)
		C2H2 Zn finger	697..717	CDD:275368	8/19 (42%)
		zf-H2C2_2	709..733	CDD:463886	8/23 (35%)
		C2H2 Zn finger	725..746	CDD:275368	4/20 (20%)
		C2H2 Zn finger	754..774	CDD:275368	6/19 (32%)