Protein Alignment DAZL and lark

DIOPT Version :10

• Sequence 1: NP_001177740.1
• Gene: DAZL / 1618
• HGNCID: 2685
• Length: 315
• Species: Homo sapiens
• Sequence 2: NP_523957.1
• Gene: lark / 38811
• FlyBaseID: FBgn0011640
• Length: 352
• Species: Drosophila melanogaster
• Alignment Length: 297
• Identity: 64/297 - (21%)
• Similarity: 100/297 - (33%)
• Gaps: 99/297 - (33%)

Human    33 ISREASTQSSSAATS-QGYILPEGKI---------MPNT----VFVGGIDVRMDETEIRSFFARY 83
            :..|...|...|..: .||.|.|..|         .|||    :|||.:..:....|:|..|.:|
  Fly    45 VHMETEQQGRDAIQNLNGYTLNEFAIKVEAAKSRRAPNTPTTKIFVGNLTDKTRAPEVRELFQKY 109

Human    84 GSVKEVKIITDRTGVSKGYGFVSFFNDVDVQKIVESQIN---FHGKKLKLGPAIRKQNLCAYHVQ 145
            |:|.|..|:       :.||||......|||..:: ::|   ..|:.||:       .:....|:
  Fly   110 GTVVECDIV-------RNYGFVHLDCVGDVQDAIK-ELNGRVVDGQPLKV-------QVSTSRVR 159

Human   146 PRPLVFNHPPPPQFQNV-----WTNPNTETY------MQPTTTM------------NPITQYVQA 187
            |:|   ....|.|....     |:......|      .:|.:.:            :|
  Fly   160 PKP---GMGDPEQCYRCGRSGHWSKECPRLYGSAGGGREPPSPLSAGGYRDRMYGRDP------- 214

Human   188 YPTYPNSPV----QVITGYQLPVYNY----------------------QMPPQWPVGEQRSYVVP 226
            ||..|..|.    :::.|::  .|:|                      ..||. |:..:....:|
  Fly   215 YPPPPPPPPFLRDRIMDGFR--DYDYYDRRFEDSRDLYERRYQTSRMRDFPPP-PISRREPMPLP 276

Human   227 PAYSAVNYHCNEVDPGAEVVPNECSVHEATPP-SGNG 262
            |..|.....|: |..|.:.:   .|.....|| |.||
  Fly   277 PTLSGSLRSCS-VSRGYDTM---FSRRSPPPPRSSNG 309

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
DAZL	NP_001177740.1	RRM_DAZL	55..136	CDD:410073	26/96 (27%)
		PABP-1234	<60..228	CDD:130689	44/223 (20%)
lark	NP_523957.1	RRM1_2_CoAA_like	8..73	CDD:409779	8/27 (30%)
		RRM1_2_CoAA_like	87..152	CDD:409779	22/79 (28%)
		hnRNP-R-Q	<88..>258	CDD:273732	38/196 (19%)