Protein Alignment DBT and KGD2

DIOPT Version :9

• Sequence 1: NP_001909.4
• Gene: DBT / 1629
• HGNCID: 2698
• Length: 482
• Species: Homo sapiens
• Sequence 2: NP_010432.3
• Gene: KGD2 / 851726
• SGDID: S000002555
• Length: 463
• Species: Saccharomyces cerevisiae
• Alignment Length: 431
• Identity: 116/431 - (26%)
• Similarity: 194/431 - (45%)
• Gaps: 55/431 - (12%)

Human    66 QFKLSDI-----GEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNL 125
            :||.:.|     .|.:.|.::||:....||.:.:.:.:..:::||..:.:.|...|.:.||.:..
Yeast    70 RFKSTSIEVPPMAESLTEGSLKEYTKNVGDFIKEDELLATIETDKIDIEVNSPVSGTVTKLNFKP 134

Human   126 DDIAYVGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLAMENNIKLSE 190
            :|...||:.|..:|      ..|...|....|..|.|.|        |.|:....|.||:   ||
Yeast   135 EDTVTVGEELAQVE------PGEAPAEGSGESKPEPTEQ--------AEPSQGVAARENS---SE 182

Human   191 VVGSGKDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPV----FTGKD 251
            ...|.|:....||               .:||.|:..|....:.........:|||    ||...
Yeast   183 ETASKKEAAPKKE---------------AAPKKEVTEPKKADQPKKTVSKAQEPPVASNSFTPFP 232

Human   252 KTEP-IK------GFQKAMVKTMSAALKIPHFGYCDEIDLTELVKLREELK-PIAFARGIKLSFM 308
            :||. :|      ...:.:.::.:.|..:..|   :|:|::.|:::|:..| .|....|.|..||
Yeast   233 RTETRVKMNRMRLRIAERLKESQNTAASLTTF---NEVDMSALMEMRKLYKDEIIKKTGTKFGFM 294

Human   309 PFFLKAASLGLLQFPILNASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATE 373
            ..|.||.:|.....|.:|.:::.:  .|.|:...:|.:|:.|.:||:.|.|:|.:..|:.||..|
Yeast   295 GLFSKACTLAAKDIPAVNGAIEGD--QIVYRDYTDISVAVATPKGLVTPVVRNAESLSVLDIENE 357

Human   374 LNRLQKLGSVSQLSTTDLTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEV 438
            :.||.......:|:..|:||||||:||.|..|..:..|:|..|:.|:..|..:|..| ....|::
Yeast   358 IVRLSHKARDGKLTLEDMTGGTFTISNGGVFGSLYGTPIINSPQTAVLGLHGVKERP-VTVNGQI 421

Human   439 YKAQIMNVSWSADHRVIDGATMSRFSNLWKSYLENPAFMLL 479
            ....:|.::.:.|||::||.....|....|..:|:|..|||
Yeast   422 VSRPMMYLALTYDHRLLDGREAVTFLKTVKELIEDPRKMLL 462

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DBT	NP_001909.4	PLN02528	67..482	CDD:215289	116/430 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..168		6/20 (30%)
KGD2	NP_010432.3	sucB	74..463	CDD:273565	114/427 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG0508
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.810