Protein Alignment DBT and Dbt

DIOPT Version :10

• Sequence 1: NP_001909.4
• Gene: DBT / 1629
• HGNCID: 2698
• Length: 482
• Species: Homo sapiens
• Sequence 2: NP_445764.1
• Gene: Dbt / 29611
• RGDID: 68403
• Length: 482
• Species: Rattus norvegicus
• Alignment Length: 482
• Identity: 422/482 - (87%)
• Similarity: 452/482 - (93%)
• Gaps: 0/482 - (0%)

Human     1 MAAVRMLRTWSRNAGKLICVRYFQTCGNVHVLKPNYVCFFGYPSFKYSHPHHFLKTTAALRGQVV 65
            |||.|:|.||||||.:|.|||||||..|||:|||.:||..|||..|.|.|.|.|:|.|.|:||||
  Rat     1 MAAARVLGTWSRNAVRLTCVRYFQTYNNVHILKPQHVCSVGYPLLKSSQPRHSLRTAAVLQGQVV 65

Human    66 QFKLSDIGEGIREVTVKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKKLYYNLDDIAY 130
            |||||||||||||||:||||||||||||||||||||||||||||||||||||||:||||||||||
  Rat    66 QFKLSDIGEGIREVTIKEWYVKEGDTVSQFDSICEVQSDKASVTITSRYDGVIKRLYYNLDDIAY 130

Human   131 VGKPLVDIETEALKDSEEDVVETPAVSHDEHTHQEIKGRKTLATPAVRRLAMENNIKLSEVVGSG 195
            |||||:||||||||||||||||||||:|||||||||||:||||||||||||||||||||||||||
  Rat   131 VGKPLIDIETEALKDSEEDVVETPAVAHDEHTHQEIKGQKTLATPAVRRLAMENNIKLSEVVGSG 195

Human   196 KDGRILKEDILNYLEKQTGAILPPSPKVEIMPPPPKPKDMTVPILVSKPPVFTGKDKTEPIKGFQ 260
            ||||||||||||:||||||||||||||.||.||||:|:|...|..|||||||.|||:|||:.|||
  Rat   196 KDGRILKEDILNFLEKQTGAILPPSPKSEITPPPPQPRDRPFPTPVSKPPVFLGKDRTEPVTGFQ 260

Human   261 KAMVKTMSAALKIPHFGYCDEIDLTELVKLREELKPIAFARGIKLSFMPFFLKAASLGLLQFPIL 325
            |||||||||||||||||||||:||||||||||||||:|.||||||||||||||||||||||||||
  Rat   261 KAMVKTMSAALKIPHFGYCDEVDLTELVKLREELKPVALARGIKLSFMPFFLKAASLGLLQFPIL 325

Human   326 NASVDENCQNITYKASHNIGIAMDTEQGLIVPNVKNVQICSIFDIATELNRLQKLGSVSQLSTTD 390
            |||||||||:||||||||||||||||:|||||||||||:.|:|:||.||||||||||:.||||||
  Rat   326 NASVDENCQSITYKASHNIGIAMDTERGLIVPNVKNVQVRSVFEIAMELNRLQKLGSLGQLSTTD 390

Human   391 LTGGTFTLSNIGSIGGTFAKPVIMPPEVAIGALGSIKAIPRFNQKGEVYKAQIMNVSWSADHRVI 455
            |||||||||||||||||:|||||:||||||||||:|||:|||:|||:||||||||||||||||||
  Rat   391 LTGGTFTLSNIGSIGGTYAKPVILPPEVAIGALGAIKALPRFDQKGDVYKAQIMNVSWSADHRVI 455

Human   456 DGATMSRFSNLWKSYLENPAFMLLDLK 482
            |||||||||||||||||||||||||||
  Rat   456 DGATMSRFSNLWKSYLENPAFMLLDLK 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DBT	NP_001909.4	PLN02528	67..482	CDD:215289	377/414 (91%)
		Critical for association with PPM1K. /evidence=ECO:0000269|PubMed:22291014	145..160		13/14 (93%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	147..168		19/20 (95%)
Dbt	NP_445764.1	PLN02528	67..482	CDD:215289	377/414 (91%)